Elucidating RNA metabolism changes underlying the progressive neural cell biology of ALS

Sibley, Chris (Principal Investigator)

School of Biological Sciences

Status	Finished
Effective start/end date	9/05/19 → 30/04/24

Funding

UK-based charities: £1,428,756.00

6 Article

Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice
Paterson, H., Yu, S., Artigas, N., Prado, M., Haberman, N., Wang, Y-F., Jobbins, A., Pahita, E., Mokochinski, J., Hall, Z., Guerin, M., Paulo, J., Ng, S. S., Villarroya, F., Rashid, S. T., Goff, W. L., Lenhard, B., Cebola, I., Finley, D., Gygi, S., & 2 othersSibley, C. R. & Vernia, S., 19 Dec 2022, In: Nature Metabolism. 4, 12, p. 1812-1829 39 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72‐ALS
Rifai, O. M., Longden, J., O'Shaughnessy, J., Sewell, M. D. E., Pate, J., McDade, K., Daniels, M. J. D., Abrahams, S., Chandran, S., McColl, B. W., Sibley, C. R. & Gregory, J. M., 1 Dec 2022, In: The Journal of Pathology. 258, 4, p. 366-381 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis
Taha, D., Clarke, B., Hall, C., Tyzack, G., Ziff, O., Greensmith, L., Kalmar, B., Ahmed, M., Alam, A., Thelin, E. P., Garcia, N., Helmy, A., Sibley, C. R. & Patani, R., 1 Feb 2022, In: Brain. 145, 2, p. 481-489 43 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File