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Defining the pathway of biomarkers for pharmacodynamics, efficacy and toxicity for 11B-HSD1 inhibition in metabolic disease indications
Walker, Brian
(Principal Investigator)
Andrew, Ruth
(Co-investigator)
Critchley, Hilary
(Co-investigator)
Jansen, Maurits
(Co-investigator)
Reynolds, Rebecca
(Co-investigator)
Seckl, Jonathan
(Co-investigator)
Deanery of Clinical Sciences
Centre for Cardiovascular Science
MRC Centre for Reproductive Health
Edinburgh Imaging
Overview
Fingerprint
Research output
(1)
Project Details
Status
Finished
Effective start/end date
1/04/07
→
30/06/12
Funding
UK industry, commerce and public corporations:
£1,112,195.00
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Glucocorticoid
Chemical Compounds
100%
Cortisol
Chemical Compounds
99%
Glucocorticoids
Medicine & Life Sciences
70%
Hydrocortisone
Medicine & Life Sciences
68%
Adipose Tissue
Medicine & Life Sciences
64%
11-beta-Hydroxysteroid Dehydrogenase Type 1
Medicine & Life Sciences
41%
Plasma
Chemical Compounds
26%
Adrenal Cortex Hormone
Chemical Compounds
11%
Research output
Research output per year
2010
2010
2010
1
Article
Research output per year
Research output per year
Glucocorticoids Turn Over Slowly in Human Adipose Tissue in Vivo
Hughes, K. A.
,
Reynolds, R. M.
,
Andrew, R.
,
Critchley, H. O. D.
&
Walker, B. R.
,
Oct 2010
,
In:
Journal of Clinical Endocrinology & Metabolism.
95
,
10
,
p. 4696-4702
7 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Glucocorticoid
100%
Cortisol
99%
Glucocorticoids
70%
Hydrocortisone
68%
Adipose Tissue
64%