A Hundred at Ninety: the common cause Hypothesis of Ageing tested in four waves of the Lothian Birth Cohort 1921

2026

Gardening, healthy aging, and longevity: Longitudinal evidence from 25 years of the Lothian Birth Cohort 1921

Corley, J. (Lead Author), Pattie, A., Harris, S. E., Deary, I. J. & Cox, S. R., Feb 2026, In: Journal of Environmental Psychology. 109, 10 p., 102889.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2024

Gardening and cognitive ageing: Longitudinal findings from the Lothian Birth Cohort of 1921

Corley, J. (Lead Author), Pattie, A., Deary, I. J. & Cox, S. R., Aug 2024, In: Journal of Environmental Psychology. 97, 102361.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2020

DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921

Sibbett, R. A., Altschul, D. M., Marioni, R. E., Deary, I. J., Starr, J. M. & Russ, T. C., 28 Feb 2020, In: BMC Psychiatry. 20, 1, 91.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2019

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Erzurumluoglu, A. M., Liu, M., Jackson, V. E., Barnes, D. R., Datta, G., Melbourne, C. A., Young, R. D., Batini, C., Surendran, P., Jiang, T., Adnan, S. D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A. C., Asselbergs, F. W., Baumbach, C., Bierut, L., Bertelsen, S. & Boehnke, M. & 156 others, Bots, M. L., Brazel, D. M., Chambers, J. C., Chang-claude, J., Chen, C., Corley, J., Chou, Y.-L., David, S. P., De Boer, R. A., De Leeuw, C. A., Dennis, J. G., Dominiczak, A. F., Dunning, A. M., Easton, D. F., Eaton, C., Elliott, P., Evangelou, E., Faul, J. D., Foroud, T., Goate, A., Gong, J., Grabe, H. J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A. R., Harris, S. E., Hattersley, A., Heath, A., Hsu, C., Iacono, W. G., Kanoni, S., Kapoor, M., Kaprio, J., Kardia, S. L., Karpe, F., Kontto, J., Kooner, J. S., Kooperberg, C., Kuulasmaa, K., Laakso, M., Lai, D., Langenberg, C., Le, N., Lettre, G., Loukola, A., Luan, J., Madden, P. A. F., Mangino, M., Marioni, R. E., Marouli, E., Marten, J., Martin, N. G., Mcgue, M., Michailidou, K., Mihailov, E., Moayyeri, A., Moitry, M., Müller-nurasyid, M., Naheed, A., Nauck, M., Neville, M. J., Nielsen, S. F., North, K., Perola, M., Pharoah, P. D. P., Pistis, G., Polderman, T. J., Posthuma, D., Poulter, N., Qaiser, B., Rasheed, A., Reiner, A., Renström, F., Rice, J., Rohde, R., Rolandsson, O., Samani, N. J., Samuel, M., Schlessinger, D., Scholte, S. H., Scott, R. A., Sever, P., Shao, Y., Shrine, N., Smith, J. A., Starr, J. M., Stirrups, K., Stram, D., Stringham, H. M., Tachmazidou, I., Tardif, J.-C., Thompson, D. J., Tindle, H. A., Tragante, V., Trompet, S., Turcot, V., Tyrrell, J., Vaartjes, I., Van Der Leij, A. R., Van Der Meer, P., Varga, T. V., Verweij, N., Völzke, H., Wareham, N. J., Warren, H. R., Weir, D. R., Weiss, S., Wetherill, L., Yaghootkar, H., Yavas, E., Jiang, Y., Chen, F., Zhan, X., Zhang, W., Zhao, W., Zhao, W., Zhou, K., Amouyel, P., Blankenberg, S., Caulfield, M. J., Chowdhury, R., Cucca, F., Deary, I. J., Deloukas, P., Di Angelantonio, E., Ferrario, M., Ferrières, J., Franks, P. W., Frayling, T. M., Frossard, P., Hall, I. P., Hayward, C., Jansson, J.-H., Jukema, J. W., Kee, F., Männistö, S., Metspalu, A., Munroe, P. B., Nordestgaard, B. G., Palmer, C. N. A., Salomaa, V., Sattar, N., Spector, T., Strachan, D. P., Van Der Harst, P., Zeggini, E., Saleheen, D., Butterworth, A. S., Wain, L. V., Abecasis, G. R., Danesh, J., Tobin, M. D., Vrieze, S., Liu, D. J. & Howson, J. M. M., 7 Jan 2019, (E-pub ahead of print) In: Molecular Psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Tracking the epigenetic clock across the human life course: A meta-analysis of longitudinal cohort data

