Carbon monoxide and metal carbonyl CO-releasing molecules (CORMs) as novel antimicrobial agents - a systems approach to cellular targets and effects.

Sanguinetti, Guido (Principal Investigator)

School of Informatics

Status	Finished
Effective start/end date	15/10/10 → 30/06/14

Funding

Biotechnology and Biological Sciences Research Council: £338,380.00

Carbon monoxide gas is not inert, but global, in its consequences for bacterial gene expression, iron acquisition and antibiotic resistance
Wareham, L. K., Begg, R., Jesse, H. E., Van Beilen, J., Ali, S., Svistunenko, D., McLean, S., Hellingwerf, K., Sanguinetti, G. & Poole, R. K., 13 Jun 2016, In: Antioxidants and Redox Signaling. 24, 17, p. 1013-1028 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Analysis of transcript changes in a heme-deficient mutant of Escherichia coli in response to CORM-3 [Ru(CO)3Cl(glycinate)]
Wilson, J. L., Mclean, S., Begg, R., Sanguinetti, G. & Poole, R. K., 1 Sept 2015, In: Genomics Data. 5, p. 231-234 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO) 3 Cl (glycinate)] Actions on a Heme-Deficient Mutant of Escherichia coli
Wilson, J. L., Wareham, L. K., Mclean, S., Begg, R., Greaves, S., Mann, B. E., Sanguinetti, G. & Poole, R. K., 25 Jun 2015, In: Antioxidants and Redox Signaling. 23, 2, p. 148-162 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File