Research output per year
Research output per year
- 36 results
Search results
-
2023
Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes
Jiang, F., Boakye, D., Sun, J., Wang, L., Yu, L., Zhou, X., Zhao, J., Bian, Z., Song, P., He, Y., Zhu, Y., Chen, J., Yuan, S., Song, M., Larsson, S. C., Giovannucci, E. L., Theodoratou, E., Ding, K. & Li, X., 1 Nov 2023, In: International Journal of Cancer. 153, 9, p. 1602-1611 10 p.Research output: Contribution to journal › Article › peer-review
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Dietary inflammatory indices are not associated with inflammatory bowel disease incidence and progression
Wellens, J., Chen, J., Fu, T., Zhang, Y., Kalla, R., Satsangi, J., Theodoratou, E. & Li, X., 25 Oct 2023, (E-pub ahead of print) In: Inflammatory Bowel Diseases. 6 p., izad249.Research output: Contribution to journal › Article › peer-review
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Exploring the cross-cancer effect of smoking and its fingerprints in blood DNA methylation on multiple cancers: a mendelian randomization study
Zhou, Y., Zhou, X., Sun, J., Wang, L., Zhao, J., Chen, J., Yuan, S., He, Y., Timofeeva, M., Spiliopoulou, A., Mesa-Eguiagaray, I., Farrington, S. M., Ding, K., Dunlop, M. G., Xiao, Q., Theodoratou, E. & Li, X., 15 Oct 2023, In: International Journal of Cancer. 153, 8, p. 1477-1486 10 p.Research output: Contribution to journal › Article › peer-review
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National and subnational incidence, mortality and associated factors of colorectal cancer in China: A systematic analysis and modelling study
Rudan, I., Theodoratou, E., Song, P., Li, X. & Global Health Epidemiology Reference Group (GHERG), 13 Oct 2023, In: Journal of Global Health. 13, 17 p., 04096.Research output: Contribution to journal › Article › peer-review
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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Sun, J., Zhao, J., Jiang, F., Wang, L., Xiao, Q., Han, F., Chen, J., Yuan, S., Wei, J., Larsson, S. C., Zhang, H., Dunlop, M. G., Farrington, S. M., Ding, K., Theodoratou, E. & Li, X., 19 Sept 2023, In: Genome Medicine. 15, p. 75 13 p., 75.Research output: Contribution to journal › Article › peer-review
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A rapid review on the COVID-19's global impact on breast cancer screening participation rates and volumes from January-December 2020
UNCOVER, International Partnership for Resilience in Cancer Systems (I-PaRCS), Breast Cancer Working Group 2, Lee, R., Xu, W., Dozier, M., McQuillan, R., Theodoratou, E. & Figueroa, J., 12 Sept 2023, (E-pub ahead of print) In: eLIFE. 12, e85680.Research output: Contribution to journal › Article › peer-review
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The Global Trends in Incidence, Death, Burden and Risk Factors of Early-onset Cancer From 1990 to 2019
Zhao, J., Xu, L., Sun, J., Song, M., Wang, L., Yuan, S., Zhu, Y., Wan, Z., Larsson, S. C., Tsilidis, K. K., Dunlop, M. G., Campbell, H., Rudan, I., Song, P., Theodoratou, E., Ding, K. & Li, X., 5 Sept 2023, In: BMJ Oncology. 2, 12 p., e000049.Research output: Contribution to journal › Article › peer-review
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Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk
Zhou, X., Xiao, Q., Jiang, F., Sun, J., Wang, L., Yu, L., Zhou, Y., Zhao, J., Zhang, H., Yuan, S., Timofeeva, M., Spiliopoulou, A., Mesa-Eguiagaray, I., Farrington, S. M., Law, P. J., Houlston, R. S., Ding, K., Dunlop, M. G., Theodoratou, E. & Li, X., 22 Aug 2023, (E-pub ahead of print) In: British Journal of Cancer. 8 p.Research output: Contribution to journal › Article › peer-review
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Development and Validation of Risk Prediction Models for Colorectal Cancer in Patients with Symptoms
Xu, W., Mesa Eguiagaray, I., Kirkpatrick, T., Devlin, J., Brogan, S., Turner, P., Macdonald, C., Thornton, M., Zhang, X., He, Y., Li, X., Timofeeva, M., Farrington, S., Din, F., Dunlop, M. & Theodoratou, E., 29 Jun 2023, In: Journal of personalized medicine. 13, 7, 16 p., 1065.Research output: Contribution to journal › Article › peer-review
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Cross-cancer pleiotropic analysis identifies three novel genetic risk variants for colorectal cancer