Marioni, R., Suderman, M. J., Chen, B. H., Horvath, S., Bandinelli, S., Morris, T. J., Becker, S., Ferrucci, L., Pedersen, N. L., Relton, C. L., Deary, I. & Hägg, S., Jan 2019, In: The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences. 74, 1, p. 1-5 gly060.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2018

Predicting change in quality of life from age 79 to 90 in the Lothian Birth Cohort 1921

Brett, C. E., Dykiert, D., Starr, J. M. & Deary, I. J., 23 Nov 2018, (E-pub ahead of print) In: Quality of Life Research. 28, 3, p. 737–749

Research output: Contribution to journal › Article › peer-review

Open Access

File

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C.-Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R. & Aschard, H. & 254 others, Bartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F.-C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, J., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Ida Chen, Y.-D., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C.-K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W.-P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., Mckenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J.-M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Study, L. C., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X.-O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A., Levy, D. & Kuivaniemi, H., 18 Jun 2018, In: PLoS ONE. 13, 6, p. e0198166 36 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Qi, T., Wu, Y., Zeng, J., Zhang, F., Xue, A., Jiang, L., Zhu, Z., Kemper, K., Yengo, L., Zheng, Z., Marioni, R. E., Montgomery, G. W., Deary, I. J., Wray, N. R., Visscher, P. M., Mcrae, A. F. & Yang, J., 11 Jun 2018, In: Nature Communications. 9, 1, p. 1-12 2282.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Effects of between-person differences and within-person changes in symptoms of anxiety and depression on older-age cognitive performance

Laukka, E. J., Dykiert, D., Allerhand, M., Starr, J. & Deary, I., Jun 2018, In: Psychological Medicine. 48, 8, p. 1350-1358 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Transitions across cognitive states and death among older adults in relation to education: A multistate survival model using data from six longitudinal studies

Robitaille, A., Van Den Hout, A., Machado, R. J. M., Bennett, D. A., Čukić, I., Deary, I. J., Hofer, S. M., Hoogendijk, E. O., Huisman, M., Johansson, B., Koval, A. V., van der Noordt, M., Piccinin, A. M., Rijnhart, J. J. M., Singh-Manoux, A., Skoog, J., Skoog, I., Starr, J., Vermunt, L. & Clouston, S. & 1 others, Muniz Terrera, G., 1 Feb 2018, (E-pub ahead of print) In: Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 14, 4, p. 462-472 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Meta-analysis of epigenome-wide association studies of cognitive abilities

Marioni, R., Mcrae, A. F., Bressler, J., Colicino, E., Hannon, E., Li, S., prada, D., Smith, J. A., Trevisi, L., Tsai, P.-C., Vojinovic, D., Simino, J., Levy, D., Liu, C., Mendelson, M. M., Satizabal, C. L., Yang, Q., Jhun, M. A., Kardia, S. L. R. & Zhao, W. & 27 others, Bandinelli, S., Ferrucci, L., Hernandez, D., Singleton, A. B., Harris, S., Starr, J., Kiel, D. P., McLean, R. R., Just, A. C., Schwartz, J., Spiro, A., Vokonas, P., Amin, N., Ikram, M. A., Uitterlinden, A. G., van Meurs, J. B. J., Spector, T. D., Steves, C., Baccarelli, A. A., Bell, J. T., van Duijn, C. M., Fornage, M., Hsu, Y.-H., Mill, J., Mosley, T. H., Seshadri, S. & Deary, I., 8 Jan 2018, In: Nature.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2017

Identification, replication and characterization of epigenetic remodelling in the aging genome: A cross population analysis

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R., Deary, I. & Tan, Q., 15 Aug 2017, (E-pub ahead of print) In: Scientific Reports. 7, p. 1-8 8183.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Risk factors for dementia in the ninth decade of life and beyond: A study of the Lothian Birth Cohort 1921

Sibbett, R., Russ, T. C., Deary, I. & Starr, J., 2 Jun 2017, In: BMC Psychiatry. 17, p. 1-10 10 p., 205.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921

Gow, A. J., Pattie, A. & Deary, I. J., Jan 2017, In: The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences. 72, 1, p. 25-37

Research output: Contribution to journal › Article › peer-review

Open Access

File

2016

The epigenetic clock and telomere length are independently associated with chronological age and mortality

Marioni, R., Harris, S., Deary, I., Visscher, P. M., Wray, N. R., Mcrae, A. F., Von Zglinicki, T., Shah, S. & Martin-ruiz, C., 13 Apr 2016, (E-pub ahead of print) In: International Journal of Epidemiology.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Life review in advanced age: qualitative research on the 'start in life' of 90-year-olds in the Lothian Birth Cohort 1921

