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Decoding senescent cell signalling pathways in tissue fibrosis
Ferenbach, David
(Principal Investigator)
School of Regeneration and Repair
Overview
Fingerprint
Research output
(2)
Project Details
Status
Active
Effective start/end date
1/04/23
→
31/03/28
Funding
Medical Research Council:
£2,496,854.01
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Nephropathy
Medicine and Dentistry
100%
Chronic Kidney Disease
Medicine and Dentistry
66%
Epithelial Cell
Medicine and Dentistry
50%
Urinary System
Medicine and Dentistry
50%
Clusterin
Medicine and Dentistry
50%
Biological Marker
Medicine and Dentistry
50%
Immunofluorescence
Medicine and Dentistry
41%
Creatinine
Medicine and Dentistry
33%
Research output
Research output per year
2025
2025
2025
2
Article
Research output per year
Research output per year
Urinary Clusterin is a Biomarker of Renal Epithelial Senescence and Predicts Human Kidney Disease Progression
Baird, D. P., Reck, M.,
Campbell, R.
, Docherty, M.-H.,
Janas, P. P.
, Mason, T.,
Mortuza, Z.
,
Vermeren, M.
, Nam, A., Yang, W., Schurman, N., Williams, C., Traynor, J. P., Mark, P. B.,
Mylonas, K. J.
,
Hughes, J.
,
Denby, L.
,
Conway, B. R.
&
Ferenbach, D. A.
,
Jul 2025
,
In:
Kidney International Reports.
10
,
7
,
p. 2344-2356
13 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Biological Marker
100%
Urinary System
100%
Nephropathy
100%
Clusterin
100%
Creatinine
66%
Multiomic analysis of human kidney disease identifies a tractable inflammatory and pro-fibrotic tubular cell phenotype
Reck, M., Baird, D. P., Veizades, S., Sutherland, C., Bell, R. M. B., Hur, H., Cairns, C.,
Janas, P. P.
, Campbell, R., Nam, A., Yang, W., Schurman, N., Williams, C., O'Sullivan, E.,
Beniazza, M.
, Corsinotti, A.,
Bellamy, C.
,
Hughes, J.
, Laird, A. &
Denby, L.
& 3 others
,
Chandra, T.,
Ferenbach, D. A.
&
Conway, B. R.
,
22 May 2025
,
In:
Nature Communications.
16
, 4745.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Nephropathy
100%
Epithelial Cell
100%
Chronic Kidney Disease
100%
Molecular Imaging
50%
Receptor
50%