Research output per year
Research output per year
Research output
- 8 Article
Search results
-
2024
PLK1-Mediated Phosphorylation Cascade Activates Mis18 Complex to Ensure Centromere Inheritance
Parashara, P., Medina-Pritchard, B., Alba Abad, M., Sotelo-Parrilla, P., Thamkachy, R., Grundei, D., Zou, J., Spanos, C., Kumar, C. N., Basquin, C., Das, V., Yan, Z., Al-Murtadha, A. A., Kelly, D. A., Mchugh, T., Imhof, A., Rappsilber, J. & Jeyaprakash, A. A., 6 Sept 2024, In: Science. 385, 6713, p. 1098–1104 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation
Pantier, R., Brown, M., Han, S., Paton, K., Meek, S., Montavon, T., Shukeir, N., Mchugh, T., Kelly, D., Hochepied, T., Libert, C., Jenuwein, T., Burdon, T. & Bird, A. P., 8 May 2024, In: Nature Communications. 15, 1, p. 1-14 14 p., 3880.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2023
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
Gluszek-Kustusz, A., Craske, B., Legal, T., Mchugh, T. & Welburn, J. P. I., 2 Nov 2023, In: The EMBO journal. 42, 21, 18 p., e113647.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2022
Establishment of centromere identity is dependent on nuclear spatial organization
Wu, W., Mchugh, T., Kelly, D. A., Pidoux, A. L. & Allshire, R. C., 25 Jul 2022, In: Current Biology. 32, 14, p. 3121-3136.e6 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC
Abad, M. A., Gupta, T., Hadders, M. A., Meppelink, A., Wopken, J. P., Blackburn, E., Zou, J., Gireesh, A., Buzuk, L., Kelly, D. A., Mchugh, T., Rappsilber, J., Lens, S. M. A. & Jeyaprakash, A. A., 1 Jul 2022, In: Journal of Cell Biology. 221, 8, 16 p., e202108156.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Potent microtubule depolymerizing activity of a mitotic Kif18b-MCAK-EB network
Mchugh, T. & Welburn, J. P. I., 31 May 2022, In: Journal of Cell Science. 136, 5, 25 p., jcs260144.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2019
The depolymerase activity of MCAK shows graded response to Aurora B kinase phosphorylation through allosteric regulation
Mchugh, T., Zou, J., Volkov, V., Bertin, A., Rappsilber, J., Dogterom, M. & Welburn, J. P. I., 14 Jan 2019, In: Journal of Cell Science. 132, 4, 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Microtubule end tethering of a processive kinesin-8 motor Kif18b is required for spindle positioning
McHugh, T., Gluszek, A. A. & Welburn, J. P. I., 2 Jul 2018, In: Journal of Cell Biology. 217, 7, p. 2403-2416 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile