Timothy Walsh

2024

Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury

HEMOTION Trial Investigators on behalf of the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group, and the Canadian Traumatic Brain Injury Research Consortium, Turgeon, A. F., Fergusson, D. A., Clayton, L., Patton, M-P., Neveu, X., Walsh, T. S., Docherty, A., Malbouisson, L. M., Pili-Floury, S., English, S. W., Zarychanski, R., Moore, L., Bonaventure, P. L., Laroche, V., Verret, M., Scales, D. C., Adhikari, N. K. J., Greenbaum, J., Kramer, A., & 35 othersRey, V. G., Ball, I., Khwaja, K., Wise, M., Harvey, D., Lamontagne, F., Chabanne, R., Algird, A., Krueper, S., Pottecher, J., Zeiler, F., Rhodes, J., Rigamonti, A., Burns, K. E. A., Griesdale, D. E., Sisconetto, L. S., Kutsogiannis, D. J., Roger, C., Green, R., Boyd, J. G., Wright, J., Charbonney, E., Nair, P., Astles, T., Sy, E., Hébert, P. C., Chassé, M., Gomez, A., Ramsay, T., Taljaard, M., Fox-Robichaud, A., Tinmouth, A., St-Onge, M., Costerousse, O. & Lauzier, F., 22 Aug 2024, In: New England Journal of Medicine. 391, 8, p. 722-735 14 p.

Research output: Contribution to journal › Article › peer-review

Multimorbidity and adverse outcomes following emergency department attendance: population based cohort study

Blayney, M. C., Reed, M. J., Masterson, J., Anand, A., Bouamrane, M-M., Fleuriot, J. D., Luz, S., Lyall, M., Mercer, S. W., Mills, N. L., Shenkin, S. D., Walsh, T. S., Wild, S. H., Wu, H., McLachlan, S., Guthrie, B. & Lone, N. I., 17 Aug 2024, In: BMJ Medicine. 3, 1, 14 p., e000731.

Research output: Contribution to journal › Article › peer-review

Open Access

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Albumin Versus Balanced Crystalloid for the Early Resuscitation of Sepsis: An Open Parallel-Group Randomized Feasibility Trial. The ABC-Sepsis Trial

Albumin, Balanced, and Crystalloid-Sepsis (ABC-Sepsis) Investigators, Gray, A. J., Oatey, K., Grahamslaw, J., Irvine, S., Cafferkey, J., Kennel, T., Norrie, J., Walsh, T., Lone, N. I., Horner, D., Appelboam, A., Hall, P., Skipworth, R. J. E., Bell, D., Rooney, K., Shankar-Hari, M. & Corfield, A., 24 Jun 2024, (E-pub ahead of print) In: Critical Care Medicine.

Research output: Contribution to journal › Article › peer-review

Accelerometry to monitor physical activity following hospital discharge in critical illness survivors: a feasibility study

Ospanov, B., Walsh, T. S. & Griffith, D. M., 20 Jun 2024.

Research output: Contribution to conference › Poster › peer-review

Measuring the impact of maternal critical care admission on short- and longer-term maternal and birth outcomes

Masterson, J., Adamestam, I., Beatty, M., Boardman, J. P., Chislett, L., Johnston, P., Joss, J., Lawrence, H., Litchfield, K., Plummer, N., Rhode, S., Walsh, T. S., Wise, A., Wood, R., Weir, C. J. & Lone, N. I., 7 Jun 2024, In: Intensive Care Medicine. 50, p. 890-900 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Vibration Therapy – a new buzzword for treating ICU-acquired weakness

Walsh, T. S., 1 Jun 2024, In: Critical Care Medicine. 52, 6, p. 984-986 3 p.

Research output: Contribution to journal › Editorial › peer-review

Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): Protocol for a mixed methods process evaluation of a randomised controlled trial

Aitken, L. M., Emerson, L. M., Kydonaki, K., Blackwood, B., Creagh-Brown, B., Lone, N. I., McKenzie, C., Reade, M. C., Weir, C. J., Wise, M. P. & Walsh, T. S., 5 Apr 2024, In: BMJ Open. 14, 4, 7 p., e081637.

