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Dive into the research topics where Toni Mchugh is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Research output
- 8 Article
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PLK1-Mediated Phosphorylation Cascade Activates Mis18 Complex to Ensure Centromere Inheritance
Parashara, P., Medina-Pritchard, B., Alba Abad, M., Sotelo-Parrilla, P., Thamkachy, R., Grundei, D., Zou, J., Spanos, C., Kumar, C. N., Basquin, C., Das, V., Yan, Z., Al-Murtadha, A. A., Kelly, D. A., Mchugh, T., Imhof, A., Rappsilber, J. & Jeyaprakash, A. A., 6 Sept 2024, In: Science. 385, 6713, p. 1098–1104 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation
Pantier, R., Brown, M., Han, S., Paton, K., Meek, S., Montavon, T., Shukeir, N., Mchugh, T., Kelly, D., Hochepied, T., Libert, C., Jenuwein, T., Burdon, T. & Bird, A. P., 8 May 2024, In: Nature Communications. 15, 1, p. 1-14 14 p., 3880.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
Gluszek-Kustusz, A., Craske, B., Legal, T., Mchugh, T. & Welburn, J. P. I., 2 Nov 2023, In: The EMBO journal. 42, 21, 18 p., e113647.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Establishment of centromere identity is dependent on nuclear spatial organization
Wu, W., Mchugh, T., Kelly, D. A., Pidoux, A. L. & Allshire, R. C., 25 Jul 2022, In: Current Biology. 32, 14, p. 3121-3136.e6 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC
Abad, M. A., Gupta, T., Hadders, M. A., Meppelink, A., Wopken, J. P., Blackburn, E., Zou, J., Gireesh, A., Buzuk, L., Kelly, D. A., Mchugh, T., Rappsilber, J., Lens, S. M. A. & Jeyaprakash, A. A., 1 Jul 2022, In: Journal of Cell Biology. 221, 8, 16 p., e202108156.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Projects
- 1 Finished
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Developing dynamic microtubule assays in vitro to analyze the role of kinesin-8 motors in MT depolymerization.
Mchugh, T. (Principal Investigator) & Welburn, J. (Co-investigator)
1/06/17 → 30/06/17
Project: Research