Sarah Walmsley

2024

How oxygenation shapes immune responses: emerging roles for physioxia and pathological hypoxia

Mirchandani, A. S., Sanchez Garcia, M. A. & Walmsley, S. R., 30 Sept 2024, In: Nature Reviews Immunology.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Primary cilia as a targetable node between biliary injury, senescence and regeneration in liver transplantation

Esser, H., Kilpatrick, A. M., Man, T. Y., Aird, R., Rodrigo-Torres, D., Buch, M. L., Boulter, L., Walmsley, S., Oniscu, G. C., Schneeberger, S., Ferreira-Gonzalez, S. & Forbes, S. J., 13 Jun 2024, (E-pub ahead of print) In: Journal of Hepatology.

Research output: Contribution to journal › Article › peer-review

Open Access

Accelarated immune ageing is associated with COVID-19 disease severity

ISARIC4C Investigators, Adeloye, D., Baillie, JK., Bularga, A., Daines, L., Lone, NI., Mills, NL., Newby, DE., Pius, R., Shankar-Hari, M., Sheikh, A., Sudlow, CL., Walmsley, S. & Zheng, B., 11 Jan 2024, In: Immunity and Ageing. 21, 1, 18 p., 6.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2023

Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function

Watts, E., Willson, J. A., Arienti, S., Sadiku, P., Coelho, P., Sanchez Garcia, M. A., Zhang, A., Murphy, F., Dickinson, R., Mirchandani, A. S., Morrison, T., Lewis, A., Vermaelen, W., Ghesquiere, B., Carmeliet, P., Mazzone, M., Maxwell, P. H., Pugh, C. W., Dockrell, D. H., Whyte, M., & 1 othersWalmsley, S. R., 11 Dec 2023, (E-pub ahead of print) In: Wellcome Open Research .

Research output: Contribution to journal › Article › peer-review

Open Access

File

Long COVID research: an update from the PHOSP-COVID Scientific Summit

PHOSP-COVID Collaborative Group, 1 Nov 2023, In: The Lancet Respiratory Medicine. 11, 11, p. e93-e94

Research output: Contribution to journal › Letter › peer-review

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

The C-MORE/PHOSP-COVID Collaborative Group, Nov 2023, In: The Lancet Respiratory Medicine. 11, 11, p. 1003-1019 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

S96 Neutrophil metabolism is reprogrammed in patients with acute respiratory distress syndrome

Cooper, G., Sadiku, P., Griffith, D. M. & Walmsley, S. R., 7 Jul 2023, In: Thorax. 77, p. A60-A61 2 p., s96.

Research output: Contribution to journal › Meeting abstract › peer-review

NRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD

Ryan, E., Sadiku, P., Coelho, P., Watts, E. R., Zhang, A., Howden, A. J. M., Sanchez Garcia, M. A., Bewley, M. A., Cole, J., McHugh, B., Vermaelen, W., Ghesquiere, B., Carmeliet, P., Rodriguez Blanco, G., von Kriegsheim, A., Sanchez, Y., Rumsey, W., Callahan, J. F., Cooper, G., Parkinson, N., & 8 othersBaillie, J. K., Cantrell, D., McCafferty, J., Choudhury, G., Singh, D., Dockrell, D. H., Whyte, M. K. B. & Walmsley, S. R., 1 Feb 2023, (E-pub ahead of print) In: American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2022

The emerging role for metabolism in fueling neutrophilic inflammation

Morrison, T., Watts, E. R., Sadiku, P. & Walmsley, S. R., 3 Nov 2022, In: Immunological reviews.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Sanchez Garcia, M. A., Lawson, H., Coelho, P., Murphy, F., Griffith, D., Zhang, A., Morrison, T., Ly, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R., Reyes, L., Cooper, G., Clark, S., Lewis, D., Kelly, V., & 22 othersSpanos, C., Musgrave, K. M., Delaney, L., Harper, I., Scott, J., Parkinson, N., Rostron, A. J., Baillie, J. K., Clohisey, S., Pridans, C., Campana, L., Starkey Lewis, P., Simpson, A. J., Dockrell, D. H., Schwarze, J., Hirani, N., Ratcliffe, P. J., Pugh, C. W., Kranc, K., Forbes, S. J., Whyte, M. K. B. & Walmsley, S. R., 27 May 2022, In: Nature Immunology.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence

Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Lawson, H., Coelho, P., Murphy, F., Griffith, D., Zhang, A., Sanchez-Garcia, M. A., Reyes, L., Morrison, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R. S., Clark, S., Ly, T., Lewis, D., Kelly, V., Spanos, C., & 21 othersMusgrave, K. M., Delaney, L., Harper, I., Scott, J., Parkinson, N. J., Rostron, A. J., Baillie, K. J., Clohisey, S., Pridans, C., Campana, L., Starkey-Lewis, P., Simpson, A. J., Dockrell, D., Schwarze, J., Hirani, N., Ratcliffe, P. J., Pugh, C. W., Kranc, K., Forbes, S. J., Whyte, M. K. & Walmsley, S. R., 12 Mar 2022, bioRxiv, p. 1-53, 53 p.

Research output: Working paper › Preprint

2021

The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair

Mccowan, J., Fercoq, F., Kirkwood, P. M., T’jonck, W., Hegarty, L. M., Mawer, C. M., Cunningham, R., Mirchandani, A. S., Hoy, A., Humphries, D. C., Jones, G., Hansen, C. G., Hirani, N., Jenkins, S. J., Henri, S., Malissen, B., Walmsley, S. R., Dockrell, D. H., Saunders, P. T. K., Carlin, L. M., & 1 othersBain, C. C., 19 Nov 2021, In: Science Immunology. 6, 65

Research output: Contribution to journal › Article › peer-review

Open Access

File

Neutrophil HIF-1α stabilisation is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle

Willson, J. A., Arienti, S., Sadiku, P., Reyes, L., Coelho, P., Morrison, T., Rinaldi, G., Dockrell, D. H., Whyte, M. K. B. & Walmsley, S. R., 19 Aug 2021, In: Blood.

Research output: Contribution to journal › Article › peer-review

Open Access

File

A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS

Reyes, L., Sanchez Garcia, M. A., Morrison, T., Howden, A. J. M., Watts, E. R., Arienti, S., Sadiku, P., Coelho, P., Mirchandani, A. S., Zhang, A., Hope, D., Clark, S. K., Singleton, J., Johnston, S., Grecian, R., Poon, A. S., McNamara, S., Harper, I., Fourman, M. H., Brenes, A. J., & 14 othersPathak, S., Lloyd, A., Rodriguez Blanco, G., von Kriegsheim, A., Ghesquiere, B., Vermaelen, W., Cologna, C. T., Dhaliwal, K., Hirani, N., Dockrell, D. H., Whyte, M. K. B., Griffith, D. M., Cantrell, D. & Walmsley, S. R., 25 Jun 2021, (E-pub ahead of print) Wellcome Open Research, (wellcome Open Research).

Research output: Working paper

Open Access

File

Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation

Virga, F., Cappellesso, F., Stijlemans, B., Henze, A-T., Trotta, R., Van Audenaerde, J., Mirchandani, A. S., Sanchez Garcia, M. A., Vandewalle, J., Orso, F., Riera-Domingo, C., Griffa, A., Ivan, C., Smits, E., Laoui, D., Martelli, F., Langouche, L., Van den Berghe, G., Feron, O., Ghesquiere, B., & 8 othersPrenen, H., Libert, C., Walmsley, S. R., Corbet, C., Van Ginderachter, J. A., Ivan, M., Taverna, D. & Mazzone, M., 7 May 2021, In: Science Advances.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism

Watts, E. R., Howden, A. J. M., Morrison, T., Sadiku, P., Hukelmann, J. L., Von Kriegsheim, A., Ghesquière, B., Murphy, F., Mirchandani, A. S., Humphries, D. C., Grecian, R., Ryan, E. M., Coelho, P., Rodriguez-blanco, G., Plant, T. M., Dickinson, R. S., Finch, A. J., Vermaelen, W., Cantrell, D. A., Whyte, M. K. B., & 1 othersWalmsley, S. R., 6 Apr 2021, (E-pub ahead of print) In: Journal of Clinical Investigation.

