Development and characterisation: new transgenic mouse model to study link between prp and alzheimers disease

Manson, Jean (Principal Investigator)

Deanery of Clinical Sciences

Status	Finished
Effective start/end date	1/11/09 → 31/10/11

Funding

UK-based charities: £29,952.00

3 Article

Ablation of prion protein in wild type human amyloid precursor protein (APP) transgenic mice does not alter the proteolysis of APP, levels of amyloid-β or pathologic phenotype
Whitehouse, I., Brown, D., Baybutt, H., Diack, A., Piccardo, P., Manson, J. & Hooper, N. M., 22 Jul 2016, (E-pub ahead of print) In: PLoS ONE. 11, 7, e0159119.
Research output: Contribution to journal › Article › peer-review

Open Access
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Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain
Lewis, V., Whitehouse, I. J., Baybutt, H., Manson, J. C., Collins, S. J. & Hooper, N. M., 21 Feb 2012, In: PLoS ONE. 7, 2, 8 p., ARTN e31754.
Research output: Contribution to journal › Article › peer-review

Open Access
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Prion protein interacts with bace1 and differentially regulates its activity towards wild type and swedish mutant amyloid precursor protein
Griffiths, H. H., Whitehouse, I. J., Baybutt, H., Brown, D., Kellett, K. A., Jackson, C. D., Turner, A. J., Piccardo, P., Manson, J. C. & Hooper, N. M., 2011, In: Journal of Biological Chemistry. 286, 38, p. 33489-33500
Research output: Contribution to journal › Article › peer-review

Open Access
File