Identification and prediction of coronary artery plaque rupture using 18F-fluoride positron emission tomography

2020

18F-Fluoride PET/MR in cardiac amyloid; a comparison study with aortic stenosis and age and sex matched controls

Andrews, J., Giovanni Trivieri, M., Everett, R., Spath, N., Macnaught, G., Moss, A. J., Doris, M., Pawade, T., van Beek, E. J. R., Lucatelli, C., Newby, D. E., Robson, P., Fayad, Z. A. & Dweck, M. R., 30 Sept 2020, (E-pub ahead of print) In: Journal of Nuclear Cardiology.

Research output: Contribution to journal › Article › peer-review

Open Access

Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism

Macaskill, M., Stadulyte, A., Williams, L., Morgan, T. E. F., Sloan, N. L., Corral, C. A., Walton, T., Wimberley, C., McKenzie, C-A., Spath, N., Mungall, W., Bouhaidar, R., Dweck, M. R., Gray, G., Newby, D. E., Lucatelli, C., Sutherland, A., Pimlott, S. & Tavares, A. A. S., 28 Aug 2020, (E-pub ahead of print) In: Journal of Nuclear Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy

Kwiecinski, J., Lennen, R. J., Gray, G., Borthwick, G., Boswell, L., Baker, A. H., Newby, D. E., Dweck, M. R. & Jansen, M., 6 Aug 2020, In: Journal of Cardiovascular Magnetic Resonance.

Research output: Contribution to journal › Article › peer-review

Open Access

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Eosinophil deficiency promotes aberrant repair and adverse remodelling following acute myocardial infarction

Toor, I., Rückerl, D., Mair, I., Ainsworth, R., Meloni, M., Spiroski, A-M., Benezech, C., Felton, J. M., Thomson, A. W., Caporali, A., Keeble, T., Tang, K. H., Rossi, A., Newby, D., Allen, J. E. & Gray, G., 8 Jul 2020, (E-pub ahead of print) In: JACC: Basic to Translational Science.

Research output: Contribution to journal › Article › peer-review

Open Access

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Respiration-averaged CT versus standard CT attenuation maps for correction of the 18F-NaF uptake in hybrid PET/CT

Tzolos, E., Lassen, M. L., Pan, T., Kwiecinski, J., Cadet, S., Dey, D., Dweck, M. R., Newby, D. E., Berman, D. & Slomka, P., 2 Jul 2020, In: Journal of Nuclear Cardiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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Ticagrelor to Reduce Myocardial Injury in Patients With High-Risk Coronary Artery Plaque

Moss, A. J., Dweck, M. R., Doris, M. K., Andrews, J. P. M., Bing, R., O. Forsythe, R., Cartlidge, T. R., Pawade, T. A., Daghem, M., Raftis, J. B., Williams, M. C., van Beek, E. J. R., Forsyth, L., Lewis, S. C., Lee, R. J., Shah, A. S. V., Mills, N. L., Newby, D. E. & Adamson, P. D., Jul 2020, In: Journal of the American College of Cardiology. 13, 7, p. 1549-1560

Research output: Contribution to journal › Article › peer-review

Open Access

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Coronary 18F-Sodium Fluoride Uptake Predicts Outcomes in Patients With Coronary Artery Disease

Kwiecinski, J., Tzolos, E., Adamson, P., Cadet, S., Moss, A., Joshi, N., Williams, M., van Beek, E., Dey, D., Berman, D., Newby, D., Slomka, P. & Dweck, M., 23 Jun 2020, In: Journal of the American College of Cardiology. 75, 24, p. 3061-3074

Research output: Contribution to journal › Article › peer-review

Open Access

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Assessment of different quantification metrics of [18F]-NaF PET/CT images of patients with abdominal aortic aneurysm

Akerele, M. I., Mushari, N. A., Forsythe, R., Syed, M., Karakatsanis, N. A., Newby, D., Dweck, M. & Tsoumpas, C., 17 Jun 2020, In: Journal of Nuclear Cardiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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CLINICAL ENDPOINT ADJUDICATION

