Research output per year
Research output per year
Personal profile
Research Interests
The Wt1+ mesothelium contributes to the hepatic stellate cell population during development, and after fibrotic liver injury in the subcapsular region; loss of Wt1 also influences liver parenchymal development. We aim to characterise the role of Wt1 in hepatic stellate cells in fibrotic and non-fibrotic liver injury and regeneration.
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Collaborations and top research areas from the last five years
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A TGFβ-ECM-Integrin signalling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease
Waddell, S., Yao, Y., Olaizola, P., Walker, A., Jarman, E., Gournopanos, K., Gradinaru, A., Christodoulou, E., Gautier, P., Boerrigter, M. M., Cadamuro, M., Fabris, L., Drenth, J. P., Kendall, T. J., Banales, J. M., Khamseh, A., Mill, P. & Boulter, L., 13 Sept 2023, In: Science Translational Medicine.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach
Brennan, P. N., Elsharkawy, A. M., Kendall, T. J., Loomba, R., Mann, D. A. & Fallowfield, J. A., 2 Jun 2023, In: Nature Reviews Gastroenterology & Hepatology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Intestinal B-cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling
Kotsiliti, E., Leone, V., Schuehle, S., Govaere, O., Li, H., Wolf, M. J., Horvatic, H., Bierwirth, S., Hundertmark, J., Inverso, D., Zizmare, L., Sarusi-Portuguez, A., Gupta, R., O'Connor, T., Giannou, A. D., Shiri, A. M., Schlesinger, Y., Beccaria, M. G., Rennert, C., Pfister, D., & 52 others, 9 May 2023, (E-pub ahead of print) In: Journal of Hepatology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential
Carlessi, R., Denisenko, E., Boslem, E., Köhn-Gaone, J., Main, N., Abu bakar, N. D. B., Shirolkar, G. D., Jones, M., Beasley, A. B., Poppe, D., Dwyer, B. J., Jackaman, C., Tjiam, M. C., Lister, R., Karin, M., Fallowfield, J. A., Kendall, T. J., Forbes, S. J., Gray, E. S., Olynyk, J. K., & 5 others, 13 Apr 2023, In: Cell Genomics. p. 100301 100301.Research output: Contribution to journal › Article › peer-review
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Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance
CCA Model Consortium, Calvisi, D. F., Boulter, L., Vaquero, J., Saborowski, A., Fabris, L., Rodrigues, P., Coulouarn, C., Castro, R. E., Segatto, O., Raggi, C., van der Laan, L. J. W., Carpino, G., Goeppert, B., Roessler, S., Kendall, T. J., Evert, M., Gonzalez-Sanchez, E., Valle, J. W., Vogel, A., & 16 others, 8 Feb 2023, (E-pub ahead of print) In: Nature Reviews Gastroenterology & Hepatology.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Hepatica: Quantifying liver health in surgical candidates for liver malignancies
Mole, D., Fallowfield, J., Garden, J., Kendall, T., Kendall, T., Semple, S. & Wigmore, S.
UK central government bodies/local authorities, health and hospital authorities
1/02/17 → 31/03/19
Project: Research
Datasets
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Whole slide images of armadillo liver from M.leprae dataset
Kendall, T. (Creator) & Rambukkana, A. (Creator), Edinburgh DataShare, 31 Mar 2023
DOI: 10.7488/ds/3147
Dataset