Lapsley, H., Pattie, A., Starr, J. M. & Deary, I. J., 1 Apr 2016, In: BMC Geriatrics. 16, 1, p. 74

Research output: Contribution to journal › Article › peer-review

Open Access

File

A study of common Mendelian disease carriers across ageing British cohorts: Meta-analyses reveal heterozygosity for alpha 1-antitrypsin deficiency increases respiratory capacity and height

North, T.-L., Ben-Shlomo, Y., Cooper, C., Deary, I. J., Gallacher, J., Kivimaki, M., Kumari, M., Martin, R. M., Pattie, A., Sayer, A. A., Starr, J. M., Wong, A., Kuh, D., Rodriguez, S. & Day, I. N. M., 1 Feb 2016, (E-pub ahead of print) In: Journal of Medical Genetics.

Research output: Contribution to journal › Article › peer-review

Open Access

File

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Generation Scotland, Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C. & Hoffmann, P. & 31 others, Karjalainen, J., Lahti, J., Llewellyn, D. J., Schmidt, C. O., Mather, K. A., Chouraki, V., Sun, Q., Resnick, S. M., Rose, L. M., Oldmeadow, C., Stewart, M., Smith, B. H., Gudnason, V., Yang, Q., Mirza, S. S., Jukema, J. W., deJager, P. L., Harris, T. B., Liewald, D., Amin, N., Gow, A. J., Pattie, A., Starr, J. M., McLachlan, S., Porteous, D. J., Price, J. F., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F. & Deary, I., Feb 2016, In: Molecular Psychiatry. 21, p. 189-197

Research output: Contribution to journal › Article › peer-review

Open Access

File

Polygenic risk for coronary artery disease is associated with cognitive ability in older adults

Generation Scotland, Hagenaars, S. P., Harris, S. E., Clarke, T.-K., Hall, L., Luciano, M., Fernandez-Pujals, A. M., Davies, G., Hayward, C., Starr, J. M., Porteous, D. J., McIntosh, A. M. & Deary, I. J., 28 Jan 2016, In: International Journal of Epidemiology. 45, 2, p. 433-440

Research output: Contribution to journal › Article › peer-review

Open Access

File

Genome-wide autozygosity is associated with lower general cognitive ability

Howrigan, D. P., Simonson, M. A., Davies, G., Harris, S. E., Tenesa, A., Starr, J. M., Liewald, D. C., Deary, I. J., McRae, A., Wright, M. J., Montgomery, G. W., Hansell, N., Martin, N. G., Payton, A., Horan, M., Ollier, W. E., Abdellaoui, A., Boomsma, D. I., DeRosse, P. & Knowles, E. E. M. & 27 others, Glahn, D. C., Djurovic, S., Melle, I., Andreassen, O. A., Christoforou, A., Steen, V. M., Hellard, S. L., Sundet, K., Reinvang, I., Espeseth, T., Lundervold, A. J., Giegling, I., Konte, B., Hartmann, A. M., Rujescu, D., Roussos, P., Giakoumaki, S., Burdick, K. E., Bitsios, P., Donohoe, G., Corley, R. P., Visscher, P. M., Pendleton, N., Malhotra, A. K., Neale, B. M., Lencz, T. & Keller, M. C., 2016, In: Molecular Psychiatry. 21, 6, p. 837-843

Research output: Contribution to journal › Article › peer-review

Open Access

File

2015

Integrative pathway genomics of lung function and airflow obstruction

CHARGE Consortium; SpiroMeta Consortium, Gharib, S. A., Loth, D. W., Soler Artigas, M., Birkland, T. P., Wilk, J. B., Wain, L. V., Brody, J. A., Obeidat, M., Hancock, D. B., Tang, W., Rawal, R., Boezen, H. M., Imboden, M., Huffman, J. E., Lahousse, L., Alves, A. C., Manichaikul, A., Hui, J. & Morrison, A. C. & 30 others, Ramasamy, A., Smith, A. V., Gudnason, V., Surakka, I., Vitart, V., Evans, D. M., Strachan, D. P., Deary, I. J., Hofman, A., Gläser, S., Wilson, J. F., North, K. E., Zhao, J. H., Heckbert, S. R., Jarvis, D. L., Probst-Hensch, N., Schulz, H., Barr, R. G., Jarvelin, M.-R., O'Connor, G. T., Kähönen, M., Cassano, P. A., Hysi, P. G., Dupuis, J., Hayward, C., Psaty, B. M., Hall, I. P., Parks, W. C., Tobin, M. D. & London, S. J., 22 Dec 2015, In: Human Molecular Genetics. 24, 23, p. 6836-48 13 p.

