Research output per year
Research output per year
Personal profile
My research in a nutshell
Understanding and controlling the mechanisms of redox enzymes.
Current Research Interests
Mammalian NO synthases, large multidomain enzymes involved in the regulation of blood flow/pressure, immune response and nerve signalling.
Heme-dependent monooxygenases, powerful catalysts able to insert oxygen atoms specifically into otherwise unreactive molecules.
Multiheme electron transfer proteins, used to build protein-based electron transfer wires for use in enzyme electrochemistry and in the construction of novel electroactive enzymes.
Administrative Roles
Industrial Placement Coordinator
Quality Assurance Director
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Research output
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NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA
Alvarez, L. A., Kovačič, L., Rodríguez, J., Gosemann, J-H., Kubica, M., Pircalabioru, G. G., Friedmacher, F., Cean, A., Ghişe, A., Sărăndan, M. B., Puri, P., Daff, S., Plettner, E., von Kriegsheim, A., Bourke, B. & Knaus, U. G., 13 Sept 2016, In: Proceedings of the National Academy of Sciences (PNAS). 113, 37, p. 10406-10411 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Cj1411c Encodes for a Cytochrome P450 Involved in Campylobacter jejuni 81-176 Pathogenicity
Alvarez, L., Bourke, B., Pircalabioru, G., Georgiev, A., Knaus, U., Daff, S. & Corcionivoschi, N., 26 Sept 2013, In: PLoS ONE. 8, 9, e75534.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Oxygen Activation in Neuronal NO Synthase: Resolving the Consecutive Monooxygenation Steps
Papale, D., Bruckmann, C., Gazur, B., Miles, C. S., Mowat, C. G. & Daff, S., 15 Apr 2012, In: Biochemical Journal. 443, 2, p. 505-514 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
An in situ electrochemical cell for Q- and W-band EPR spectroscopy
Murray, P. R., Collison, D., Daff, S., Austin, N., Edge, R., Flynn, B. W., Jack, L., Leroux, F., McInnes, E. J. L., Murray, A., Sells, D., Stevenson, T., Wolowska, J. & Yellowlees, L. J., Dec 2011, In: Journal of Magnetic Resonance. 213, 1, p. 206-209 4 p.Research output: Contribution to journal › Article › peer-review
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Cytochrome P450 BM3, NO binding and real-time NO detection
Ost, T. W. B., Liu, S. & Daff, S., 1 Aug 2011, In: Nitric Oxide. 25, 2, p. 89-94 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Projects
- 5 Finished
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Developing a Strategy for the Construction of Bioelectronic Nanodevices
1/01/10 → 31/07/13
Project: Research
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