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Fibroblast activation protein expressing cancer associated fibroblasts from lung cancer as imaging biomarkers for immunotherapy stratification
Akram, Ahsan
(Principal Investigator)
Deanery of Clinical Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/12/17
→
29/02/24
Funding
Cancer Research UK:
£1,167,793.52
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Cancer Associated Fibroblast
Medicine and Dentistry
100%
Non Small Cell Lung Cancer
Medicine and Dentistry
78%
T Cell
Medicine and Dentistry
64%
Tumor Necrosis Factor
Medicine and Dentistry
50%
Secretion (Process)
Medicine and Dentistry
50%
Transforming Growth Factor Beta
Medicine and Dentistry
50%
CXCL13
Immunology and Microbiology
50%
Fibroblast
Biochemistry, Genetics and Molecular Biology
50%
Research output
Research output per year
2023
2023
2025
2025
2
Article
Research output per year
Research output per year
IFNγ and TNFα drive an inflammatory secretion profile in cancer associated fibroblasts from human non-small cell lung cancer
Koppensteiner, L.
,
Mathieson, L.
,
Neilson, L.
,
O'Connor, R. A.
&
Akram, A. R.
,
1 Jan 2025
,
In:
FEBS Letters.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Secretion (Process)
100%
Tumor Necrosis Factor
100%
Non Small Cell Lung Cancer
100%
Cancer Associated Fibroblast
100%
Fibroblast
100%
Cancer-associated fibroblasts drive CXCL13 production in activated T cells via TGF-beta
O'Connor, R. A.
,
Martinez, B. R.
,
Koppensteiner, L.
,
Mathieson, L.
&
Akram, A. R.
,
13 Jul 2023
,
In:
Frontiers in Immunology.
14
, 1221532.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
T Cell
100%
Cancer Associated Fibroblast
100%
Transforming Growth Factor Beta
100%
CXCL13
100%
Non Small Cell Lung Cancer
57%