Research output per year
Research output per year
- 13 results
Search results
-
2025
TET knockout cells transit between pluripotent states and exhibit precocious germline entry
Pantier, R., Barbieri, E., Gonzalez Brito, S., Thomson, E., Tatar, T., Colby, D., Zhang, M. & Chambers, I., 1 Dec 2025, In: EMBO Journal. 44, 23, p. 7060-7089 30 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
NANOG is repurposed after implantation to repress Sox2 and begin pluripotency extinction
Wong, F. C. K., Zhang, M., Thomson, E., Schumacher, L. J., Tsakiridis, A., Ashmore, J., Tong, L., Blin, G., Karagianni, E., Mullin, N. P., Chambers, I. & Wilson, V., 1 Oct 2025, In: The EMBO journal. 44, 19, p. 5337-5374 64 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2021
Phosphorylation of NANOG by CASEIN KINASE I regulates embryonic stem cell self-renewal
Mullin, N. P., Varghese, J., Colby, D., Richardson, J. M., Findlay, G. M. & Chambers, I., 15 Jan 2021, In: FEBS Letters. 595, 1, p. 14-25 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2020
TET1 interacts directly with NANOG via independent domains containing hydrophobic and aromatic residues
Pantier, R., Mullin, N. P., Hall-Ponsele, E. & Chambers, I., 20 Nov 2020, In: Journal of Molecular Biology. 432, 23, p. 6075-6091Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2019
Segregation of the mouse germline and soma
Zhang, M. & Chambers, I., 4 Oct 2019, (E-pub ahead of print) In: Cell Cycle. 18, 22, p. 3064-3071Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Endogenous epitope-tagging of Tet1, Tet2 and Tet3 identifies TET2 as a naïve pluripotency marker
Pantier, R., Tatar, T., Colby, D. & Chambers, I., 3 Oct 2019, In: Life Science Alliance. 2, 5, e201900516.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation
Festuccia, N., Halbritter, F., Corsinotti, A., Gagliardi, A., Colby, D., Tomlinson, S. R. & Chambers, I., 2 Nov 2018, In: EMBO Journal. 37, 21, 20 p., e95476.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
OTX2 restricts entry to the mouse germline
Zhang, J., Zhang, M., Acampora, D., Vojtek, M., Yuan, D., Simeone, A. & Chambers, I., 3 Oct 2018, In: Nature. 562, p. 595-599 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signaling in preimplantation mouse embryos
Mistri, T. K., Arindrarto, W., Ng, W. P., Wang, C., Lim, L. H., Sun, L., Chambers, I., Wohland, T. & Robson, P., 20 Mar 2018, In: Biochemical Journal. 475, 6, p. 1075-1089 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Esrrb complementation rescues development of nanog-null germ cells
Zhang, M., Leitch, H. G., Tang, W. W. C., Festuccia, N., Hall-Ponsele, E., Nichols, J., Surani, M. A., Smith, A. & Chambers, I., 9 Jan 2018, In: Cell Reports. 22, 2, p. 332-339 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2017
Distinct SoxB1 networks are required for naïve and primed pluripotency
Corsinotti, A., Wong, F. C. K., Tatar, T., Szczerbinska, I., Halbritter, F., Colby, D., Gogolok, S., Pantier, R., Liggat, K., Mirfazeli, E. S., Hall-Ponsele, E., Mullin, N. P., Wilson, V. & Chambers, I., 19 Dec 2017, In: eLIFE. 6, 28 p., e27746.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function
Mullin, N., Gagliardi, A., Khoa, L. T. P., Colby, D., Hall-Ponsele, E., Lowe, A. J. & Chambers, I., 19 May 2017, In: Journal of Molecular Biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2015
Lessons in learning: An effective process for engaging 12- to 14-year-olds in stem cell biology
Kemp, E. & Chambers, I., Jan 2015, In: EMBO Reports. 16, 1, p. 7-13 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile