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A Research Consortium to Define the Function of MeCP2: A Step Towards the Development of Therapeutics for Treating Rett Syndrome
Bird, Adrian
(Principal Investigator)
School of Biological Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Active
Effective start/end date
15/01/17
→
31/12/25
Funding
Non-EU industry, commerce and public corporations:
£751,119.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Nuclear Localization Signals
Medicine & Life Sciences
100%
DNA
Medicine & Life Sciences
71%
Chromatin Immunoprecipitation Sequencing
Medicine & Life Sciences
66%
Mutation
Chemical Compounds
65%
Rett Syndrome
Medicine & Life Sciences
52%
Nuclear Proteins
Medicine & Life Sciences
46%
Epigenomics
Medicine & Life Sciences
45%
Methyl-CpG-Binding Protein 2
Medicine & Life Sciences
39%
Research output
Research output per year
2018
2018
2020
2020
2
Article
Research output per year
Research output per year
Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo
Connelly, J. C.
,
Cholewa-waclaw, J.
,
Webb, S.
,
Steccanella, V.
,
Waclaw, B.
&
Bird, A.
,
17 Feb 2020
,
In:
Nucleic Acids Research.
gkaa102.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Chromatin Immunoprecipitation Sequencing
100%
Epigenomics
67%
Methyl-CpG-Binding Protein 2
58%
Thymine
52%
In Vitro Techniques
50%
Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2
Lyst, M. J.
,
Ekiert, R.
,
Guy, J.
,
Selfridge, J.
,
Koerner, M. V.
,
Merusi, C.
,
De Sousa, D.
&
Bird, A.
,
28 Aug 2018
,
In:
Cell Reports.
24
,
9
,
p. 2213-2220
8 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Nuclear Localization Signals
100%
Mutation
65%
Rett Syndrome
52%
DNA
43%
Disorder
33%