Projects per year
Search results
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Active
Spatiotemporal Profiling of Vascular Cell Transcriptomes in Alzheimer’s Disease
McQuaid, C. (Principal Investigator), Hasel, P. (Co-investigator), Montagne, A. (Co-investigator) & Spires-Jones, T. (Co-investigator)
UK Dementia Research Institute Ltd
1/04/25 → 31/03/26
Project: Research
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Unmasking neuromodulatory control of locomotion
Spires-Jones, T. (Principal Investigator)
16/08/24 → 31/05/27
Project: Research
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Targeting Synaptic ingestion by astrocytes in Alzheimer’s disease
Spires-Jones, T. (Principal Investigator) & Durrant, C. (Co-investigator)
UK Dementia Research Institute Ltd
1/05/24 → 30/04/26
Project: Research
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Understanding and preventing synaptic spread of tau
Spires-Jones, T. (Principal Investigator), Diaz-Castro, B. (Co-investigator) & Durrant, C. (Co-investigator)
1/03/24 → 31/08/27
Project: Research
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Mechanisms of tau pathology progression in primary tauopathy
Durrant, C. (Principal Investigator) & Spires-Jones, T. (Co-investigator)
1/07/22 → 30/09/26
Project: Research
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Mechanisms of tau pathology progression in primary tauopathy
Durrant, C. (Principal Investigator) & Spires-Jones, T. (Co-investigator)
1/07/22 → 30/06/25
Project: Research
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UKDRI QQR - 1/4/23-31/3/28
Hardingham, G. (Principal Investigator), Bowles, K. (Co-investigator), Bowles, K. (Co-investigator), Chandran, S. (Co-investigator), Chandran, S. (Co-investigator), Diaz-Castro, B. (Co-investigator), Diaz-Castro, B. (Co-investigator), Gan, J. (Co-investigator), Gan, J. (Co-investigator), Hunt, D. (Co-investigator), Hunt, D. (Co-investigator), McColl, B. (Co-investigator), McColl, B. (Co-investigator), Montagne, A. (Co-investigator), Montagne, A. (Co-investigator), Opazo, P. (Co-investigator), Priller, J. (Co-investigator), Priller, J. (Co-investigator), Spires-Jones, T. (Co-investigator), Spires-Jones, T. (Co-investigator), Wardlaw, J. (Co-investigator) & Wardlaw, J. (Co-investigator)
UK Dementia Research Institute Ltd
1/07/22 → 31/03/28
Project: Research
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Pre-competitive Analytical Validation of SV2A PET as a Biomarker of Synaptic Density (SV2A Project)
Spires-Jones, T. (Principal Investigator)
29/03/22 → 28/03/28
Project: Research
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Pre-competitive Analytical Validation of SV2A PET as a Biomarker of Synaptic Density (SV2A Project)
Spires-Jones, T. (Principal Investigator)
FNIH: The Foundation for the National Institutes of Health
29/03/22 → 28/03/28
Project: Research
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MS Society Edinburgh Centre for MS Research 2021
Lyons, D. (Principal Investigator), Hardingham, G. (Co-investigator) & Spires-Jones, T. (Co-investigator)
1/01/21 → 31/12/25
Project: Research
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The role of tau in synapse survival and its relevance to Alzheimer�s disease
Spires-Jones, T. (Principal Investigator)
1/09/19 → 30/09/25
Project: Research
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Finished
Investigating the association between astrocyte reactivity and BBB dysfunction in human tauopathies
Spires-Jones, T. (Principal Investigator)
1/11/24 → 30/04/25
Project: Research
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CT1812 effect on potential Aβ-TMEM97 synaptic interaction
Spires-Jones, T. (Principal Investigator)
1/05/22 → 31/05/22
Project: Research
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Identifying therapeutic strategies for cognitive health in disease via oligodendrocyte targeting
Miron, V. (Principal Investigator), Hardingham, G. (Co-investigator) & Spires-Jones, T. (Co-investigator)
4/04/22 → 28/02/25
Project: Research
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Collaborative pump priming award ¿ ARUK Scotland Network Centre Grant
Toombs, J. (Principal Investigator) & Spires-Jones, T. (Co-investigator)
1/04/22 → 31/03/23
Project: Research
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Collaborative pump priming award � ARUK Scotland Network Centre Grant
Meftah, S. (Principal Investigator), Gan, J. (Co-investigator), Horsburgh, K. (Co-investigator), McColl, B. (Co-investigator), Spires-Jones, T. (Co-investigator), Szymkowiak, S. (Co-investigator) & Toombs, J. (Co-investigator)
ARUK East Central Scotland Network Centre
1/04/22 → 31/03/23
Project: Research
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ECAT-Plus ¿ Rob McGeachan ¿ Mechanisms underpinning the propagation of pathological tau in tauopathies
Whyte, M. (Principal Investigator), Gilbert, N. (Co-investigator), Henderson, N. (Co-investigator), Jackson, A. (Co-investigator), Spires-Jones, T. (Co-investigator) & Walmsley, S. (Co-investigator)
1/08/21 → 31/07/24
Project: Research
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ECAT-Plus � Rob McGeachan � Mechanisms underpinning the propagation of pathological tau in tauopathies
Spires-Jones, T. (Principal Investigator), Gilbert, N. (Co-investigator), Henderson, N. (Co-investigator), Jackson, A. (Co-investigator), Walmsley, S. (Co-investigator) & Whyte, M. (Co-investigator)
1/08/21 → 31/07/24
Project: Research
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Array tomography on mouse brain samples