Research output: Contribution to journal › Article › peer-review

Open Access

File

A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS

Reyes, L., Sanchez Garcia, M. A., Morrison, T., Howden, A. J. M., Watts, E. R., Arienti, S., Sadiku, P., Coelho, P., Mirchandani, A. S., Zhang, A., Hope, D., Clark, S. K., Singleton, J., Johnston, S., Grecian, R., Poon, A. S., McNamara, S., Harper, I., Fourman, M. H., Brenes, A. J., & 14 othersPathak, S., Lloyd, A., Rodriguez Blanco, G., von Kriegsheim, A., Ghesquiere, B., Vermaelen, W., Cologna, C. T., Dhaliwal, K., Hirani, N., Dockrell, D. H., Whyte, M. K. B., Griffith, D. M., Cantrell, D. & Walmsley, S. R., 22 Feb 2021, In: Wellcome Open Research .

Research output: Contribution to journal › Article › peer-review

Open Access

File

S47 The NSCLC pleural metastatic environment influences the role neutrophils play in the immune checkpoint

Grecian, R., Gwyer Findlay, E., Dhaliwal, K., Byron, A., Frame, M., Whyte, M. & Walmsley, S., 21 Feb 2021, p. A30.1-A30.

Research output: Contribution to conference › Abstract

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

Sadiku, P., Willson, J. A., Ryan, E. M., Sammut, D., Coelho, P., Watts, E. R., Grecian, R., Young, J. M., Bewley, M., Arienti, S., Mirchandani, A. S., Sanchez Garcia, M. A., Morrison, T., Zhang, A., Reyes, L., Griessler, T., Jheeta, P., Paterson, G. G., Graham, C. J., Thompson, J. P., & 16 othersBaillie, K., Thompson, A. A. R., Morgan, J-M., Acosta-Sanchez, A., Dardé, V. M., Duran, J., Guinovart, J. J., Rodriguez-Blanco, G., Von Kriegsheim, A., Meehan, R. R., Mazzone, M., Dockrell, D. H., Ghesquiere, B., Carmeliet, P., Whyte, M. K. B. & Walmsley, S. R., 2 Feb 2021, In: Cell Metabolism. 33, 2, p. 411-423.e4

Research output: Contribution to journal › Article › peer-review

Open Access

File

2020

Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

Bain, C. C., Gibson, D. A., Steers, N. J., Boufea, K., Louwe, P. A., Doherty, C., González-huici, V., Gentek, R., Magalhaes-pinto, M., Shaw, T., Bajénoff, M., Bénézech, C., Walmsley, S. R., Dockrell, D. H., Saunders, P. T. K., Batada, N. N. & Jenkins, S. J., 26 Jun 2020, In: Science Immunology. 5, 48, eabc4466.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Semaphorin 3F signaling actively retains neutrophils at sites of inflammation

Plant, T., Eamsamarng, S., Sanchez-Garcia, M. A., Reyes, L., Renshaw, S. A., Coelho, P., Mirchandani, A. S., Morgan, J-M., Ellett, F. E., Morrison, T., Humphries, D., Watts, E. R., Murphy, F., Raffo-Iraolagoitia, X. L., Zhang, A., Cash, J. L., Loynes, C., Elks, P. M., Van Eeden, F., Carlin, L. M., & 3 othersFurley, A. J. W., Whyte, M. K. B. & Walmsley, S. R., 1 Jun 2020, In: Journal of Clinical Investigation. 130, 6, p. 3221-3237

Research output: Contribution to journal › Article › peer-review

Open Access

File

The NSCLC pleural metastatic environment influences the role neutrophils play in the immune checkpoint

Grecian, R., Findlay, E. G., Dhaliwal, K., Byron, A., Frame, M., Whyte, M. & Walmsley, S., 1 Jan 2020.

