DENOVOMUT: An integrated approach to understanding the impact of de novo mutations on the mammalian genome

Keightley, Peter (Principal Investigator)

School of Biological Sciences

Status	Finished
Effective start/end date	1/01/17 → 31/07/24

Funding

European Commission: £1,421,978.83

3 Article

The rate and spectrum of new mutations in mice inferred by long-read sequencing
López-Cortegano, E., Chebib, J., Jonas, A., Vock, A., Künzel, S., Keightley, P. D. & Tautz, D., Jan 2025, In: Genome Research. 35, 1, p. 43-54 52 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection
Chebib, J., Jonas, A., López-Cortegano, E., Künzel, S., Tautz, D. & Keightley, P. D., 26 Sept 2024, In: PLoS Biology. 22, 9, 20 p., e3002795.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Variation in the spectrum of new mutations among inbred strains of mice
López-Cortegano, E., Chebib, J., Jonas, A., Vock, A., Künzel, S., Tautz, D. & Keightley, P. D., Aug 2024, In: Molecular Biology and Evolution. 41, 8, 35 p., msae163.
Research output: Contribution to journal › Article › peer-review

Open Access
File

An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection: Dataset
Chebib, J. (Creator), Lopez Cortegano, E. (Creator) & Keightley, P. (Project Manager), Zenodo, 19 Jul 2024
DOI: 10.5281/zenodo.12783268
Dataset