Meah, M., Denvir, M., Mills, N., Norrie, J. & Newby, D., 13 Jun 2020, In: The Lancet.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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Observer repeatability and interscan reproducibility of 18F-sodium fluoride coronary microcalcification activity

Tzolos, E., Kwiecinski, J., Lyngby Lassen, M., Cadet, S., Adamson, P., Moss, A., Joshi, N., Williams, M., van Beek, E., Dey, D., Berman, D. S., Dweck, M., Newby, D. & Slomka, P., 11 Jun 2020, (E-pub ahead of print) In: Journal of Nuclear Cardiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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We all breathe the same air …. and we are all mortal

Miller, M., Shah, A. & Newby, D., 18 May 2020, In: Cardiovascular Research.

Research output: Contribution to journal › Article › peer-review

Open Access

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Incidence, microbiology and outcomes in patient hospitalized with infective endocarditis

Shah, A., Mcallister, D., Gallacher, P., Astengo, F., Rodriguez Perez, J. A., Hall, J., Lee, K. K., Bing, R., Anand, A., Nathwani, D., Mills, N., Newby, D., Marwick, C. & Cruden, N., 15 May 2020, In: Circulation.

Research output: Contribution to journal › Article › peer-review

Open Access

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Chest pain - when in doubt

Bing, R., Mitchell, A. & Newby, D., 14 Apr 2020, In: Heart.

Research output: Contribution to journal › Article › peer-review

Open Access

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Innovation in Medical Imaging To Improve Disease Staging, Therapeutic Intervention, and Clinical Outcomes

Daghem, M. & Newby, D., 25 Mar 2020, (E-pub ahead of print) In: Atherosclerosis. 306, p. 75-84

Research output: Contribution to journal › Review article › peer-review

Open Access

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Validation of European Society of Cardiology pre-test probabilities for obstructive coronary artery disease in suspected stable angina

Bing, R., Singh, T., Dweck, M. R., Mills, N. L., Williams, M. C., Adamson, P. D. & Newby, D. E., 24 Jan 2020, In: European Heart Journal - Quality of Care and Clinical Outcomes.

Research output: Contribution to journal › Article › peer-review

Open Access

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2019

High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome

High-STEACS Investigators, Bularga, A., Lee, K. K., Stewart, S., Ferry, A. V., Chapman, A. R., Marshall, L., Strachan, F. E., Cruickshank, A., Maguire, D., Berry, C., Findlay, I., Shah, A. S. V., Newby, D. E., Mills, N. L. & Anand, A., 5 Nov 2019, In: Circulation. 140, 19, p. 1557–1568

Research output: Contribution to journal › Article › peer-review

Open Access

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Plasma Desmosine and Abdominal Aortic Aneurysm Disease

Mordi, I. R., Forsythe, R., Gellatly, C., Iskandar, Z., McBride, O., Saratzis, A., Chalmers, R., Chin, C., Bown, M. J., Newby, D., Lang, C. C., Huang, J. T. J. & Choy, A. M., 9 Oct 2019, In: Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease.

Research output: Contribution to journal › Article › peer-review

Open Access

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Ferumoxytol-enhanced Magnetic Resonance Imaging in Patients with Prior Cardiac Transplantation

Stirrat, C., Alam, S., MacGillivray, T., Gray, C., Dweck, M., Jones, V., Wallace, W., Payne, J., Prasad, S., Gardner, R. S., Petrie, M. C., Mirsadraee, S., Henriksen, P., Semple, S. & Newby, D., 3 Oct 2019, In: Open heart. 6, 2

Research output: Contribution to journal › Article › peer-review

Open Access

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Global burden of atherosclerotic cardiovascular disease in people with hepatitis C virus infection: a systematic review, meta-analysis, and modelling study