Research output: Contribution to journal › Article › peer-review

Open Access

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Ergometer based cardiopulmonary exercise test in critical illness survivors: a systematic review

Ospanov, B., Bakker-Dyos, J., Walsh, T. S. & Griffith, D. M., 7 Mar 2024.

Research output: Contribution to conference › Poster › peer-review

2023

Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): Protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the United Kingdom

Walsh, T. S., Aitken, L. M., McKenzie, C., Boyd, J., Macdonald, A., Giddings, A., Hope, D., Norrie, J., Weir, C. J., Parker, R. A., Lone, N. I., Emerson, L. M., Kydonaki, K., Creagh-Brown, B., Morris, S., McAuley, D. F., Dark, P., Wise, M. P., Gordon, A. C., Perkins, G. D., & 5 othersReade, M. C., Blackwood, B., MacLullich, A. M. J., Glen, R. & Page, V. J., 10 Dec 2023, In: BMJ Open. 13, 12, 11 p., e078645.

Research output: Contribution to journal › Article › peer-review

Open Access

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Do critical illness survivors with multimorbidity need a different model of care?

Stewart, J., Bradley, J., Smith, S., McPeake, J., Walsh, T., Haines, K., Leggett, N., Hart, N. & McAuley, D., 8 Dec 2023, In: Critical Care. 27, 1, p. 485

Research output: Contribution to journal › Review article › peer-review

Open Access

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Delivery of a novel intervention to facilitate liberation from mechanical ventilation in paediatric intensive care: a process evaluation.

Jordan, J., Tume, L. N., Clarke, M., McAuley, D. F., McDowell, C., McIlmurray, L., Morris, K. P., Peters, M. J., Walsh, T. S. & Blackwood, B., 27 Nov 2023, In: PLoS ONE. 18, 11, 17 p., e0293063.

Research output: Contribution to journal › Article › peer-review

Open Access

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Guidance to inform research recruitment processes for studies involving critically ill patients

Woolfall, K., Paddoack, K., Watkins, M., Kearney, A., Neville, K., Frith, L., Welters, I. D., Gamble, C., Trinder, J., Pattison, N., White, C., Brett, S., Dilworth, S., Ross, M., Mouncey, P. R., Rowan, K., Dawson, A., Collet, C., Walsh, T. S. & Young, B., 8 Sept 2023, (E-pub ahead of print) In: Journal of the Intensive Care Society. 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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A second update on mapping the human genetic architecture of COVID-19

The COVID-19 Host Genetics Initiative, 6 Sept 2023, In: Nature. 621, 7977, p. E7-E26

Research output: Contribution to journal › Article › peer-review

Open Access

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Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

GenOMICC Investigators, Law, A., Hendry, S. C. & Baillie, J. K., 27 Jul 2023, In: Nature. 619, 7971, p. E61

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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Recovery from Covid-19 critical illness: a secondary analysis of the ISARIC4C CCP-UK cohort study and the RECOVER trial

ISARIC4C and RECOVER Investigators, Pauley, E., Drake, T. M., Griffith, D. M., Lone, N. I., Harrison, E. M., Baillie, J. K., Scott, J. T., Walsh, T. S., Semple, M. G. & Docherty, A. B., 1 May 2023, In: Journal of the Intensive Care Society. 24, 2, p. 162-169 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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GWAS and meta-analysis identifies 49 genetic variants underlying critical Covid-19

GenOMICC Investigators, SCOURGE Consortium, ISARIC4C Investigators, 23andMe Covid-19 Team, Pairo-Castineira, E., Rawlik, K., Bretherick, A. D., Qi, T., Wu, Y., Nassiri, I., McConkey, G. A., Zechner, M., Klaric, L., Griffiths, F., Oosthuyzen, W., Kousathanas, A., Richmond, A., Millar, J., Russell, C. D., Malinauskas, T., & 39 othersThwaites, R., Morrice, K., Keating, S., Maslove, D. M., Nichol, A. D., Semple, M. G., Knight, J., Shankar-Hari, M., Summers, C., Hinds, C., Horby, P., Ling, L., McAuley, D. F., Montgomery, H., Openshaw, P. J. M., Begg, C., Walsh, T. S., Tenesa, A., Flores, C., Riancho, J. A., Rojas-Martinez, A., Lapunzina, P., Yang, J., Ponting, C. P., Wilson, J. F., Vitart, V., Abedalthagafi, M. S., Luchessi, A., Parra, E. J., Cruz, R., Carracedo, A., Fawkes, A., Murphy, L., Rowan, K., Pereira, A. C., Law, A., Fairfax, B. P., Clohisey Hendry, S. & Baillie, J. K., May 2023, In: Nature. 617, 7962, p. 764-768 30 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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biomArker-guided Duration of Antibiotic treatment in hospitalised Patients with suspecTed Sepsis (ADAPT-Sepsis): A protocol for a multicentre randomised controlled trial

Dark, P., Perkins, G. D., McMullan, R., McAuley, D., Gordon, A. C., Clayton, J., Mistry, D., Young, K., Regan, S., McGowan, N., Stevenson, M., Gates, S., Carlson, G. L., Walsh, T., Lone, N. I., Mouncey, P. R., Singer, M., Wilson, P., Felton, T., Marshall, K., & 2 othersHossain, A. M. & Lall, R., 25 Apr 2023, (E-pub ahead of print) In: Journal of the Intensive Care Society. 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2022

Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis)

Scott, J., Trevi, L., McNeil, H., Ewen, T., Mawson, P., McDonald, D., Filby, A., Lall, R., Booth, K., Boschman, G., Melkebeek, V., Perkins, G., McMullan, R., McAuley, D. F., McCullagh, I. J., Walsh, T., Rostron, A., Shankar-Hari, M., Dark, P., Simpson, A. J., & 2 othersConway Morris, A. & Hellyer, T. P., 9 Dec 2022, In: BMJ Open. 12, 12, p. e068321

Research output: Contribution to journal › Article › peer-review

Open Access

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Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol

HEMOTION Trial Team, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group and the Canadian Traumatic Brain Injury Research Consortium, 10 Oct 2022, In: BMJ Open. 12, 10, p. e067117 e067117.

Research output: Contribution to journal › Article › peer-review

Open Access

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Outcomes from COVID-19 clinical trials in hospitalised patients: seeking the truth that matters

Griffith, D. M. & Walsh, T. S., 15 Sept 2022, In: American Journal of Respiratory and Critical Care Medicine. 206, 6, p. 658-660

Research output: Contribution to journal › Article › peer-review

Open Access

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Outcomes from COVID-19 Clinical Trials in Hospitalized Patients: Seeking the Truth That Matters

Griffith, D. M. & Walsh, T. S., 15 Sept 2022, In: American Journal of Respiratory and Critical Care Medicine. 206, 6, p. 658-660

Research output: Contribution to journal › Editorial › peer-review

Open Access

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Severe maternal morbidity in Scotland

Masterson, J., Adamestam, I., Beatty, M., Boardman, J. P., Johnston, P., Joss, J., Lawrence, H., Litchfield, K., Walsh, T. S., Wise, A., Wood, R., Weir, C. J., Denison, F. C. & Lone, N. I., 1 Sept 2022, In: Anaesthesia: Peri-operative medicine, critical care and pain. 77, 9, p. 971-980

Research output: Contribution to journal › Article › peer-review

Open Access

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An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial

Gaughan, E. E., Quinn, T. M., Mills, A., Bruce, A. M., Antonelli, J., Mackinnon, A., Aslanis, V., Li, F., O'connor, R., Boz, C., Mills, R., Emanuel, P., Burgess, M., Rinaldi, G., Valanciute, A., Mills, B., Scholefield, E., Hardisty, G., Gwyer Findlay, E., Parker, R. A., & 19 othersNorrie, J., Dear, J. W., Akram, A. R., Koch, O., Templeton, K., Dockrell, D. H., Walsh, T. S., Partridge, S., Humphries, D., Wang-jairaj, J., Slack, R. J., Schambye, H., Phung, D., Gravelle, L., Lindmark, B., Shankar-Hari, M., Hirani, N., Sethi, T. & Dhaliwal, K., 16 Aug 2022, (E-pub ahead of print) In: American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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Whole genome sequencing reveals host factors underlying critical Covid-19

GenOMICC Investigators, Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., & 57 othersZechner, M., Parkinson, N., Siddiq, A., Goddard, P., Donovan, S., Maslove, D., Nichol, A., Semple, M. G., Zainy, T., Maleady-Crowe, F., Todd, L., Salehi, S., Knight, J., Elgar, G., Chan, G., Arumugam, P., Patch, C., Rendon, A., Bentley, D., Kingsley, C., Kosmicki, J. A., Horowitz, J. E., Baras, A., Abecasis, G. R., Ferreira, M. A. R., Justice, A., Mirshahi, T., Oetjens, M., Rader, D. J., Ritchie, M. D., Verma, A., Fowler, T. A., Shankar-Hari, M., Summers, C., Hinds, C., Horby, P., Ling, L., McAuley, D., Montgomery, H., Openshaw, P. J. M., Elliott, P., Walsh, T., Tenesa, A., Fawkes, A., Murphy, L., Rowan, K., Ponting, C. P., Vitart, V., Wilson, J. F., Yang, J., Bretherick, A. D., Scott, R. H., Hendry, S. C., Moutsianas, L., Law, A., Caulfield, M. J. & Baillie, J. K., 7 Jul 2022, In: Nature. 607, p. 97-103

Research output: Contribution to journal › Article › peer-review

Open Access

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Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial

Tume, L. N., Blackwood, B., McAuley, D. F., Morris, K. P., Peters, M. J., Jordan, J., Walsh, T. S. & McIlmurray, L., 22 Jun 2022, In: Nursing in Critical Care. NICC12810.

Research output: Contribution to journal › Article › peer-review

Open Access

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Redefining Critical Illness

Maslove, D. M., Tang, B., Shankar-Hari, M., Lawler, P. R., Angus, D. C., Baillie, J. K., Baron, R. M., Bauer, M., Buchman, T. G., Calfee, C. S., dos Santos, C. C., Giamarellos-Bourboulis, E. J., Gordon, A., Kellum, J. A., Knight, J. C., Leligdowicz, A., McAuley, D. F., McLean, A. S., Menon, D. K., Meyer, N. J., & 19 othersMoldawer, L. L., Reddy, K., Reilly, J. P., Russell, J. K., Sevransky, J. E., Seymour, C. W., Shapiro, N. I., Singer, M., Summers, C., Sweeney, T. E., Thompson, T., Poll, T. V. D., Venkatesh, B., Walley, K. R., Walsh, T. S., War, L. B., Wong, H. R., Zsolt, Z. E. & Marshall, J. C., 17 Jun 2022, In: Nature Medicine. 28, p. 1141–1148 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Albumin versus balanced crystalloid for resuscitation in the treatment of sepsis: A protocol for a randomised controlled feasibility study, “ABC-Sepsis”

Cafferkey, J., Ferguson, A., Grahamslaw, J., Oatey, K., Norrie, J., Lone, N. I., Walsh, T. S., Horner, D., Appelboam, A., Hall, P. S., Skipworth, R., Bell, D., Rooney, K. D., Shankar-Hari, M., Corfield, A. & Gray, A., 30 May 2022, (E-pub ahead of print) In: Journal of the Intensive Care Society.

Research output: Contribution to journal › Article › peer-review

Open Access

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Does a screening checklist for complex health and social care needs have potential clinical usefulness for predicting unplanned hospital readmissions in intensive care survivors: development and prospective cohort study.