Sun, J., Wang, L., Zhou, X., Hu, L., Yuan, S., Bian, Z., Chen, J., Zhu, Y., Farrington, S. M., Campbell, H., Ding, K., Zhang, D., Dunlop, M. G., Theodoratou, E. & Li, X., 15 Jun 2023, In: Human Molecular Genetics. 32, 12, p. 2093-2102Research output: Contribution to journal › Article › peer-review
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Exploring the complex relationship between gut microbiota and risk of colorectal neoplasia using bidirectional Mendelian Randomization analysis
Li, W., Zhou, X., Yuan, S., Wang, L., Sun, J., Chen, J., Xiao, Q., Wan, Z., Zheng, J., Zhang, C-X., Larsson, S. C., Farrington, S. M., Law, P., Houlston, R. S., Tomlinson, I., Ding, K-F., Dunlop, M. G., Theodoratou, E. & Li, X., 1 Jun 2023, In: Cancer Epidemiology, Biomarkers & Prevention. 32, 6, p. 809-817Research output: Contribution to journal › Article › peer-review
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Field synopsis of environmental and genetic risk factors of sporadic early-onset colorectal cancer and advanced adenoma
Zhang, R., Boakye, D., Yang, N., Zhou, X., Zhou, Y., Jiang, F., Yu, L., Wang, L., Sun, J., Yuan, S., Chen, J., Hamilton, A. C., Coleman, H. G., Larsson, S. C., Little, J., Dunlop, M. G., Giovannucci, E., Theodoratou, E. & Li, X., 23 May 2023, In: Cancer Epidemiology, Biomarkers & Prevention.Research output: Contribution to journal › Article › peer-review
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Editorial: in search of environmental risk factors of Crohn's disease and ulcerative colitis with mendelian randomisation-authors' reply
Chen, J., Ruan, X., Yuan, S., Theodoratou, E., Satsangi, J. & Li, X., 13 Apr 2023, In: Alimentary Pharmacology and Therapeutics. 57, 9, p. 1034-1035 2 p.Research output: Contribution to journal › Article › peer-review
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Double faecal immunochemical testing in patients with symptoms suspicious of colorectal cancer
Edinburgh Colorectal Group, 1 Apr 2023, In: British Journal of Surgery. 110, 4, p. 471-480Research output: Contribution to journal › Article › peer-review
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N6-methylandenosine-related gene expression signatures for predicting the overall survival and immune responses of patients with colorectal cancer
Yu, L., Wang, L., Sun, J., Zhou, X., Hu, Y., Hu, L., He, Y., Lin, C., Chen, J., Xu, X., Dunlop, M. G., Theodoratou, E., Ding, K. & Li, X., 3 Mar 2023, In: Frontiers in genetics. 14, p. 885930Research output: Contribution to journal › Article › peer-review
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Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank
Wang, L., Li, X., Montazeri, A., MacFarlane, A. J., Momoli, F., Duthie, S. J., Senekal, M., Mesa Eguiagaray, I., Munger, R. G., Bennett, D., Campbell, H., Rubini, M., McNulty, H., Little, J. & Theodoratou, E., 1 Mar 2023, In: The American Journal of Clinical Nutrition (AJCN). 117, 3, p. 564-575Research output: Contribution to journal › Article › peer-review
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Antioxidants, Minerals, and Vitamins in Relation to Crohn’s disease and Ulcerative Colitis: A Mendelian Randomization Study
Chen, J., Ruan, X., Yuan, S., Deng, M., Zhang, H., Sun, J., Yu, L., Satsangi, J., Larsson, S. C., Theodoratou, E., Wang, X. & Li, X., 1 Feb 2023, In: Alimentary Pharmacology and Therapeutics. 57, 4, p. 399-408Research output: Contribution to journal › Article › peer-review
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Comprehensive Investigation on Associations between Dietary Intake and Blood Levels of Fatty Acids and Colorectal Cancer Risk
Lu, Y., Li, D., Wang, L., Zhang, H., Jiang, F., Zhang, R., Xu, L., Yang, N., Dai, S., Xu, X., Theodoratou, E. & Li, X., 1 Feb 2023, In: Nutrients. 15, 3, 13 p., 730.Research output: Contribution to journal › Article › peer-review
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2022
Bi-directional Mendelian randomization analysis provides evidence for the causal involvement of dysregulation of CXCL9, CCL11 and CASP8 in the pathogenesis of ulcerative colitis
Chen, J., Zhou, Y., Sun, Y., Yuan, S., Kalla, R., Sun, J., Zhao, J., Wang, L., Chen, X., Zhou, X., Dai, S., Zhang, Y., Ho, G-T., Xia, D., Cao, Q., Liu, Z., Larsson, S. C., Wang, X., Ding, K., Halfvarson, J., & 3 others, 28 Dec 2022, (E-pub ahead of print) In: Journal of Crohn's and Colitis.Research output: Contribution to journal › Article › peer-review
