Research output per year
Research output per year
Personal profile
Current Research Interests
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Neuroimaging studies of schizophrenia and related disorders, especially to identify genetic effects and for early detection
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Developing novel interventions for schizophrenia and those at high risk
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Building integrated biopsychosocial models of psychiatric disorders
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Dispelling myths and promoting truths about psychiatric disorders
My research in a nutshell
My overarching goal is to develop research tools to provide objective diagnoses and improve the management of major psychiatric disorder.
I am particularly interested in clinical applications of brain imaging in schizophrenia and other psychoses, and in the development of novel treatments that might enhance outcomes in established schizophrenia and possibly even prevent psychosis in high risk populations.
My own research has primarily involved using structural and functional brain imaging to distinguish patients with schizophrenia from their relatives, and from other patients with major psychiatric disorders such as bipolar disorder and autism.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis
Wang, B., Irizar, H., Thygesen, J. H., Zartaloudi, E., Austin-Zimmerman, I., Bhat, A., Harju-Seppänen, J., Pain, O., Bass, N., Gkofa, V., Alizadeh, B. Z., van Amelsvoort, T., Arranz, M. J., Bender, S., Cahn, W., Stella Calafato, M., Crespo-Facorro, B., Di Forti, M., Genetic Risk and Outcome of Psychosis (GROUP) Study, Giegling, I., & 28 others, 14 Aug 2023, (E-pub ahead of print) In: Schizophrenia Bulletin.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Inflammatory subgroups of schizophrenia and their association with brain structure: A semi-supervised machine learning examination of heterogeneity
Alexandros Lalousis, P., Schmaal, L., Wood, S. J., L E P Reniers, R., Cropley, V. L., Watson, A., Pantelis, C., Suckling, J., Barnes, N. M., Pariante, C., Jones, P. B., Joyce, E., Barnes, T. R. E., Lawrie, S. M., Husain, N., Dazzan, P., Deakin, B., Shannon Weickert, C. & Upthegrove, R., 7 Jul 2023, (E-pub ahead of print) In: Brain, Behavior, and Immunity. 113, p. 166-175 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression
Jauhar, S., Arnone, D., Baldwin, D. S., Bloomfield, M., Browning, M., Cleare, A. J., Corlett, P., Deakin, J. F. W., Erritzoe, D., Fu, C., Fusar-Poli, P., Goodwin, G. M., Hayes, J., Howard, R., Howes, O. D., Juruena, M. F., Lawrie, S. M., McAllister-Williams, H., Marwaha, S., Matuskey, D., & 14 others, 16 Jun 2023, (E-pub ahead of print) In: Molecular Psychiatry.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile -
Keeping up with the kids: the value of co-production in the study of irritability in youth depression and its underlying neural circuitry
Macsweeney, N., Louvet, P., Zafar, S., Chan, S. W. Y., Kwong, A. S. F., Lawrie, S. M., Romaniuk, L. & Whalley, H. C., 15 Jun 2023, In: Frontiers in Behavioral Neuroscience. 17Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The association between peripheral inflammation, brain glutamate and antipsychotic response in Schizophrenia: Data from the STRATA collaboration
Fenn-Moltu, S., Deakin, B., Drake, R., Howes, O. D., Lawrie, S. M., Lewis, S., Nikkheslat, N., Walters, J. T. R., MacCabe, J. H., Mondelli, V. & Egerton, A., 12 May 2023, (E-pub ahead of print) In: Brain, Behavior, and Immunity. 111, p. 343-351 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
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Visit from the Chief Medical Officer of Scotland
Matthew Iveson (Contributor), Andrew McIntosh (Host), Iona Beange (Contributor), Elizabeth Kirkham (Contributor), Mat Harris (Contributor), Carys Pugh (Contributor), Sue Fletcher-Watson (Contributor), Robert Stewart (Contributor), Stephen Lawrie (Contributor), Colin Buchanan (Contributor), Peter W Mathieson (Chair), David Porteous (Contributor), James Boardman (Contributor) & Angus Macbeth (Contributor)
16 Jan 2020Activity: Participating in or organising an event types › Public Engagement – Festival/Exhibition
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Out of sight, Out of Mind
Stephen Lawrie (Invited speaker)
31 Oct 2019Activity: Participating in or organising an event types › Public Engagement – Festival/Exhibition
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Imaging of people at high of bipolar disorder and schizophrenia
Stephen Lawrie (Invited speaker)
4 Jul 2019Activity: Academic talk or presentation types › Invited talk
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Early developmental and multivariate analyses of brain structure predict schizophrenia in the Edinburgh High Risk Study
Stephen Lawrie (Invited speaker)
6 Jun 2019Activity: Academic talk or presentation types › Invited talk
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Visit from the Scottish Government's Cabinet Secretary for Health and Sport
Andrew McIntosh (Host), Iona Beange (Contributor), Matthew Iveson (Contributor), Elizabeth Kirkham (Contributor), Mathew Harris (Contributor), Carys Pugh (Contributor), Susan Fletcher-Watson (Contributor), Robert Stewart (Contributor), Stephen Lawrie (Advisor), Colin Buchanan (Contributor) & Jonathan Seckl (Chair)
9 Jul 2019Activity: Participating in or organising an event types › Public Engagement – Festival/Exhibition
File
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Psychosis Recovery Orientation in Malawi by Improving Services and Engagement
Lawrie, S., Allardyce, J., Jain, S., Macbeth, A., McIntosh, A. & Pickersgill, M.
1/03/22 → 28/02/27
Project: Research
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1 Pathway - focussed polygenic and gene expression risk scores for schizophrenia and impact on brain structure across the lifespan
Barbu, M. C., Lawrie, S. & Whalley, H.
1/06/22 → 31/05/23
Project: Research
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The impact of pathway-focussed polygenic and gene expression risk scores for schizophrenia on brain structure across the lifespan
Barbu, M. C., Lawrie, S. & Whalley, H.
1/06/21 → 31/05/22
Project: Research
Datasets
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A Celebration of Scottish Health Cohort Studies: Participants' attitudes towards data research
Beange, I. (Creator), McIntosh, A. (Creator), Kirkham, E. (Creator), Fletcher-Watson, S. (Creator), Lawrie, S. (Creator), Batty, G. D. (Creator), Boardman, J. (Creator), Black, C. (Creator) & Porteous, D. (Creator), Edinburgh DataShare, 16 Dec 2019
DOI: 10.7488/ds/2728
Dataset
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Views on sharing mental and physical health data among people with and without experience of mental illness
Fletcher-Watson, S. (Creator), Beange, I. (Creator), Chan, S. (Creator), McIntosh, A. (Creator), Kirkham, E. (Creator), Lawrie, S. (Creator), Crompton, C. (Creator) & Iveson, M. (Creator), Edinburgh DataShare, 11 Jul 2022
DOI: 10.7488/ds/3486, https://www.medrxiv.org/content/10.1101/2021.02.02.21251041v1
Dataset
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Data from: Use of novel psychoactive substances by inpatients on general adult psychiatric wards
Stanley, J. L. (Creator), Mogford, D. V. (Creator), Lawrence, R. J. (Creator) & Lawrie, S. (Creator), Dryad, 4 Jan 2016
DOI: 10.5061/dryad.gp545, http://datadryad.org/stash/dataset/doi:10.5061/dryad.gp545
Dataset
Press/Media
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Hollywood past saves climber given dementia death sentence
22/02/19 → 23/02/19
2 Media contributions
Press/Media: Expert Comment
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Hiring people with schizophrenia benefits both patients and companies, says Prof Stephen Lawrie (Psychiatry)
1/02/17
1 item of Media coverage
Press/Media: Expert Comment
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Review of Professor Stephen Lawrie at the Edinburgh Fringe Festival 2016
28/09/16
1 Media contribution
Press/Media: Public Engagement Activities
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Professor Stephen Lawrie says finds men find it difficult to gauge how women will respond to chat-up lines
5/09/13
1 item of Media coverage
Press/Media: Research
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Professor Stephen Lawrie says men can't read human emotions as well as women
5/04/13
1 item of Media coverage
Press/Media: Research