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Expoiting adhesion protein networks in glioblastoma
Frame, Margaret
(Principal Investigator)
Brunton, Val
(Co-investigator)
Byron, Adam
(Co-investigator)
Pollard, Steven
(Co-investigator)
Deanery of Molecular, Genetic and Population Health Sciences
Deanery of Clinical Sciences
Overview
Fingerprint
Research output
(9)
Project Details
Status
Active
Effective start/end date
1/05/18
→
30/04/23
Funding
UK-based charities:
£2,447,966.00
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Focal Adhesion Protein-Tyrosine Kinases
Medicine & Life Sciences
100%
AZD-0424
Medicine & Life Sciences
65%
Neoplasms
Medicine & Life Sciences
53%
nifuroxazide
Medicine & Life Sciences
50%
Interleukin-33
Medicine & Life Sciences
36%
trametinib
Medicine & Life Sciences
35%
Chromatin
Medicine & Life Sciences
35%
Mitogen-Activated Protein Kinase Kinases
Medicine & Life Sciences
33%
Research output
Research output per year
2018
2020
2021
2022
9
Article
Research output per year
Research output per year
Characterisation of a nucleo-adhesome
Byron, A.
,
Griffith, B.
,
Herrero Mier, A.
,
Loftus, A. E. P.
,
Koeleman, E. S.
,
Kogerman, L.
,
Dawson, J. C.
,
McGivern, N.
,
Culley, J.
,
Grimes, G. R.
,
Serrels, B.
,
von Kriegsheim, A.
,
Brunton, V. G.
&
Frame, M. C.
,
1 Jun 2022
, (E-pub ahead of print)
In:
Nature Communications.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
proteins
100%
Nuclear Proteins
97%
adhesion
90%
characterization
69%
Protein
51%
Pathway profiling of a novel SRC inhibitor, AZD0424, in combination with MEK inhibitors
Dawson, J. C.
,
Munro, A.
,
Macleod, K.
,
Muir, M.
,
Timpson, P.
,
Williams, R. J.
,
Frame, M. C.
,
Brunton, V. G.
&
Carragher, N. O.
,
2 Dec 2021
, (E-pub ahead of print)
In:
Molecular Oncology.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
AZD-0424
100%
trametinib
54%
Mitogen-Activated Protein Kinase Kinases
44%
AZD 6244
19%
Cell Line
13%
ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
Bolado-carrancio, A.
,
Lee, M.
,
Ewing, A.
,
Muir, M.
,
Macleod, K. G.
,
Gallagher, W. M.
,
Nguyen, L. K.
,
Carragher, N. O.
,
Semple, C. A.
,
Brunton, V. G.
,
Caswell, P. T.
&
Von Kriegsheim, A.
,
23 Sep 2021
, (E-pub ahead of print)
In:
Oncogene.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Recycling
100%
Drive
89%
ErbB Receptors
82%
Breast Neoplasms
55%
Guanine Nucleotide Dissociation Inhibitors
45%