Research output: Contribution to conference › Abstract

2019

Hypoxia modulates platelet purinergic signalling pathways

Paterson, G. G., Young, J. M., Willson, J. A., Graham, C. J., Dru, R. C., Lee, E. W., Torpey, G. S., Walmsley, S., Chan, M. V., Warner, T. D., Baillie, K. & Roger Thompson, A. A., 13 Dec 2019, (E-pub ahead of print) In: Thrombosis and Haemostasis.

Research output: Contribution to journal › Article › peer-review

Open Access

File

IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo

Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J., & 2 othersWhyte, M. K. B. & Walmsley, S. R., 15 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235–246 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Hypoxia and the regulation of myeloid cell metabolic imprinting: consequences for the inflammatory response

Sadiku, P. & Walmsley, S. R., 14 Mar 2019, (E-pub ahead of print) In: EMBO Reports. p. e47388

Research output: Contribution to journal › Article › peer-review

Open Access

File

2018

Hypoxia and reprogramming of host pathogen interactions

Ryan, E. M., Whyte, M. K. & Walmsley, S. R., 27 Nov 2018, (E-pub ahead of print) In: Current opinion in physiology. 7, p. 15-20

Research output: Contribution to journal › Article › peer-review

Open Access

File

Inflammation and Hypoxia: HIF and PHD Isoform Selectivity

Watts, E. R. & Walmsley, S. R., 1 Nov 2018, In: Trends in Molecular Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists

COPDMAP, Bewley, M. A., Budd, R. C., Ryan, E., Cole, J., Collini, P., Marshall, J., Kolsum, U., Beech, G., Emes, R. D., Tcherniaeva, I., Berbers, G. A. M., Walmsley, S. R., Donaldson, G., Wedzicha, J. A., Kilty, I., Rumsey, W., Sanchez, Y., Brightling, C. E., Donnelly, L. E., & 4 othersBarnes, P. J., Singh, D., Whyte, M. K. B. & Dockrell, D. H., 15 Sept 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 6, p. 739-750 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

The role of neutrophils in cancer

Grecian, R., Whyte, M. & Walmsley, S., 22 Aug 2018, In: British Medical Bulletin.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Getting DAMP(s) Wets the Whistle for Neutrophil Recruitment

Watts, E. R. & Walmsley, S. R., 15 May 2018, (E-pub ahead of print) In: Immunity. 48, 5, p. 846-848 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2017

Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo

Dickinson, R. S., Murphy, F., Doherty, C., Williams, S., Mirchandani, A., Willson, J. A., Scotti, J. S., Preston, G., Schofield, C. J., Whyte, M. K. B. & Walmsley, S. R., 26 Oct 2017, In: Wellcome Open Research . 2, p. 104

Research output: Contribution to journal › Article › peer-review

Open Access

File

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

Sadiku, P., Willson, J. A., Dickinson, R., Murphy, F., Harris, A., Lewis, A., Sammut, D., Mirchandani, A. S., Ryan, E., Watts, E. R., Thompson, A. A. R., Marriott, H. M., Dockrell, D. H., Taylor, C. T., Schneider, M., Maxwell, P. H., Chilvers, E. R., Mazzone, M., Moral, V., Pugh, C. W., & 6 othersRatcliffe, P. J., Schofield, C. J., Ghesquiere, B., Carmeliet, P., Whyte, M. K. B. & Walmsley, S. R., 1 Sept 2017, In: Journal of Clinical Investigation. 127, 9, p. 3407-3420 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism

Thompson, A. A. R., Dickinson, R. S., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J., Williams, L., Lewis, A., Mirchandani, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N. M., Forbes, S., Stimson, R. H., Hameed, A. G., Arnold, N., Preston, J. A., & 15 othersLawrie, A., Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R. R., Whyte, M. K. B. & Walmsley, S. R., 24 Feb 2017, In: Science Immunology. 2, 8, eaal2861.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Hypoxia and host pathogen responses

Walmsley, S. R. & Rupp, J., 20 Jan 2017, (E-pub ahead of print) In: Microbes and Infection. 19, 3, p. 143

Research output: Contribution to journal › Editorial › peer-review

Open Access

File

2016

Mutations in Succinate Dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1alpha expression

Jones, R., McDonald, K. E., Willson, J. A., Ghesquiere, B., Sammut, D., Daniel, E., Harris, A. J., Lewis, A., Thompson, A. A. R., Dickinson, R. S., Plant, T., Murphy, F., Sadiku, P., Keevil, B. G., Carmeliet, P., Whyte, M. K. B., Newell-Price, J. & Walmsley, S. R., 26 May 2016, In: Blood. 127, 21, p. 2641-2644 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2015

Exploring the HIFs, Buts and Maybes of Hypoxia Signalling in Disease: Lessons From Zebrafish Models

Elks, P. M., Renshaw, S. A., Meijer, A. H., Walmsley, S. & Van Eeden, F. J., 1 Nov 2015, In: Disease Models and Mechanisms. 8, 11, p. 1349-1360

Research output: Contribution to journal › Article › peer-review

Open Access

File

MET is required for the recruitment of anti-tumoural neutrophils

Finisguerra, V., Di Conza, G., Di Matteo, M., Serneels, J., Costa, S., Thompson, A. A. R., Wauters, E., Walmsley, S., Prenen, H., Granot, Z., Casazza, A. & Mazzone, M., 18 Jun 2015, In: Nature. 522, 7556, p. 349-353 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2014

A local circadian clock calls time on lung inflammation

Thompson, A. A. R., Walmsley, S. R. & Whyte, M. K. B., Aug 2014, In: Nature Medicine. 20, 8, p. 809-811 3 p.

Research output: Contribution to journal › Editorial

Neutrophil energetics and oxygen sensing

Walmsley, S. R. & Whyte, M. K. B., 1 May 2014, In: Blood. 123, 18, p. 2753-2754 4 p.

Research output: Contribution to journal › Editorial

HIF-mediated innate immune responses: cell signaling and therapeutic implications

AJ, H., Thompson, A. A. R., Whyte, M. & Walmsley, S., May 2014, In: Hypoxic Signaling. 2, p. 47-58

Research output: Contribution to journal › Literature review › peer-review

Open Access

File

A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

Robertson, A. L., Holmes, G. R., Bojarczuk, A. N., Burgon, J., Loynes, C. A., Chimen, M., Sawtell, A. K., Hamza, B., Willson, J., Walmsley, S. R., Anderson, S. R., Coles, M. C., Farrow, S. N., Solari, R., Jones, S., Prince, L. R., Irimia, D., Rainger, G. E., Kadirkamanathan, V., Whyte, M. K. B., & 1 othersRenshaw, S. A., 26 Feb 2014, In: Science Translational Medicine. 6, 225, 10 p., 225ra29.

Research output: Contribution to journal › Article › peer-review

Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish

Thompson, A. A. R., Elks, P. M., Marriott, H. M., Eamsamarng, S., Higgins, K. R., Lewis, A., Williams, L., Parmar, S., Shaw, G., McGrath, E. E., Formenti, F., Van Eeden, F. J., Kinnula, V. L., Pugh, C. W., Sabroe, I., Dockrell, D. H., Chilvers, E. R., Robbins, P. A., Percy, M. J., Simon, M. C., & 4 othersJohnson, R. S., Renshaw, S. A., Whyte, M. K. B. & Walmsley, S. R., 16 Jan 2014, In: Blood. 123, 3, p. 366-376 11 p.