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Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
Yuan, S., Yu, L., Gou, W., Wang, L., Sun, J., Li, D., Lu, Y., Cai, X., Yu, H., Yuan, C., Zheng, J., Larsson, S. C., Theodoratou, E. & Li, X., 6 Feb 2022, In: EBioMedicine. 76, p. 103865Research output: Contribution to journal › Article › peer-review
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2021
The effectiveness of non-pharmaceutical interventions in reducing SARS-CoV-2 transmission and COVID-19 incidence and mortality: systematic review and meta-analysis
Talic, S., Shah, S., Wild, H., Gasevic, D., Maharaj, A., Ademi, Z., Li, X., Xu, W., Mesa Eguiagaray, I., Rostron, J., Theodoratou, E., Zhang, X., Motee, A., Liew, D. & Ilic, D., 18 Nov 2021, In: British Medical Journal (BMJ). 2021, 375, e068302.Research output: Contribution to journal › Article › peer-review
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Differential genetic influences over colorectal cancer risk and gene expression in large bowel mucosa: Topographical differences in colorectal cancer risk loci eQTLs
Vaughan‐shaw, P. G., Timofeeva, M., Ooi, L., Svinti, V., Grimes, G., Smillie, C., Blackmur, J. P., Donnelly, K., Theodoratou, E., Campbell, H., Zgaga, L., Din, F. V. N., Farrington, S. M. & Dunlop, M. G., 1 Sept 2021, In: International Journal of Cancer. 149, 5, p. 1100-1108 8 p.Research output: Contribution to journal › Article › peer-review
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Genetically-predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian Randomization Study
Zhang, X., Theodoratou, E., Li, X., Farrington, S. M., Law, P. J., Broderick, P., Walker, M., Kimentidis, Y. C., Rees, J., Houlston, R. S., Tomlinson, I. P. M., Burgess, S., Campbell, H., Dunlop, M. G. & Timofeeva, M., 29 Jan 2021, (E-pub ahead of print) In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance.
He, Y., Timofeeva, M., Zhang, X., Xu, W., Din, F. V. N., Svinti MacLeod, V., Farrington, S. M., Campbell, H., Dunlop, M. G. & Theodoratou, E., 7 Jan 2021, In: International Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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2020
The effect of vitamin D supplementation on survival in patients with colorectal cancer: Systematic review and Meta-analysis of Randomised Controlled Trials
Vaughan-Shaw, P. G., Buijs, L. F., Blackmur, J. P., Theodoratou, E., Zgaga, L., Din, F. V. N., Farrington, S. M. & Dunlop, M. G., 15 Sept 2020, In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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Risk factors and risk prediction models for colorectal cancer metastasis and recurrence: an umbrella review of systematic reviews and meta-analyses of observational studies
Xu, W., He, Y., Wang, Y., Li, X., Young, J., Ioannidis, J. PA., Dunlop, M. & Theodoratou, E., 26 Jun 2020, (E-pub ahead of print) In: BMC Medicine. 18, 1, 172.Research output: Contribution to journal › Article › peer-review
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Non-genetic biomarkers and colorectal cancer risk: umbrella review and evidence triangulation
Zhang, X., Gill, D., He, Y., Yang, T., Li, X., Monori, G., Campbell, H., Dunlop, M., Tsilidis, K. K., Timofeeva, M. & Theodoratou, E., 12 May 2020, In: Cancer Medicine.Research output: Contribution to journal › Article › peer-review
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Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response
Vaughan-Shaw, P. G., Zgaga, L., Ooi, L. Y., Theodoratou, E., Timofeeva, M., Svinti, V., Walker, M., O'Sullivan, F., Ewing, A., Johnston, S., Din, F. V. N., Campbell, H., Farrington, S. M. & Dunlop, M. G., Jan 2020, In: Gut. 69, 1, p. 103-111 9 p.Research output: Contribution to journal › Article › peer-review
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2019
Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer
Montazeri, Z., Li, X., Nyiraneza, C., Ma, X., Timofeeva, M., Svinti MacLeod, V., Meng, X., He, Y., Bo, Y., Morgan, S., Castellví-Bel, S., Ruiz-Ponte, C., Fernandez-Rozadilla, C., Carracedo, A., Farrington, S., Dunlop, M., Campbell, H. & Theodoratou, E., 9 Dec 2019, (E-pub ahead of print) In: Gut.Research output: Contribution to journal › Article › peer-review
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Effects of common genetic variants associated with colorectal cancer risk on survival outcomes after diagnosis: a large population-based cohort study.
