Research output per year
Research output per year
- 30 results
Search results
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2024
Nasal cathelicidin is expressed in early life and is increased during mild, but not severe Respiratory Syncytial Virus infection
Sintoris, S., Binkowska, J., Gillan, J., Zuurbier, R. P., Twynam-Perkins, J., Kristensen, M., Melrose, L., Lusarreta Parga, P., Ruiz-Rodriguez, A., Chu, M. L., Van Boeckel, S., Wildenbeest, J. G., Bowdish, D. M. E., Currie, A. J., Thwaites, R. S., Schwarze, J., van Houten, M. A., Boardman, J. P., Cunningham, S., Bogaert, D., & 1 others, 17 Jun 2024, In: Scientific Reports. 14, 1, 13928.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro
Shelley, J. R., Mchugh, B. J., Wills, J., Dorin, J. R., Weller, R., Clarke, D. J. & Davidson, D. J., 8 Feb 2023, In: Scientific Reports. 13, 1, 2271.Research output: Contribution to journal › Article › peer-review
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2021
Dysregulation of Prostaglandins, Leukotrienes and Lipoxin A4 in Bronchiectasis
Bedi, P., Zeigler, K., Whitfield, P. D., Davidson, D. J., Rossi, A. G. & Hill, A., 17 Nov 2021, (E-pub ahead of print) In: Thorax.Research output: Contribution to journal › Article › peer-review
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Macrophages from gut-corrected CF mice express human CFTR and lack a pro-inflammatory phenotype
Gillan, J., Hardisty, G., Davidson, D. J. & Gray, R. D., 16 Nov 2021, In: Journal of Cystic Fibrosis.Research output: Contribution to journal › Article › peer-review
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High purity isolation of low density neutrophils casts doubt on their exceptionality in health and disease
Hardisty, G., Llanwarne, F., Minns, D., Gillan, J., Davidson, D. J., Gwyer Findlay, E. L. & Gray, R. D., 8 Jun 2021, In: Frontiers in Immunology. 12, 625922.Research output: Contribution to journal › Article › peer-review
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The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
Minns, D., Smith, K. J., Alessandrini, V., Hardisty, G., Melrose, L., Jackson-Jones, L., MacDonald, A. S., Davidson, D. J. & Gwyer Findlay, E. L., 24 Feb 2021, In: Nature Communications.Research output: Contribution to journal › Article › peer-review
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2020
Inflammation-mediated generation and inflammatory potential of human placental cell-free fetal DNA
Van Boeckel, S. R., Macpherson, H., Norman, J. E., Davidson, D. J. & Stock, S. J., 1 Apr 2020, In: Placenta. 93, p. 49-55Research output: Contribution to journal › Article › peer-review
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2019
Cathelicidins and the onset of labour
van Boeckel, S. R., Hrabalkova, L., Baker, T. L., MacPherson, H., Frew, L., Boyle, A. K., McHugh, B. J., Wilson, K., Norman, J. E., Dorin, J. R., Davidson, D. J. & Stock, S. J., 14 May 2019, In: Scientific Reports. 9, 12 p., 7356.Research output: Contribution to journal › Article › peer-review
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Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy
Findlay, E. G., Currie, A. J., Zhang, A., Ovciarikova, J., Young, L., Stevens, H., McHugh, B. J., Canel, M., Gray, M., Milling, S. W. F., Campbell, J. D. M., Savill, J., Serrels, A. & Davidson, D. J., 1 May 2019, (E-pub ahead of print) In: OncoImmunology. p. 1-17Research output: Contribution to journal › Article › peer-review
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Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa
McHugh, B. J., Wang, R., Li, H-N., Beaumont, P. E., Kells, R., Stevens, H., Young, L., Rossi, A. G., Gray, R. D., Dorin, J. R., Gwyer Findlay, E. L., Brough, D. & Davidson, D. J., 12 Apr 2019, In: PLoS Pathogens. 15, 4, e1007694.Research output: Contribution to journal › Article › peer-review
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2018
Blood Neutrophils are Reprogrammed in Bronchiectasis
Bedi, P., Davidson, D. J., McHugh, B. J., Rossi, A. G. & Hill, A. T., 1 Oct 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 7, p. 880-890Research output: Contribution to journal › Article › peer-review