Research output: Contribution to journal › Article › peer-review

2013

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

Elks, P. M., Brizee, S., van der Vaart, M., Walmsley, S. R., van Eeden, F. J., Renshaw, S. A. & Meijer, A. H., 19 Dec 2013, In: PLoS Pathogens. 9, 12, 16 p., 1003789.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Cezanne Regulates Inflammatory Responses to Hypoxia in Endothelial Cells by Targeting TRAF6 for Deubiquitination

Luong, L. A., Fragiadaki, M., Smith, J., Boyle, J., Lutz, J., Dean, J. L. E., Harten, S., Ashcroft, M., Walmsley, S. R., Haskard, D. O., Maxwell, P. H., Walczak, H., Pusey, C. & Evans, P. C., 7 Jun 2013, In: Circulation Research. 112, 12, p. 1583-1591 20 p.

Research output: Contribution to journal › Article › peer-review

Succinate is an inflammatory signal that induces IL-1 beta through HIF-1 alpha

Tannahill, G. M., Curtis, A. M., Adamik, J., Palsson-McDermott, E. M., McGettrick, A. F., Goel, G., Frezza, C., Bernard, N. J., Kelly, B., Foley, N. H., Zheng, L., Gardet, A., Tong, Z., Jany, S. S., Corr, S. C., Haneklaus, M., Caffrey, B. E., Pierce, K., Walmsley, S., Beasley, F. C., & 12 othersCummins, E., Nizet, V., Whyte, M., Taylor, C. T., Lin, H., Masters, S. L., Gottlieb, E., Kelly, V. P., Clish, C., Auron, P. E., Xavier, R. J. & O'Neill, L. A. J., 11 Apr 2013, In: Nature. 496, 7444, p. 238-242 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Hypoxia, the HIF pathway and neutrophilic inflammatory responses

Thompson, A. A. R., Binham, J., Plant, T., Whyte, M. K. B. & Walmsley, S. R., Apr 2013, In: Biological Chemistry. 394, 4, p. 471-477 7 p.

Research output: Contribution to journal › Literature review › peer-review

Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL-1 and clearance of chemokines

Basran, A., Jabeen, M., Bingle, L., Stokes, C. A., Dockrell, D., Whyte, M. K. B., Walmsley, S. R., Higgins, K. R., Vogel, S. N., Wilson, H. L., Prince, L. R., Prestwich, E. C., Sabroe, R. A., Parker, L. C. & Sabroe, I., Jan 2013, In: Journal of Leukocyte Biology. 93, 1, p. 7-19 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2012

A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia

Marriott, H. M., Daigneault, M., Thompson, A. A. R., Walmsley, S. R., Gill, S. K., Witcher, D. R., Wroblewski, V. J., Hellewell, P. G., Whyte, M. K. B. & Dockrell, D., Nov 2012, In: Thorax. 67, 11, p. 985-992 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival

Juss, J. K., Hayhoe, R. P., Owen, C. E., Bruce, I., Walmsley, S. R., Cowburn, A. S., Kulkarni, S., Boyle, K. B., Stephens, L., Hawkins, P. T., Chilvers, E. R. & Condliffe, A. M., 24 Sept 2012, In: PLoS ONE. 7, 9, 15 p., e45933.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

McGrath, E. E., Lawrie, A., Marriott, H. M., Mercer, P., Cross, S. S., Arnold, N., Singleton, V., Thompson, A. A. R., Walmsley, S. R., Renshaw, S. A., Sabroe, I., Chambers, R. C., Dockrell, D. & Whyte, M. K. B., Sept 2012, In: Thorax. 67, 9, p. 796-803 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Sarah Walmsley

Research output

Search results