Research output: Contribution to journal › Article › peer-review

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

BIOS-consortium, Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S.-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U. & Ahluwalia, T. S. & 31 others, Bonder, M. J., Chen, P., Dehghan, A., Edwards, T. L., Esko, T., Go, M. J., Harris, S. E., Hartiala, J., Kasela, S., Kasturiratne, A., Khor, C.-C., Kleber, M. E., Li, H., Mok, Z. Y., Nakatochi, M., Sapari, N. S., Saxena, R., Stewart, A. F. R., Stolk, L., Tabara, Y., Teh, A. L., Wu, Y., Wu, J.-Y., Zhang, Y., Aits, I., Da Silva Couto Alves, A., Das, S., Davies, G., Liewald, D. C. M., Starr, J. M. & Deary, I. J., 21 Sept 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.

Research output: Contribution to journal › Article › peer-review

Meta-analysis of genome-wide association studies for extraversion: Findings from the Genetics of Personality Consortium

Generation Scotland, van den Berg, S. M., de Moor, M. H. M., Verweij, K. J. H., Krueger, R. F., Luciano, M., Arias Vasquez, A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., Gordon, S. D., Hansell, N. K., Hart, A. B., Seppälä, I., Huffman, J. E., Konte, B., Lahti, J., Lee, M. & Miller, M. & 31 others, Nutile, T., Tanaka, T., Teumer, A., Viktorin, A., Wedenoja, J., Abdellaoui, A., Abecasis, G. R., Adkins, D. E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T. B., Busonero, F., Campbell, H., Costa, P. T., Smith, G. D., Davies, G., de Wit, H., Ding, J., Engelhardt, B. E., Eriksson, J. G., Fedko, I. O., Liewald, D. C., Polasek, O., Starr, J. M., Zgaga, L., Porteous, D., Hayward, C., Rudan, I., Deary, I. J. & Wilson, J. F., 11 Sept 2015, (E-pub ahead of print) In: Behavior Genetics. 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

Genetics of Personality Consortium, 31 Jul 2015, In: JAMA Psychiatry. 72, 7, p. 642-650 9 p.

Research output: Contribution to journal › Article › peer-review

Directional dominance on stature and cognition in diverse human populations

Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V. & Trompet, S. & 30 others, Guo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Campbell, A., Davies, G., Haley, C., Harris, S. E., Hastie, N. D., Kerr, S. M., Liewald, D. C. M., Navarro, P., Redmond, P., Wild, S., BioBank Japan Project, Morris, A. D., Starr, J. M., Deary, I. J., Pirastu, N., Wilson, J. G., Rudan, I., Porteous, D. J., Hayward, C., Wright, A. F., Campbell, H. & Wilson, J. F., 23 Jul 2015, In: Nature. 523, 7561, p. 459-462 4 p.

Research output: Contribution to journal › Article › peer-review

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations

BIOS Consortium, Shah, S., Bonder, M. J., Marioni, R. E., Zhu, Z., McRae, A. F., Zhernakova, A., Harris, S. E., Liewald, D., Henders, A. K., Mendelson, M. M., Liu, C., Joehanes, R., Liang, L., Levy, D., Martin, N. G., Starr, J. M., Wijmenga, C., Wray, N. R. & Yang, J. & 4 others, Montgomery, G. W., Franke, L., Deary, I. J. & Visscher, P. M., 2 Jul 2015, In: American Journal of Human Genetics.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

Clarke, T.-K., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Thomson, P., Hayward, C., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., 30 Jun 2015, In: Translational Psychiatry. 5, e592.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

Huffman, J. E., de Vries, P., Morrison, A. C., Sabater-Lleal, M., Kacprowski, T., Auer, P. L., Brody, J. A., Chasman, D. I., Chen, M.-H., Guo, X., Lin, L.-A., Marioni, R., muller-nurasyid, M., Yanek, L. R., Pankratz, N., Grove, M. L., de Maat, M. P. M., Cushman, M., Wiggins, K. L. & Qi, L. & 47 others, Sennblad, B., Harris, S., Polašek, O., Riess, H., Rivadeneira, F., Rose, L. M., Goel, A., Taylor, K. D., Teumer, A., Uitterlinden, A. G., Vaidya, D., Yao, J., Tang, W., Levy, D., Waldenberger, M., Becker, D. M., Folsom, A. R., Giulianini, F., Greinacher, A., Hofman, A., Huang, C.-C., Kooperberg, C., Silveira, A., Starr, J. M., Strauch, K., Strawbridge, R. J., Wright, A. F., McKnight, B., Franco, O. H., Zakai, N., Mathias, R. A., Psaty, B. M., Ridker, P. M., Tofler, G. H., Voelker, U., Watkins, H., Fornage, M., Hamsten, A., Deary, I., Boerwinkle, E., Koenig, W., Rotter, J. I., Hayward, C., Dehghan, A., Reiner, A. P., O'Donnell, C. J. & Smith, N. L., 23 Jun 2015, In: Blood.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment

Trampush, J. W., Lencz, T., Knowles, E., Davies, G., Guha, S., Pe'er, I., Liewald, D. C., Starr, J. M., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., Mukherjee, S., DeRosse, P., Lundervold, A., Steen, V. M., John, M., Espeseth, T. & Raikkonen, K. & 33 others, Widen, E., Palotie, A., Eriksson, J. G., Giegling, I., Konte, B., Ikeda, M., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Horan, M., Scult, M., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A., Weinberger, D. R., Pendleton, N., Iwata, N., Darvasi, A., Bitsios, P., Rujescu, D., Lahti, J., Le Hellard, S., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C. & Malhotra, A. K., 10 Jun 2015, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 168, 5, p. 363-373 11 p.

Research output: Contribution to journal › Article › peer-review

Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Debette, S., Ibrahim Verbaas, C. A., Bressler, J., Schuur, M., Smith, A., Bis, J. C., Davies, G., Wolf, C., Gudnason, V., Chibnik, L. B., Yang, Q., deStefano, A. L., de Quervain, D. J. F., Srikanth, V., Lahti, J., Grabe, H. J., Smith, J. A., Priebe, L. & Yu, L. & 31 others, Karbalai, N., Hayward, C., Wilson, J. F., Campbell, H., Petrovic, K., Fornage, M., Chauhan, G., Yeo, R., Boxall, R., Becker, J., Stegle, O., Mather, K. A., Chouraki, V., Sun, Q., Rose, L. M., Resnick, S., Oldmeadow, C., Kirin, M., Wright, A. F., Jonsdottir, M. K., Vitart, V., Hastie, N. D., Zgaga, L., Rudan, I., Polasek, O., Liewald, D. C., Gow, A. J., Pattie, A., Starr, J. M., Porteous, D. & Deary, I. J., 15 Apr 2015, In: Biological Psychiatry. 77, 8, p. 749-763 15 p.

Research output: Contribution to journal › Article › peer-review

Genetic basis of a cognitive complexity metric

Hansell, N. K., Halford, G. S., Andrews, G., Shum, D. H. K., Harris, S. E., Davies, G., Franic, S., Christoforou, A., Zietsch, B., Painter, J., Medland, S. E., Ehli, E. A., Davies, G. E., Steen, V. M., Lundervold, A. J., Reinvang, I., Montgomery, G. W., Espeseth, T., Hulshoff Pol, H. E. & Starr, J. M. & 5 others, Martin, N. G., Le Hellard, S., Boomsma, D. I., Deary, I. J. & Wright, M. J., 10 Apr 2015, In: PLoS ONE. 10, 4, p. e0123886

Research output: Contribution to journal › Article › peer-review

Open Access

File

Disentangling wording and substantive factors in the spiritual well-being scale

Murray, A. L., Johnson, W., Gow, A. J. & Deary, I. J., Apr 2015, In: Psychology of Religion and Spirituality. 7, 2, p. 120-129 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