Walsh, T. S., Pauley, E., Donaghy, E., Thompson, J., Barclay, L., Parker, R. A., Weir, C. J. & Marple, J., 23 Mar 2022, In: BMJ Open. 12, 3, p. e056524

Research output: Contribution to journal › Article › peer-review

Open Access

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Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT

Blackwood, B., Morris, K. P., Jordan, J., McIImurray, L., Agus, A., Boyle, R., Clarke, M., Easter, C., Feltbower, R. G., Hemming, K., Macrae, D., McDowell, C., Murray, M., Parslow, R., Peters, M. J., Phair, G., Tume, L. N., Walsh, T. S. & McAuley, D. F., 15 Mar 2022, In: Health Technology Assessment. 26, 18

Research output: Contribution to journal › Article › peer-review

Open Access

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Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics

Quinn, T., Gaughan, E. E., Bruce, A., Antonelli, J., O'Connor, R. A., Li, F., McNamara, S., Koch, O., Mackintosh, C., Dockrell, D., Walsh, T., Blyth, K. G., Church, C., Schwarze, J., Boz, C., Valanciute, A., Burgess, M., Emanuel, P., Mills, B., Rinaldi, G., & 27 othersHardisty, G., Mills, R., Gwyer Findlay, E. L., Jabbal, S., Duncan, A., Plant, S., Marshall, A. D. L., Young, I., Russell, K., Scholefield, E., Nimmo, A. F., Nazarov, I. B., Churchill, G. C., McCullagh, J. S. O., Ebrahimi, K. H., Ferrett, C., Templeton, K. E., Rannard, S., Owen, A., Moore, A., Finlayson, K., Shankar-Hari, M., Akram, A. R., Parker, R. A., Dear, J. W., Hirani, N. & Dhaliwal, K., 10 Feb 2022, In: EBioMedicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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2021

Intravenous iron to treat anaemia following critical care: a multicentre feasibility randomised trial

INTACT Investigators, 3 Dec 2021, (E-pub ahead of print) In: British Journal of Anaesthesia.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study

Hurst, E., Mellanby, R., Handel, I., Griffith, D. M., Rossi, A. G., Walsh, T. S., Shankar-Hari, M., Dunning, J., Homer, N. Z. M., Denham, S., Devine, K., Holloway, A., Moore, S. C., Thwaites, R. S., Samanta, R. J., Summers, C., Hardwick, H. E., Oosthuyzen, W., Turtle, L., Semple, M. G., & 3 othersOpenshaw, P., Baillie, K. & Russell, C. D., 22 Oct 2021, (E-pub ahead of print) In: BMJ Open.

Research output: Contribution to journal › Article › peer-review

Open Access

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Physical Rehabilitation and Critical Illness

Pauley, E., Walsh, T. S. & Griffith, D. M., 20 Sept 2021, (E-pub ahead of print) In: Anaesthesia and Intensive Care Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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Effect of a sedation and ventilator liberation protocol vs usual care on duration of invasive mechanical ventilation in pediatric intensive care units: a randomized clinical trial

Blackwood, B., Tume, L. N., Morris, K. P., Clarke, M., McDowell, C., Hemming, K., Peters, M. J., McIlmurray, L., Jordan, J., Agus, A., Murray, M., Parslow, R., Walsh, T. S., Macrae, D., Easter, C., Feltbower, R. G. & McAuley, D. F., 3 Aug 2021, In: Journal of the American Medical Association. 326, 5, p. 401-410 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Resilience in survivors of critical illness: a scoping review of the published literature in relation to definitions, prevalence, and relationship to clinical outcomes

Pauley, E. & Walsh, T. S., 27 Jul 2021, In: Journal of the Intensive Care Society.

