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Adipose glucocorticoid exposure is regulated by proteolytic cleavage of CBG
Nixon, Mark
(Principal Investigator)
Deanery of Clinical Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/10/18
→
6/01/24
Funding
British Heart Foundation:
£678,429.00
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Adipose Tissue
Immunology and Microbiology
100%
Neutrophil
Immunology and Microbiology
100%
Corticosteroid-Binding Globulin
Immunology and Microbiology
100%
Glucocorticoid
Immunology and Microbiology
100%
Alpha 1-Antitrypsin
Immunology and Microbiology
100%
Perivascular Adipose Tissue
Medicine and Dentistry
100%
Cardiovascular Disease
Pharmacology, Toxicology and Pharmaceutical Science
100%
Patient History of Bilateral Ovariectomy
Pharmacology, Toxicology and Pharmaceutical Science
50%
Research output
Research output per year
2025
2025
2025
2
Article
Research output per year
Research output per year
Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones: Short title: Obesity induces sex-specific responses in mesenteric PVAT
Ivatt, L.,
Paul, M.
, Miguelez-Crespo, A.,
Hadoke, P. W. F.
,
Bailey, M. A.
, Morgan, R. A. &
Nixon, M.
,
24 Jan 2025
,
In:
Cardiovascular diabetology.
24
,
1
, 39.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Perivascular Adipose Tissue
100%
Cardiovascular Disease
100%
RNA-Sequencing
50%
Cardiovascular Risk
50%
Vascular Disease
50%
The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure
Boyle, L. D., Miguelez-Crespo, A.,
Paul, M.
, Villalobos, E., Toews, J. N. C., Ivatt, L., Nagy, B., Magennis, M.,
Homer, N. Z. M.
,
Andrew, R.
, Viau, V., Hammond, G. L.,
Stimson, R. H.
, Walker, B. R. &
Nixon, M.
,
9 Jan 2025
,
In:
Nature Communications.
16
, 545.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Neutrophil
100%
Adipose Tissue
100%
Glucocorticoid
100%
Alpha 1-Antitrypsin
100%
Corticosteroid-Binding Globulin
100%