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Determining the effects of ageing on the innate mucosal immune system
Mabbott, Neil
(Principal Investigator)
Royal (Dick) School of Veterinary Studies
Edinburgh Imaging
Overview
Fingerprint
Research output
(6)
Project Details
Status
Finished
Effective start/end date
1/11/15
→
31/10/18
Funding
BBSRC:
£470,863.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Peyer's Patches
Medicine & Life Sciences
100%
Paneth Cells
Medicine & Life Sciences
77%
antigens
Physics & Astronomy
52%
macrophages
Physics & Astronomy
51%
Macrophage Colony-Stimulating Factor
Medicine & Life Sciences
50%
Macrophages
Medicine & Life Sciences
49%
stem cells
Physics & Astronomy
48%
Stem Cell Niche
Medicine & Life Sciences
45%
Research output
Research output per year
2016
2016
2018
2019
2020
2021
2021
6
Article
Research output per year
Research output per year
Aging-related impairments to M cells in Peyer's patches coincide with disturbances to Paneth cells
Donaldson, D.
,
Shih, B.
&
Mabbott, N.
,
6 Dec 2021
, (E-pub ahead of print)
In:
Frontiers in Immunology.
12
, 761949.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Paneth Cells
100%
Peyer's Patches
89%
Epithelium
52%
Cell Differentiation
33%
Intestines
24%
Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice
Donaldson, D. S.
,
Pollock, J.
,
Vohra, P.
,
Stevens, M.
&
Mabbott, N.
,
26 Jun 2020
,
In:
iScience.
23
,
6
,
p. 1-19
19 p.
, 101147.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
mice
100%
Peyer's patches
95%
intestinal microorganisms
69%
cells
54%
oral vaccination
49%
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome
Komban, R. J.
,
Stromberg, A.
,
Biram, A.
,
Cervin, J.
,
Lebrero-Fernandez, C.
,
Mabbott, N.
,
Yrlid, U.
,
Shulman, Z.
,
Bemark, M.
&
Lycke, N.
,
3 Jun 2019
,
In:
Nature Communications.
10
,
p. 1-15
15 p.
, 2423 (2019).
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Peyer's Patches
100%
antigens
97%
domes
90%
Antigen
64%
B-Lymphocytes
59%