Research output: Contribution to journal › Article › peer-review

Open Access

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Comparing performance on the months of the year backwards test in hospitalised patients with delirium, dementia and no cognitive impairment: an exploratory study

Hasemann, W., Duncan, N., Clarke, C., Nouzova, E., Süßenbach, L. M., Keerie, C., Assi, V., Weir, C. J., Evans, J., Walsh, T. S., Wilson, E., Quasim, T., Middleton, D. G., Weir, A. J., Barnett, J. H., Stott, D. J., MacLullich, A. M. J. & Tieges, Z., 22 Jun 2021, In: European geriatric medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care

Al-omari, B., Mcmeekin, P., Allen, A. J., Akram, A. R., Graziadio, S., Suklan, J., Jones, W. S., Lendrem, B. C., Winter, A., Cullinan, M., Gray, J., Dhaliwal, K., Walsh, T. S. & Craven, T. H., 9 Jun 2021, (E-pub ahead of print) In: BMC pulmonary medicine. 21, 1

Research output: Contribution to journal › Article › peer-review

Open Access

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Inconsistent relationship between depth of sedation and intensive care outcome: systematic review and meta-analysis

Aitken, L. M., Kydonaki, K., Blackwood, B., Trahair, L. G., Purssell, E., Sekhon, M. & Walsh, T. S., 15 Apr 2021, In: Thorax. 7, 11, p. 1089-1098

Research output: Contribution to journal › Article › peer-review

Open Access

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Polypharmacy and emergency readmission to hospital after critical illness: a population-level cohort study

Turnbull, A., Donaghy, E., Salisbury, L., Ramsay, P., Rattray, J., Walsh, T. S. & Lone, N. I., 1 Feb 2021, In: British Journal of Anaesthesia. 126, 2, p. P415-422

Research output: Contribution to journal › Article › peer-review

Open Access

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Activated neutrophil fluorescent imaging technique for human lungs

Craven, T. H., Walton, T., Akram, A. R., Scholefield, E., Mcdonald, N., Marshall, A. D. L., Humphries, D. C., Mills, B., Campbell, T. A., Bruce, A., Mair, J., Dear, J. W., Newby, D. E., Hill, A. T., Walsh, T. S., Haslett, C. & Dhaliwal, K., 13 Jan 2021, In: Scientific Reports. 11, 1

Research output: Contribution to journal › Article › peer-review

Open Access

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2020

Genetic mechanisms of critical illness in Covid-19

The GenOMICC Investigators, The ISARIC4C Investigators, The Covid-19 Human Genetics Initiative, 23andMe Investigators, BRACOVID Investigators, Gen-COVID Investigators, Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A., Rawlik, K., Parkinson, N., Pasko, D., Walker, S., Richmond, A., Fourman, M. H., Law, A., Furniss, J., Gountouna, E., Wrobel, N., & 42 othersRussell, C. D., Moutsianas, L., Wang, B., Meynert, A. M., Yang, Z., Zhai, R., Zheng, C., Griffith, F., Oosthuyzen, W., Shih, B., Keating, S., Zechner, M., Haley, C. S., Porteous, D., Hayward, C., Knight, J., Summers, C., Shankar-Hari, M., Turtle, L., Ho, A., Hinds, C., Horby, P., Nichol, A., Maslove, D. M., Ling, L., Klenerman, P., McAuley, D. F., Montgomery, H. E., Walsh, T. S., Shen, X., Rowan, K., Fawkes, A., Murphy, L., Ponting, C. P., Tenesa, A., Caulfield, M., Scott, R., Openshaw, P., Semple, M. G., Vitart, V., Wilson, J. & Baillie, J. K., 11 Dec 2020, (E-pub ahead of print) In: Nature. n/a, n/a.

Research output: Contribution to journal › Article › peer-review

Open Access

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Genetic mechanisms of critical illness in Covid-19

Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A. D., Rawlik, K., Parkinson, N., Pasko, D., Walker, S., Richmond, A., Fourman, M. H., Law, A., Furniss, J., Gountouna, E., Wrobel, N., Russell, C. D., Moutsianas, L., Wang, B., Meynert, A. M., Yang, Z., Zhai, R., & 39 othersZheng, C., Griffith, F., Oosthuyzen, W., Shih, B., Keating, S., Zechner, M., Haley, C., Porteus, D. J., Hayward, C., Knight, J., Summers, C., Shankar-Hari, M., Turtle, L., Ho, A., Hinds, C., Horby, P., Nichol, A., Maslove, D. M., Ling, L., Klenerman, P., McAuley, D. F., Montgomery, H., Walsh, T. S., The GenOMICC Investigators, The ISARIC4C Investigators, The Covid-19 Human Genetics Initiative, Shen, X., Rowan, K., Fawkes, A., Murphy, L., Ponting, C. P., Tenesa, A., Caulfield, M., Scott, R., Openshaw, P. J. M., Semple, M. G., Vitart, V., Wilson, J. F. & Baillie, J. K., 25 Sept 2020, medRxiv.

