CHRNI Cleft: Determining the global research priorities for orofacial clefts

Project Details


Orofacial clefts are complex conditions with numerous management options. On a global stage, the management of cleft varies considerably between countries. Reasons include differences in social and genetic risk factors, burdens of disease and overall health spending. A “one size fits all approach” to fixing clefts does not and cannot exist. Thus, research into clefts presents infinite avenues of research interest. Competing research options require relative prioritisation to ensure sustained, measurable improvements.

The aims of this study are twofold:
1. To identify the top global research priorities in OFC research for the next ten years.
2) To provide recommendations to policymakers, funding agencies and other stakeholders for future research investments in cleft palates +/- lip.

Methods and analytical approach:
This study will comprise of a research priority setting exercise using the CHNRI method to address contemporary issues in global OFC research. The CHNRI method provides a transparent framework to conduct a research priority setting exercise. It measures the collective optimism of researchers about a specific area of medicine. The CHRNI method generates a list of research question which are scored by technical experts against specific criteria. These questions are assigned overall “priority scores” on a quantitative scale of 0-100% which provide useful information to funders, policymakers and researchers on the most salient research priorities in a given field.
Effective start/end date21/03/2131/07/21


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.