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Cell-Specific PRC1 Accessory Proteins and the Regulation of Mammalian Neurodevelopment
Illingworth, Robert
(Principal Investigator)
Deanery of Clinical Sciences
Overview
Fingerprint
Research output
(3)
Project Details
Status
Active
Effective start/end date
1/04/19
→
31/03/24
Funding
MRC:
£1,504,549.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Polycomb Repressive Complex 1
Medicine & Life Sciences
100%
Melanocytes
Medicine & Life Sciences
66%
Chromatin
Medicine & Life Sciences
61%
Phosphoric Monoester Hydrolases
Medicine & Life Sciences
59%
Cell Differentiation
Medicine & Life Sciences
47%
Genes
Medicine & Life Sciences
47%
Stem Cells
Medicine & Life Sciences
42%
Embryonic Development
Medicine & Life Sciences
35%
Research output
Research output per year
2019
2019
2020
2020
3
Article
Research output per year
Research output per year
PRL3-DDX21 transcriptional control of endolysosomal genes restricts melanocyte stem cell differentiation
Johansson, J.
,
Marie, K. L.
,
Lu, Y.
,
Brombin, A.
,
Santoriello, C.
,
Zeng, Z.
,
Zich, J.
,
Gautier, P.
,
von Kriegsheim, A.
,
Brunsdon, H.
,
Wheeler, A. P.
,
Dreger, M.
,
Houston, D. R.
,
Dooley, C. M.
,
Sims, A. H.
,
Busch-Nentwich, E. M.
,
Zon, L. I.
,
Illingworth, R.
&
Patton, E. E.
,
10 Aug 2020
,
In:
Developmental Cell.
54
,
3
,
p. 317-332.E9
16 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Melanocytes
100%
Phosphoric Monoester Hydrolases
89%
Cell Differentiation
71%
Stem Cells
65%
Liver
45%
A Central Role for Canonical PRC1 in Shaping the 3D Nuclear Landscape
Boyle, S.
,
Flyamer, I. M.
,
Williamson, I.
,
Sengupta, D.
,
Bickmore, W.
&
Illingworth, R.
,
1 Jul 2020
,
In:
Genes & Development.
34
,
13-14
,
p. 931-949
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Polycomb Repressive Complex 1
100%
Polycomb-Group Proteins
17%
Mouse Embryonic Stem Cells
14%
Gene Silencing
12%
Transcriptional Activation
10%
Chromatin Folding and Nuclear Architecture: PRC1 Function in 3D
Illingworth, R.
,
16 Jul 2019
,
In:
Current Opinion in Genetics and Development.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Chromatin
100%
Embryonic Development
69%
Genes
45%
Genome
25%
Gene Expression
22%