Research output: Working paper

Response to physical rehabilitation and recovery trajectories following critical illness: individual participant data meta-analysis protocol

Jones, J. R. A., Berney, S., Berry, M. J., Files, D. C., Griffith, D. M., McDonald, L. A., Morris, P. E., Moss, M., Nordon-Craft, A., Walsh, T., Gordon, I. J., Karahalios, A., Puthucheary, Z. & Denehy, L., 4 May 2020, In: BMJ Open.

Research output: Contribution to journal › Article › peer-review

Open Access

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Could host response guide VAP treatment? No answer yet - Authors' reply

VAPRapid2 Investigators, Anderson, N. & Walsh, T., 1 May 2020, In: The Lancet Respiratory Medicine. 8, 5, p. e38

Research output: Contribution to journal › Letter › peer-review

Community prescribing of potentially nephrotoxic drugs and risk of acute kidney injury requiring renal replacement therapy in critically ill adults: a national cohort study

Tominey, S., Timmins, A., Lee, R., Walsh, T. & Lone, N., 13 Feb 2020, In: Journal of the Intensive Care Society. p. 175114371990009

Research output: Contribution to journal › Article › peer-review

Open Access

File

Ventilator-associated pneumonia surveillance using two methods

Craven, T. H., Wojcik, G., Mccoubrey, J., Brooks, O., Grant, E., Keating, S., Reilly, J., Laurenson, I. F., Kefala, K. & Walsh, T. S., 5 Feb 2020, In: Journal of Hospital Infection.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

Hellyer, T. P., McAuley, D. F., Walsh, T. S., Anderson, N., Conway Morris, A., Singh, S., Dark, P., Roy, A. I., Perkins, G. D., McMullan, R., Emerson, L. M., Blackwood, B., Wright, S. E., Kefala, K., O'Kane, C. M., Baudouin, S. V., Paterson, R. L., Rostron, A. J., Agus, A., Bannard-Smith, J., & 19 othersRobin, N. M., Welters, I. D., Bassford, C., Yates, B., Spencer, C., Laha, S. K., Hulme, J., Bonner, S., Linnett, V., Sonksen, J., Van Den Broeck, T., Boschman, G., Keenan, DW. J., Scott, J., Allen, A. J., Phair, G., Parker, J., Bowett, S. A. & Simpson, A. J., 1 Feb 2020, In: The Lancet Respiratory Medicine. 8, 2, p. 182-191

Research output: Contribution to journal › Article › peer-review

Open Access

File

2019

The effect of dexmedetomidine and clonidine on the inflammatory response in critical illness: a systematic review of animal and human studies

Flanders, C. A., Rocke, A. S., Edwardson, S. A., Baillie, J. K. & Walsh, T. S., 11 Dec 2019, In: Critical Care. 23, 1, p. 402

Research output: Contribution to journal › Article › peer-review

Open Access

File

Myocardial injury and anaemia in patients undergoing surgery for fractured neck of femur: An observational study

Chew, E., Ghaffar, S., Docherty, A. B., Lang, A., Dawson, H., Keerie, C., Ray, D. C., White, T. O., MacLullich, A. M. J., Mills, N. L., Walsh, T. S. & Gillies, M. A., 1 Nov 2019, In: European journal of anaesthesiology. 36, 11, p. 884-886 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study

Lone, N. I., Lee, R., Salisbury, L., Donaghy, E., Ramsay, P., Rattray, J. & Walsh, T. S., Nov 2019, In: Thorax. 74, 11, p. 1046-1054

Research output: Contribution to journal › Article › peer-review

Open Access

File

Timothy Walsh

Research output

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