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Microbial Host Interactions and Impaired Wound Healing in Mice and Humans: Defining a Role for BD14 and NOD2
Williams, H., Campbell, L., Crompton, R. A., Singh, G., McHugh, B. J., Davidson, D. J., McBain, A. J., Cruikshank, S. M. & Hardman, M. J., 1 Oct 2018, In: Journal of Investigative Dermatology. 138, 10, p. 2264-2274Research output: Contribution to journal › Article › peer-review
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Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis
Gray, R. D., Hardisty, G., Regan, K. H., Smith, M., Robb, C. T., Duffin, R., Mackellar, A., Felton, J. M., Paemka, L., McCullagh, B. N., Lucas, C. D., David, D., McKone, E. F., Cooke, G., Donnelly, S. C., Singh, P. K., Stoltz, D. A., Haslett, C., McCray, P. B., Whyte, M. K. B., & 2 others, Feb 2018, In: Thorax. 73, 2, p. 134-144 11 p.Research output: Contribution to journal › Article › peer-review
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2017
Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota
McFarlane, A. J., McSorley, H. J., Davidson, D. J., Fitch, P. M., Errington, C., Mackenzie, K. J., Gollwitzer, E. S., Johnston, C. J. C., MacDonald, A. S., Edwards, M. R., Harris, N. L., Marsland, B. J., Maizels, R. M. & Schwarze, J., 1 Oct 2017, In: Journal of Allergy and Clinical Immunology. 140, 4, p. 1068-1078.e6Research output: Contribution to journal › Article › peer-review
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Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction
Thevaranjan, N., Puchta, A., Schulz, C., Naidoo, A., Szamosi, J. C., Verschoor, C. P., Loukov, D., Schenck, L. P., Jury, J., Foley, K. P., Schertzer, J. D., Larché, M. J., Davidson, D. J., Verdú, E. F., Surette, M. G. & Bowdish, D. M. E., 12 Apr 2017, In: Cell Host & Microbe. 21, 4, p. 455-466.E4 16 p.Research output: Contribution to journal › Article › peer-review
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Human β-defensin 3 increases the TLR9-dependent response to bacterial DNA
Mcglasson, S. L., Semple, F., Macpherson, H., Gray, M., Davidson, D. J. & Dorin, J. R., 7 Apr 2017, In: European Journal of Immunology. 47, 4Research output: Contribution to journal › Article › peer-review
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IL-1beta-induced protection of keratinocytes against Staphylococcus aureus-secreted proteases is mediated by human beta defensin 2
Wang, B., McHugh, B. J., Qureshi, A., Campopiano, D. J., Clarke, D. J., Fitzgerald, J. R., Dorin, J. R., Weller, R. & Davidson, D. J., Jan 2017, In: Journal of Investigative Dermatology. 137, 1, p. 95-105Research output: Contribution to journal › Article › peer-review
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2016
Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans.
Currie, S. M., Gwyer Findlay, E., McFarlane, A., Fitch, P., Boettcher, A., Colegrave, N., Paras, A., Jozwik, A., Chiu, C., Schwarze, J. & Davidson, D. J., 12 Feb 2016, (E-pub ahead of print) In: The Journal of Immunology. 196, 6, p. 2699-2710 11 p.Research output: Contribution to journal › Article › peer-review
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2015
Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid
Semple, F., MacPherson, H., Webb, S., Kilanowski, F., Lettice, L., McGlasson, S. L., Wheeler, A. P., Chen, V., Millhauser, G. L., Melrose, L., Davidson, D. J. & Dorin, J. R., 8 Dec 2015, In: PLoS Genetics. 11, 12, e1005673.Research output: Contribution to journal › Article › peer-review
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Antimicrobial protein and Peptide concentrations and activity in human breast milk consumed by preterm infants at risk of late-onset neonatal sepsis
Trend, S., Strunk, T., Hibbert, J., Kok, C. H., Zhang, G., Doherty, D. A., Richmond, P., Burgner, D., Simmer, K., Davidson, D. J. & Currie, A. J., 2 Feb 2015, In: PLoS ONE. 10, 2, e0117038.Research output: Contribution to journal › Article › peer-review
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2014
Differential response to bacteria, and TOLLIP expression, in the human respiratory tract