Clarke, T.-K., Lupton, M. K., Fernandez-Pujals, A. M., Starr, J., Davies, G., Cox, S., Pattie, A., Liewald, D. C., Hall, L. S., MacIntyre, D. J., Smith, B. H., Hocking, L. J., Padmanabhan, S., Thomson, P. A., Hayward, C., Hansell, N. K., Montgomery, G. W., Medland, S. E., Martin, N. G. & Wright, M. J. & 3 others, Porteous, D. J., Deary, I. J. & McIntosh, A. M., 10 Mar 2015, In: Molecular Psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V., Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., van der Lee, S. J., Le Hellard, S., Liu, T., Marioni, R. E., Oldmeadow, C., Postmus, I., Smith, A. V., Smith, J. A., Thalamuthu, A. & Thomson, R. & 109 others, Vitart, V., Wang, J., Yu, L., Zgaga, L., Zhao, W., Boxall, R., Harris, S. E., Hill, W. D., Liewald, D. C., Luciano, M., Adams, H., Ames, D., Amin, N., Amouyel, P., Assareh, A. A., Au, R., Becker, J. T., Beiser, A., Berr, C., Bertram, L., Boerwinkle, E., Buckley, B. M., Campbell, H., Corley, J., De Jager, P. L., Dufouil, C., Eriksson, J. G., Espeseth, T., Faul, J. D., Ford, I., Generation Scotland, Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Heiss, G., Hofman, A., Holliday, E. G., Huffman, J., Kardia, S. L. R., Kochan, N., Knopman, D. S., Kwok, J. B., Lambert, J.-C., Lee, T., Li, G., Li, S.-C., Loitfelder, M., Lopez, O. L., Lundervold, A. J., Lundqvist, A., Mather, K. A., Mirza, S. S., Nyberg, L., Oostra, B. A., Palotie, A., Papenberg, G., Pattie, A., Petrovic, K., Polasek, O., Psaty, B. M., Redmond, P., Reppermund, S., Rotter, J. I., Schmidt, H., Schuur, M., Schofield, P. W., Scott, R. J., Steen, V. M., Stott, D. J., van Swieten, J. C., Taylor, K. D., Trollor, J., Trompet, S., Uitterlinden, A. G., Weinstein, G., Widen, E., Windham, B. G., Jukema, J. W., Wright, A. F., Wright, M. J., Yang, Q., Amieva, H., Attia, J. R., Bennett, D. A., Brodaty, H., de Craen, A. J. M., Hayward, C., Ikram, M. A., Lindenberger, U., Nilsson, L.-S., Porteous, D. J., Räikkönen, K., Reinvang, I., Rudan, I., Sachdev, P. S., Schmidt, R., Schofield, P. R., Srikanth, V., Starr, J. M., Turner, S. T., Weir, D. R., Wilson, J. F., Duijn, C. V., Launer, L., Fitzpatrick, A. L., Seshadri, S., Mosley Jr, T. H. & Deary, I. J., 28 Feb 2015, In: Molecular Psychiatry. 20, 2, p. 183-192 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

DNA methylation age of blood predicts all-cause mortality in later life

Marioni, R. E., Shah, S., McRae, A. F., Chen, B. H., Colicino, E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Feinberg, A. P., Fallin, M. D., Multhaup, M. L., Jaffe, A. E. & Joehanes, R. & 11 others, Schwartz, J., Just, A. C., Lunetta, K. L., Murabito, J. M., Starr, J. M., Horvath, S., Baccarelli, A. A., Levy, D., Visscher, P. M., Wray, N. R. & Deary, I. J., 30 Jan 2015, In: Genome Biology. 16, 12 p., 25.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Cognitive consequences of overweight and obesity in the ninth decade of life?

Dahl Aslan, A. K., Starr, J. M., Pattie, A. & Deary, I., 2015, In: Age and Ageing. 44, 1, p. 59-65

Research output: Contribution to journal › Article › peer-review

Open Access

File

2014

Religiosity is negatively associated with later-life intelligence, but not with age-related cognitive decline

Ritchie, S. J., Gow, A. J. & Deary, I. J., 1 Sept 2014, In: Intelligence. 46, p. 9-17

Research output: Contribution to journal › Article › peer-review

Open Access

File

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function

Tang, W., Kowgier, M., Loth, D. W., Soler Artigas, M., Joubert, B. R., Hodge, E., Gharib, S. A., Smith, A. V., Ruczinski, I., Gudnason, V., Mathias, R. A., Harris, T. B., Hansel, N. N., Launer, L. J., Barnes, K. C., Hansen, J. G., Albrecht, E., Aldrich, M. C., Allerhand, M. & Barr, R. G. & 59 others, Brusselle, G. G., Couper, D. J., Curjuric, I., Davies, G., Deary, I. J., Dupuis, J., Fall, T., Foy, M., Franceschini, N., Gao, W., Gläser, S., Gu, X., Hancock, D. B., Heinrich, J., Hofman, A., Imboden, M., Ingelsson, E., James, A., Karrasch, S., Koch, B., Kritchevsky, S. B., Kumar, A., Lahousse, L., Li, G., Lind, L., Lindgren, C., Liu, Y., Lohman, K., Lumley, T., McArdle, W. L., Meibohm, B., Morris, A. P., Morrison, A. C., Musk, B., North, K. E., Palmer, L. J., Probst-Hensch, N. M., Psaty, B. M., Rivadeneira, F., Rotter, J. I., Schulz, H., Smith, L. J., Sood, A., Starr, J. M., Strachan, D. P., Teumer, A., Uitterlinden, A. G., Völzke, H., Voorman, A., Wain, L. V., Wells, M. T., Wilk, J. B., Williams, O. D., Heckbert, S. R., Stricker, B. H., London, S. J., Fornage, M., Hall, I. P. & Cassano, P. A., 1 Jul 2014, In: PLoS ONE. 9, 7, p. e100776