He, Y., Theodoratou, E., Li, X., Din, F. V. N., Vaughan-Shaw, P., Svinti, V., Farrington, S. M., Campbell, H., Dunlop, M. G. & Timofeeva, M., 1 Nov 2019, In: International Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study
Li, X., Meng, X., He, Y., Spiliopoulou, A., Timofeeva, M., Wei, W-Q., Gifford, A., Yang, T., Varley, T., Tzoulaki, I., Joshi, P., Denny, J. C., Mckeigue, P., Campbell, H. & Theodoratou, E., 18 Oct 2019, In: PLoS Medicine. 16, 10, p. e1002937Research output: Contribution to journal › Article › peer-review
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Phenome Wide Mendelian Randomisation Study of genetically determined Vitamin D on multiple health outcomes using the UK Biobank Study
Meng, X., Li, X., Timofeeva, M., He, Y., Spiliopoulou, A., Wei, W-Q., Gifford, A., Wu, H., Varley, T., Joshi, P., Denny, J. C., Farrington, S. M., Zgaga, L., Dunlop, M. G., McKeigue, P., Campbell, H. & Theodoratou, E., 13 Sept 2019, (E-pub ahead of print) In: International Journal of Epidemiology.Research output: Contribution to journal › Article › peer-review
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Performance of prediction models on survival outcomes of colorectal cancer with surgical resection: A systematic review and meta-analysis
He, Y., Ong, Y., Li, X., Din, F. V., Brown, E., Timofeeva, M., Wang, Z., Farrington, S. M., Campbell, H., Dunlop, M. G. & Theodoratou, E., Jun 2019, In: Surgical Oncology. 29, p. 196-202 7 p.Research output: Contribution to journal › Article › peer-review
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2018
Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study
He, Y., Timofeeva, M., Farrington, S. M., Vaughan-Shaw, P., Svinti, V., Walker, M., Zgaga, L., Meng, X., Li, X., Spiliopoulou, A., Jiang, X., Hyppönen, E., Kraft, P., Kiel, D. P., The SUNLIGHT Consortium, Hayward, C., Campbell, A., Porteous, D., Vucic, K., Kirac, I., & 8 others, 14 Aug 2018, In: BMC Medicine. 16, 142.Research output: Contribution to journal › Article › peer-review
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Plasma N-glycans in colorectal cancer risk
Doherty, M., Theodoratou, E., Walsh, I., Adamczyk, B., Stöckmann, H., Agakov, F., Timofeeva, M., Trbojević-Akmačić, I., Vučković, F., Duffy, F., McManus, C. A., Farrington, S. M., Dunlop, M. G., Perola, M., Lauc, G., Campbell, H. & Rudd, P. M., 5 Jun 2018, In: Scientific Reports. 8, 1, p. 8655Research output: Contribution to journal › Article › peer-review
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2017
Nature, Nurture, and Cancer Risks: Genetic and Nutritional Contributions to Cancer
Theodoratou, E., Timofeeva, M., Li, X., Meng, X. & Ioannidis, J. P. A., 21 Aug 2017, In: Annual Review of Nutrition. 37, p. 293-320 28 p.Research output: Contribution to journal › Article › peer-review