A forward genetics approach to define driver mutations in bile duct cancer

Boulter, Luke (Principal Investigator)

School of Population Health Sciences

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2021

Notch-IGF1 signalling in biliary epithelial cells drives their expansion and inhibits hepatocyte differentiation
Minnis-Lyons, S., Ferreira-Gonzalez, S., Aleksieva, N., Man, J., Gadd, V., Williams, M., Guest, R. V., Lu, W.-Y., Dwyer, B., Jamieson, T., NIxon, C., Van Hul, N., Lemaigre, F. P., McCafferty, J., Leclercq, I., Sansom, O. J., Boulter, L. & Forbes, S. J., 22 Jun 2021, In: Science Signaling.
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2020
Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors
Wilson, D. H., Jarman, E. J., Mellin, R. P., Wilson, M. L., Waddell, S., Tsokkou, P., Younger, N. T., Raven, A., Bhalla, S. R., Noll, A. T. R., Olde Damink, S. W., Schaap, F. G., Chen, P., Bates, D. O., Banales, J. M., Dean, C. H., Henderson, D. J., Sansom, O. J., Kendall, T. J. & Boulter, L., 23 Jan 2020, In: Nature Communications. 11, 13 p., 445.
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