Research output: Contribution to journal › Article › peer-review

Open Access

File

Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory

van den Berg, S. M., de Moor, M. H. M., McGue, M., Pettersson, E., Terracciano, A., Verweij, K. J. H., Amin, N., Derringer, J., Esko, T., van Grootheest, G., Hansell, N. K., Huffman, J., Konte, B., Lahti, J., Luciano, M., Matteson, L. K., Viktorin, A., Wouda, J., Agrawal, A. & Allik, J. & 68 others, Bierut, L., Broms, U., Campbell, H., Smith, G. D., Eriksson, J. G., Ferrucci, L., Franke, B., Fox, J.-P., de Geus, E. J. C., Giegling, I., Gow, A. J., Grucza, R., Hartmann, A. M., Heath, A. C., Heikkilä, K., Iacono, W. G., Janzing, J., Jokela, M., Kiemeney, L., Lehtimäki, T., Madden, P. A. F., Magnusson, P. K. E., Northstone, K., Nutile, T., Ouwens, K. G., Palotie, A., Pattie, A., Pesonen, A.-K., Polasek, O., Pulkkinen, L., Pulkki-Råback, L., Raitakari, O. T., Realo, A., Rose, R. J., Ruggiero, D., Seppälä, I., Slutske, W. S., Smyth, D. C., Sorice, R., Starr, J. M., Sutin, A. R., Tanaka, T., Verhagen, J., Vermeulen, S., Vuoksimaa, E., Widen, E., Willemsen, G., Wright, M. J., Zgaga, L., Rujescu, D., Metspalu, A., Wilson, J. F., Ciullo, M., Hayward, C., Rudan, I., Deary, I. J., Räikkönen, K., Arias Vasquez, A., Costa, P. T., Keltikangas-Järvinen, L., van Duijn, C. M., Penninx, B. W. J. H., Krueger, R. F., Evans, D. M., Kaprio, J., Pedersen, N. L., Martin, N. G. & Boomsma, D. I., Jul 2014, In: Behavior Genetics. 44, 4, p. 295-313 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

GWAS-based pathway analysis differentiates between fluid and crystallized intelligence

Christoforou, A., Espeseth, T., Davies, G., Fernandes, C. P. D., Giddaluru, S., Mattheisen, M., Tenesa, A., Harris, S. E., Liewald, D. C., Payton, A., Ollier, W., Horan, M., Pendleton, N., Haggarty, P., Djurovic, S., Herms, S., Hoffman, P., Cichon, S., Starr, J. M. & Lundervold, A. & 4 others, Reinvang, I., Steen, V. M., Deary, I. J. & Le Hellard, S., 28 Jun 2014, In: Genes, Brain and Behavior. 13, 7, p. 663-674

Research output: Contribution to journal › Article › peer-review

Open Access

File

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936

Lyall, D. M., Harris, S. E., Bastin, M. E., Munoz-Maniega, S., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Hernandez, M. D. C. V., Royle, N. A., Starr, J. M., Porteous, D. J., Wardlaw, J. M. & Deary, I. J., Jun 2014, In: Neurobiology of Aging. 35, 6, p. 1513.e25–1513.e33 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Predicting cognitive ability in ageing cohorts using Type 2 diabetes genetic risk

Luciano, M., Mõttus, R., Harris, S. E., Davies, G., Payton, A., Ollier, W. E. R., Horan, M. A., Starr, J. M., Porteous, D. J., Pendleton, N. & Deary, I. J., Jun 2014, In: Diabetic Medicine. 31, 6, p. 714-720 7 p.

Research output: Contribution to journal › Article › peer-review

Childhood cognitive ability accounts for associations between cognitive ability and brain cortical thickness in old age

Karama, S., Bastin, M. E., Murray, C., Royle, N. A., Penke, L., Munoz-Maniega, S., Gow, A. J., Corley, J., Valdés Hernández, M., Lewis, J. D., Rousseau, M.-E., Lepage, C., Fonov, V., Collins, D. L., Booth, T., Rioux, P., Sherif, T., Adalat, R., Starr, J. M. & Evans, A. C. & 2 others, Wardlaw, J. M. & Deary, I. J., May 2014, In: Molecular Psychiatry. 19, 5, p. 555-559 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability

Marioni, R. E., Penke, L., Davies, G., Huffman, J. E., Hayward, C. & Deary, I. J., 22 Apr 2014, In: Proceedings of the Royal Society B-Biological Sciences. 281, 1781, 7 p., 20140117.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Lower Ankle-Brachial Index Is Related to Worse Cognitive Performance in Old Age

Laukka, E. J., Starr, J. M. & Deary, I. J., Mar 2014, In: Neuropsychology. 28, 2, p. 281-289 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

NHLBI GO Exome Sequencing Project, Peloso, G. M., Auer, P. L., Bis, J. C., Voorman, A., Morrison, A. C., Stitziel, N. O., Brody, J. A., Khetarpal, S. A., Crosby, J. R., Fomage, M., Isaacs, A., Jakobsdottir, J., Feitosa, M. F., Davies, G., Huffman, J. E., Manichaikul, A., Davis, B., Lohman, K. & Joon, A. Y. & 31 others, Smith, A. V., Grove, M. L., Zanoni, P., Redon, V., Demissie, S., Lawson, K., Peters, U., Carlson, C., Jackson, R. D., Ryckman, K. K., Mackey, R. H., Robinson, J. G., Siscovick, D. S., Schreiner, P. J., Mychaleckyj, J. C., Pankow, J. S., Holman, A., Uitterlinden, A. G., Harris, T. B., Taylor, K. D., Stafford, J. M., Reynolds, L. M., Marioni, R. E., Dehghan, A., Franco, O. H., Patele, A. P., Starr, J. M., Rudan, I., Hayward, C., Polasek, O. & Deary, I. J., 6 Feb 2014, In: American Journal of Human Genetics. 94, 2, p. 223-232 10 p.

Research output: Contribution to journal › Article › peer-review

Childhood intelligence is heritable, highly polygenic and associated with FNBP1L

Wellcome Trust Case Control Consortium 2 (WTCCC2), Benyamin, B., Pourcain, B., Davis, O. S., Davies, G., Hansell, N. K., Brion, M.-J., Kirkpatrick, R. M., Cents, R. A. M., Franić, S., Miller, M. B., Haworth, C. M. A., Meaburn, E., Price, T. S., Evans, D. M., Timpson, N., Kemp, J., Ring, S., McArdle, W. & Medland, S. E. & 24 others, Yang, J., Harris, S. E., Liewald, D. C., Scheet, P., Xiao, X., Hudziak, J. J., de Geus, E. J. C., Jaddoe, V. W. V., Starr, J. M., Verhulst, F. C., Pennell, C., Tiemeier, H., Iacono, W. G., Palmer, L. J., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Posthuma, D., McGue, M., Wright, M. J., Davey Smith, G., Deary, I. J., Plomin, R. & Visscher, P. M., Feb 2014, In: Molecular Psychiatry. 19, 2, p. 253-8 6 p.

Research output: Contribution to journal › Article › peer-review

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)

Lencz, T., Knowles, E., Davies, G., Guha, S., Liewald, D. C., Starr, J. M., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., Mukherjee, S., Derosse, P., Lundervold, A., Steen, V. M., John, M., Espeseth, T., Räikkönen, K., Widen, E. & Palotie, A. & 26 others, Eriksson, J. G., Giegling, I., Konte, B., Ikeda, M., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Horan, M., Donohoe, G., Morris, D., Corvin, A., Gill, M., Pendleton, N., Iwata, N., Darvasi, A., Bitsios, P., Rujescu, D., Lahti, J., Hellard, S. L., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C. & Malhotra, A. K., Feb 2014, In: Molecular Psychiatry. 19, 2, p. 168-174 7 p.

Research output: Contribution to journal › Article › peer-review

Circulating Inflammatory Markers Are Associated With Magnetic Resonance Imaging-Visible Perivascular Spaces But Not Directly With White Matter Hyperintensities

Aribisala, B. S., Wiseman, S., Morris, Z., Valdes Hernandez, M., Royle, N. A., Munoz-Maniega, S., Gow, A. J., Corley, J., Bastin, M. E., Starr, J., Deary, I. J. & Wardlaw, J. M., 7 Jan 2014, In: Stroke. 45, 2, p. 605-607 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

Hill, W. D., Davies, G., Van De Lagemaat, L. N., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S. & Espeseth, T. & 7 others, Lundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C. & Deary, I. J., 7 Jan 2014, In: Translational Psychiatry. 4, 1, 8 p., 341.

Research output: Contribution to journal › Article › peer-review

Open Access

File

A Hundred at Ninety: the common cause Hypothesis of Ageing tested in four waves of the Lothian Birth Cohort 1921

Research output

Search results

2026

2024

2020

2019

2018

2017

2016

2015

2014