How does 11 beta-hydroxysteroid dehydrogenase type 1 deficiency protect against age-related cognitive impairments

Yau, Joyce (Principal Investigator)

Project Details

Status	Finished
Effective start/end date	6/01/07 → 30/06/11

Funding

MRC: £621,868.00

6 Article
2 Literature review

Cognitive and disease-modifying effects of 11ß-hydroxysteroid dehydrogenase type 1 inhibition in male Tg2576 mice, a model of Alzheimer's disease
Sooy, K., Noble, J., McBride, A., Binnie, M., Yau, J. L. W., Seckl, J. R., Walker, B. R. & Webster, S. P., 25 Aug 2015, In: Endocrinology.
Research output: Contribution to journal › Article › peer-review

Open Access
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Decreased Npas4 and Arc mRNA levels in the hippocampus of aged memory-impaired wild type but not memory preserved 11β-HSD1 deficient mice
Qiu, J., Dunbar, D. R., Noble, J., Cairns, C., Carter, R., Kelly, V., Chapman, K. E., Seckl, J. R. & Yau, J. L. W., 13 Nov 2015, In: Journal of Neuroendocrinology. 28, 1
Research output: Contribution to journal › Article › peer-review

Open Access
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Diurnal and stress-induced intra-hippocampal corticosterone rise attenuated in 11β-HSD1-deficient mice: a microdialysis study in young and aged mice
Yau, J. L. W., Noble, J., Kenyon, C. J., Ludwig, M. & Seckl, J. R., Mar 2015, In: European Journal of Neuroscience. 41, 6, p. 787-92 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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