11B-HSD1 as a therapeutic target in repair following myocardial infarction

Gray, Gillian (Principal Investigator)
Chapman, Karen (Co-investigator)
Hadoke, Patrick (Co-investigator)
Walker, Brian (Co-investigator)

6 Article

6 results

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2017
11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI
Mylonas, K. J., Turner, N. A., Bageghni, S. A., Kenyon, C. J., White, C. I., McGregor, K., Kimmitt, R. A., Sulston, R., Kelly, V., Walker, B. R., Porter, K. E., Chapman, K. E. & Gray, G. A., 1 Jun 2017, In: Journal of Endocrinology. 233, 3, p. 315-327 13 p.
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Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium
Gray, G., White, C. I., Castellan, R. F. P., McSweeney, S. J. & Chapman, K., 1 Jan 2017, In: Journal of molecular endocrinology. 58, 1, p. R1-R13 13 p.
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2016
Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction
Protti, A., Mongue-Din, H., Mylonas, K. J., Sirker, A., Sag, C. M., Swim, M. M., Maier, L., Sawyer, G., Dong, X., Botnar, R., Salisbury, J., Gray, G. A. & Shah, A. M., 1 Jan 2016, In: Journal of Molecular and Cellular Cardiology. 90, p. 120-128
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Cardiomyocyte and vascular smooth muscle independent 11β-hydroxysteroid dehydrogenase 1 amplifies infarct expansion, hypertrophy and the development of heart failure following myocardial infarction in male mice
White, C. I., Jansen, M. A., McGregor, K., Mylonas, K. J., Richardson, R. V., Thomson, A., Moran, C. M., Seckl, J. R., Walker, B. R., Chapman, K. E. & Gray, G. A., 1 Jan 2016, In: Endocrinology . 157, 1, p. 346–357
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2015
Optical projection tomography permits efficient assessment of infarct volume in the murine heart postmyocardial infarction
Zhao, X., Wu, J., Gray, C. D., McGregor, K., Rossi, A. G., Morrison, H., Jansen, M. & Gray, G. A., 15 Aug 2015, In: American Journal of Physiology - Heart and Circulatory Physiology. 309, 4, p. H702-10
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The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’ phenotype in response to Th2 immunologic challenge
Mylonas, K. J., Jenkins, S. J., Castellan, R. F. P., Ruckerl, D., Mcgregor, K., Phythian-adams, A. T., Hewitson, J. P., Campbell, S. M., Macdonald, A. S., Allen, J. E. & Gray, G. A., Jul 2015, In: Immunobiology. 220, 7, p. 924–933 10 p.
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11B-HSD1 as a therapeutic target in repair following myocardial infarction

Research output

Search results

11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium

Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction

Cardiomyocyte and vascular smooth muscle independent 11β-hydroxysteroid dehydrogenase 1 amplifies infarct expansion, hypertrophy and the development of heart failure following myocardial infarction in male mice

Optical projection tomography permits efficient assessment of infarct volume in the murine heart postmyocardial infarction

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’ phenotype in response to Th2 immunologic challenge