Moncayo-nieto, O. L., Wilkinson, T. S., Brittan, M., Mchugh, B. J., Jones, R. O., Conway Morris, A., Walker, W. S., Davidson, D. J. & Simpson, A. J., 11 Sept 2014, In: BMJ Open Respiratory Research. 1, 1, p. e000046-e000046Research output: Contribution to journal › Article › peer-review
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Human cathelicidin production by the cervix
Frew, L., Makieva, S., McKinlay, A. T. M., McHugh, B. J., Doust, A., Norman, J. E., Davidson, D. J. & Stock, S. J., 4 Aug 2014, In: PLoS ONE. 9, 8, e103434.Research output: Contribution to journal › Article › peer-review
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Cathelicidin Host Defence Peptide Augments Clearance of Pulmonary Pseudomonas aeruginosa Infection by Its Influence on Neutrophil Function In Vivo
Beaumont, P. E., McHugh, B., Gwyer Findlay, E., Mackellar, A., Mackenzie, K. J., Gallo, R. L., Govan, J. R. W., Simpson, A. J. & Davidson, D. J., 2 Jun 2014, In: PLoS ONE. 9, 6, e99029.Research output: Contribution to journal › Article › peer-review
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Atorvastatin as a stable treatment in bronchiectasis: a randomised controlled trial
Mandal, P., Chalmers, J. D., Graham, C., Harley, C., Sidhu, M. K., Doherty, C., Govan, J. W., Sethi, T., Davidson, D. J., Rossi, A. G. & Hill, A. T., 1 Jun 2014, In: The Lancet Respiratory Medicine. 2, 6, p. 455-463 9 p.Research output: Contribution to journal › Article › peer-review
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RNA:DNA hybrids are a novel molecular pattern sensed by TLR9
Rigby, R. E., Webb, L. M., Mackenzie, K. J., Li, Y., Leitch, A., Reijns, M. A. M., Lundie, R. J., Revuelta, A., Davidson, D. J., Diebold, S., Modis, Y., MacDonald, A. S. & Jackson, A. P., 18 Mar 2014, In: EMBO Journal. 33, 6, p. 542-558 17 p.Research output: Contribution to journal › Article › peer-review
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2013
Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients
Morris, A. C., Anderson, N., Brittan, M., Wilkinson, T. S., McAuley, D. F., Antonelli, J., McCulloch, C., Barr, L. C., Dhaliwal, K., Jones, R. O., Haslett, C., Hay, A. W., Swann, D. G., Laurenson, I. F., Davidson, D. J., Rossi, A. G., Walsh, T. S. & Simpson, A. J., Nov 2013, In: British Journal of Anaesthesia. 111, 5, p. 778-787 10 p.Research output: Contribution to journal › Article › peer-review
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The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
Currie, S. M., Gwyer Findlay, E., McHugh, B. J., Mackellar, A., Man, T., Macmillan, D., Wang, H., Fitch, P. M., Schwarze, J. & Davidson, D. J., 30 Aug 2013, In: PLoS ONE. 8, 8, 10 p., e73659.Research output: Contribution to journal › Article › peer-review
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A Randomized Controlled Trial of Peripheral Blood Mononuclear Cell Depletion in Experimental Human Lung Inflammation
Barr, L. C., Brittan, M., Conway Morris, A., McAuley, D. F., McCormack, C., Fletcher, A. M., Richardson, H., Connell, M., Patel, D., Wallace, W., Rossi, A. G., Davidson, D. J., Manson, L., Turner, M., Hirani, N., Walsh, T. S., Anderson, N. H., Dhaliwal, K. & Simpson, A. J., Aug 2013, In: American Journal of Respiratory and Critical Care Medicine. 188, 4, p. 449-455Research output: Contribution to journal › Article › peer-review
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Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps
Gray, R. D., Lucas, C., Mackellar, A., Li, F., Hiersemenzel, K., Haslett, C., Davidson, D. J. & Rossi, A. G., 21 Mar 2013, In: Journal of inflammation. 10, 1, 8 p., 12.Research output: Contribution to journal › Article › peer-review
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2011
Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
Barlow, P. G., Svoboda, P., Mackellar, A., Nash, A. A., York, I. A., Pohl, J., Davidson, D. J. & Donis, R. O., 21 Oct 2011, In: PLoS ONE. 6, 10, 9 p., e25333.Research output: Contribution to journal › Article › peer-review
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