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A Digital Twin via First-Principles Modelling and Data Analytics for Process Optimisation in Pharmaceutical Manufacturing
Gerogiorgis, Dimitrios
(Principal Investigator)
School of Engineering
Overview
Fingerprint
Research output
(5)
Project Details
Status
Finished
Effective start/end date
1/10/20
→
31/01/22
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Lomustine
Chemical Compounds
100%
Cubic Equation of State
Chemical Compounds
83%
Monoclonal antibodies
Engineering & Materials Science
83%
Polydispersity
Engineering & Materials Science
82%
Computational fluid dynamics
Engineering & Materials Science
80%
Flow Reaction
Chemical Compounds
75%
cubic equations
Physics & Astronomy
71%
Deposition rates
Engineering & Materials Science
68%
Research output
Research output per year
2021
2021
2022
5
Article
Research output per year
Research output per year
Dynamic simulation, optimisation AND ECONOMIC ANALYSIS of FED-BATCH vs. perfusion bioreactors for advanced mAb manufacturing
Jones, W.
&
Gerogiorgis, D. I.
,
Sep 2022
,
In:
Computers and Chemical Engineering.
165
,
p. 107855
107855.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Monoclonal antibodies
100%
Bioreactors
77%
Binding sites
44%
Antigens
43%
Cell culture
41%
CFD modelling and simulation of drill cuttings transport efficiency in annular bends: Effect of particle size polydispersity
Epelle, E. I.
,
Obande, W.
,
Okolie, J. A.
,
Wilberforce, T.
&
Gerogiorgis, D. I.
,
6 Nov 2021
, (E-pub ahead of print)
In:
Journal of Petroleum Science and Engineering.
p. 109795
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Polydispersity
100%
Particle size
60%
Computational fluid dynamics
48%
particle size
45%
simulation
28%
Flow synthesis kinetics for lomustine, an anti-cancer active pharmaceutical ingredient
Diab, S.
,
Raiyat, M.
&
Gerogiorgis, D. I.
,
19 Jul 2021
, (E-pub ahead of print)
In:
Reaction Chemistry and Engineering.
p. 1-10
10 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Lomustine
100%
Flow Reaction
75%
Nitrosation
58%
Drug products
58%
Pharmaceutical
39%