Spires-Jones, T. (Principal Investigator)
Non-EU industry, commerce and public corporations
5/01/21 → 5/06/21
Project: Research
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CoEN5025 NANOSYN: Unravelling synaptic pathology in Alzheimer's disease and Dementia with Lewy bodies using super-resolution microscopy
Spires-Jones, T. (Principal Investigator) & Horrocks, M. (Co-investigator)
15/08/20 → 13/11/23
Project: Research
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CoEN5025 NANOSYN: Unravelling synaptic pathology in Alzheimer's disease and Dementia with Lewy bodies using super-resolution microscopy
Spires-Jones, T. (Principal Investigator) & Horrocks, M. (Co-investigator)
15/08/20 → 14/08/22
Project: Research
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The role of tau in synapse survival and its relevance to Alzheimer¿s disease
Spires-Jones, T. (Principal Investigator)
1/09/19 → 31/08/24
Project: Research
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Elucidating the effects of modulating a novel target on synapse loss in models of plaque deposition and Abeta-mediated toxicity
Spires-Jones, T. (Principal Investigator)
1/04/19 → 30/04/21
Project: Research
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Synaptic resilience in ageing
Spires-Jones, T. (Principal Investigator)
Non-EU industry, commerce and public corporations
1/04/19 → 20/12/21
Project: Research
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The effect of APOE genotype on microglial-mediated synapse phagocytosis in Alzheimer¿s disease
Spires-Jones, T. (Principal Investigator)
1/04/19 → 1/05/20
Project: Research
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Elucidating the effects of modulating a novel target on synapse loss in models of plaque deposition and Abeta-mediated toxicity
Spires-Jones, T. (Principal Investigator)
UK industry, commerce and public corporations
1/04/19 → 30/04/21
Project: Research
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Translational potential of targeting Kv3.4 in human neurons to prevent synapse degeneration
Spires-Jones, T. (Principal Investigator)
1/03/19 → 28/02/21
Project: Research
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Assessing the role of GABAergic interneurons in a mouse model of Alzheimer's disease
Spires-Jones, T. (Principal Investigator)
1/10/18 → 30/09/19
Project: Research
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Academic collaboration in Neurodegeneration - AbbVie/UoE
Spires-Jones, T. (Principal Investigator)
Non-EU industry, commerce and public corporations
1/09/18 → 31/12/21
Project: Research
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UK Dementia Research Institute
Spires-Jones, T. (Principal Investigator)
UK Dementia Research Institute Ltd
1/09/17 → 31/03/23
Project: Research
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UK Dementia Research Institute
Hardingham, G. (Principal Investigator), Chandran, S. (Co-investigator), McColl, B. (Co-investigator), Spires-Jones, T. (Co-investigator), Wardlaw, J. (Co-investigator) & Williams, A. (Co-investigator)
1/09/17 → 31/03/23
Project: Research
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Studying the amyloid cascade at synapses in a novel model of Alzheimer's disease
Spires-Jones, T. (Principal Investigator)
26/06/17 → 1/09/17
Project: Research
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Development and validation of tools for investigation tau propagation in early stage Alzheimers disease
Oren, I. (Principal Investigator), Nolan, M. (Co-investigator) & Spires-Jones, T. (Co-investigator)
9/05/17 → 8/08/18
Project: Research
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Synaptic Proteins that engage Amyloid Beta in the human brain
Spires-Jones, T. (Principal Investigator), Chandran, S. (Co-investigator) & Smith, C. (Co-investigator)
1/03/17 → 14/08/20
Project: Research
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ALZSYN: Imaging synaptic contributors to dementia
Spires-Jones, T. (Principal Investigator)
1/11/16 → 30/04/22
Project: Research
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ALZSYN: Imaging synaptic contributors to dementia
Spires-Jones, T. (Principal Investigator)
1/11/16 → 30/04/22
Project: Research
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Development and validation of tools for investigating tau propagation in early stage Alzheimer¿s disease
Oren, I. (Principal Investigator), Nolan, M. (Co-investigator) & Spires-Jones, T. (Co-investigator)
5/09/16 → 31/05/19
Project: Research
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Studying the amyloid cascade hypothesis in a novel model of Alzheimer's disease
Spires-Jones, T. (Principal Investigator)
18/07/16 → 11/09/16
Project: Research
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Expanding novel imaging capability to investigate synapse degeneration in Alzheimer's disease
Spires-Jones, T. (Principal Investigator)
1/04/16 → 31/03/19
Project: Research
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Vacation scholarship for Jee Soo (Monica) Kim
Spires-Jones, T. (Principal Investigator)
19/05/14 → 31/12/14
Project: Research
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Mechanisms of tau-induced in synapse loss in Alzheimer¿s disease
Spires-Jones, T. (Principal Investigator)
1/02/14 → 31/01/17
Project: Research
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Targeting tau to prevent Abeta mediated synapse degeneration in Alzheimer's
Spires-Jones, T. (Principal Investigator), Hardt, O. (Co-investigator) & Oren, I. (Co-investigator)
1/11/13 → 31/10/17
Project: Research