Timothy Kendall

Phone0131 242 6655
EmailTim.Kendalled.acuk

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Research Interests

The Wt1+ mesothelium contributes to the hepatic stellate cell population during development, and after fibrotic liver injury in the subcapsular region; loss of Wt1 also influences liver parenchymal development. We aim to characterise the role of Wt1 in hepatic stellate cells in fibrotic and non-fibrotic liver injury and regeneration.

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Division of Pathology

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59 Article
4 Meeting abstract
2 Review article
1 Chapter (peer-reviewed)
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- 1 Paper

Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance
CCA Model Consortium, Calvisi, D. F., Boulter, L., Vaquero, J., Saborowski, A., Fabris, L., Rodrigues, P., Coulouarn, C., Castro, R. E., Segatto, O., Raggi, C., van der Laan, L. J. W., Carpino, G., Goeppert, B., Roessler, S., Kendall, T. J., Evert, M., Gonzalez-Sanchez, E., Valle, J. W., Vogel, A., & 16 othersBridgewater, J., Borad, M. J., Gores, G. J., Roberts, L. R., Marin, J. J. G., Andersen, J. B., Alvaro, D., Forner, A., Banales, J. M., Cardinale, V., Macias, R. I. R., Vicent, S., Chen, X., Braconi, C., Verstegen, M. M. A. & Fouassier, L., 8 Feb 2023, (E-pub ahead of print) In: Nature Reviews Gastroenterology & Hepatology.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene
Kentistou, K., Luan, J., Wittemans, L. B. L., Hambly, C., Klaric, L., Kutalik, Z., Speakman, J. R., Wareham, N. J., Kendall, T. J., Langenberg, C., Wilson, J. F., Joshi, P. K. & Morton, N. M., 19 Jan 2023, In: Nature Communications.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage
Ferreira-Gonzalez, S., Man, T. Y., Esser, H., Aird, R., Kilpatrick, A., Rodrigo Torres, D., Younger, N., Campana, L., Gadd, V., Dwyer, B., Aleksieva, N., Boulter, L., Macmillan, M., Wang, Y., Mylonas, K. J., Ferenbach, D. A., Kendall, T. J., Lu, W-Y., Acosta, J. C., Kurian, D., & 5 othersO'Neill, S., Oniscu, G., Banales, J. M., Krimpenfort, P. & Forbes, S. J., 7 Dec 2022, In: Science Translational Medicine. 14, 674, 16 p., eabj4375.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Assessment of clinical trial protocols for pathology content using the SPIRIT-Path guidelines highlights areas for improvement
Robinson, P., Bacon, C. M., Lim, S. J., Shaaban, A. M., Brierley, D., Lewis, I., Harrison, D., Kendall, T. J. & Robinson, M., 5 Aug 2022, In: Journal of Pathology: Clinical Research. 8, 5, p. 411-421
Research output: Contribution to journal › Article › peer-review

Open Access
File
Role of Hepatocyte Senescence in the Activation of Hepatic Stellate Cells and Liver Fibrosis Progression
Wijayasiri, P., Astbury, S., Kaye, P., Oakley, F., Alexander, G. J., Kendall, T. J. & Aravinthan, A. D., 17 Jul 2022, In: Cells. 11, 14, 2221.
Research output: Contribution to journal › Article › peer-review

Open Access
File

1 Active
3 Finished

Defining the oxidative stress-related mechanisms by which activation of the transcription factor Nrf2 arrests and resolves liver fibrosis
Henderson, N., Kendall, T. & Walsh, T.
MRC
1/06/20 → 31/12/23
Project: Research
Development of an integrated precision AI tool for the stratification of non-alcoholic fatty liver disease (INTErPRET-NAFLD)
Kendall, T. & Fallowfield, J.
UK central government bodies/local authorities, health and hospital authorities
1/10/20 → 30/09/22
Project: Research
SteatoSITE - an integrated gene-to-patient data commons for NAFLD research
Fallowfield, J. & Kendall, T.
UK central government bodies/local authorities, health and hospital authorities
1/07/18 → 31/03/21
Project: Research
Hepatica: Quantifying liver health in surgical candidates for liver malignancies
Mole, D., Fallowfield, J., Garden, J., Kendall, T., Kendall, T., Semple, S. & Wigmore, S.
UK central government bodies/local authorities, health and hospital authorities
1/02/17 → 31/03/19
Project: Research

Whole slide images of armadillo liver from M.leprae dataset
Kendall, T. (Creator) & Rambukkana, A. (Creator), Edinburgh DataShare, 31 Mar 2023
DOI: 10.7488/ds/3147
Dataset

Timothy Kendall

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Dive into details

Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance

Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage

Assessment of clinical trial protocols for pathology content using the SPIRIT-Path guidelines highlights areas for improvement

Role of Hepatocyte Senescence in the Activation of Hepatic Stellate Cells and Liver Fibrosis Progression

Defining the oxidative stress-related mechanisms by which activation of the transcription factor Nrf2 arrests and resolves liver fibrosis

Development of an integrated precision AI tool for the stratification of non-alcoholic fatty liver disease (INTErPRET-NAFLD)

SteatoSITE - an integrated gene-to-patient data commons for NAFLD research

Hepatica: Quantifying liver health in surgical candidates for liver malignancies

Whole slide images of armadillo liver from M.leprae dataset

Timothy Kendall

Personal profile

Research Interests

Websites

Fingerprint

Network

Research output

Projects

Datasets