Lee, K. K., Stelzle, D., Bing, R., Anwar, M., Strachan, F., Bashir, S., Newby, D. E., Shah, J. S., Chung, M. H., Bloomfield, G. S., Longenecker, C. T., Bagchi, S., Kottilil, S., Blach, S., Razavi, H., Mills, P. R., Mills, N. L., McAllister, D. A. & Shah, A. S. V., 1 Oct 2019, In: The Lancet Gastroenterology & Hepatology. 4, 10, p. 794-804

Research output: Contribution to journal › Article › peer-review

Open Access

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Non-invasive in vivo imaging of acute thrombosis: development of a novel factor XIIIa radiotracer

Andrews, J., Portal, C., Walton, T., Macaskill, M., Hadoke, P., Corral, C. A., Lucatelli, C., Wilson, S., Macnaught, G., Dweck, M., Newby, D. & Tavares, A., 13 Aug 2019, In: European Heart Journal - Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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Standardized reporting systems for computed tomography coronary angiography and calcium scoring: A real-world validation of CAD-RADS and CAC-DRS in patients with stable chest pain

Williams, M. C., Moss, A., Dweck, M., Hunter, A., Pawade, T., Adamson, P., Shah, A. S. V., Alam, S., Maroules, C. D., Van Beek, E. J., Cury, R., Nicol, E. D., Newby, D. E. & Roditi, G., 26 Jul 2019, (E-pub ahead of print) In: Journal of Cardiovascular Computed Tomography.

Research output: Contribution to journal › Article › peer-review

Open Access

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Manganese-enhanced MRI of the myocardium

Spath, N., Thompson, G., Baker, A., Dweck, M., Newby, D. & Semple, SI., 23 Jul 2019, In: Heart.

Research output: Contribution to journal › Review article › peer-review

Open Access

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Clinical determinants of plasma cardiac biomarkers in patients with stable chest pain

Bing, R., Henderson, J., Hunter, A. L., Williams, M., Moss, A., Shah, A. S., McAllister, D., Dweck, M., Newby, D., Mills, N. & Adamson, P., 1 Jun 2019, In: Heart.

Research output: Contribution to journal › Article › peer-review

Open Access

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Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice

Toor, I. S., Rückerl, D., Mair, I., Thomson, A., Rossi, A. G., Newby, D. E., Allen, J. E. & Gray, G. A., 23 May 2019, (E-pub ahead of print) In: Clinical & Experimental Immunology.

Research output: Contribution to journal › Article › peer-review

Open Access

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Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

Zheng, K. H., Tsimikas, S., Pawade, T., Kroon, J., Jenkins, W. S. A., Doris, M. K., White, A. C., Timmers, N. K. L. M., Hjortnaes, J., Rogers, M. A., Aikawa, E., Arsenault, B. J., Witztum, J. L., Newby, D. E., Koschinsky, M. L., Fayad, Z. A., Stroes, E. S. G., Boekholdt, S. M. & Dweck, M. R., 7 May 2019, In: Journal of the American College of Cardiology. 73, 17, p. 2150-2162

Research output: Contribution to journal › Article › peer-review

Open Access

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Breast arterial calcification on mammography and risk of coronary artery disease: A SCOT-HEART sub-study

McLenachan, S., Camilleri, F., Smith, M., Newby, D. & Williams, M., 22 Feb 2019, In: Clinical Radiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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¹⁸F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images

Creager, M. D., Hohl, T., Hutcheson, J. D., Moss, A. J., Schlotter, F., Blaser, M. C., Park, M-A., Lee, L. H., Singh, S. A., Alcaide Corral, C., Tavares, A. A. S., Newby, D. E., Kijewski, M. F., Aikawa, M., Di Carli, M., Dweck, M. R. & Aikawa, E., 15 Jan 2019, In: Circulation: Cardiovascular Imaging. 12, 1, e007835.

Research output: Contribution to journal › Article › peer-review

Open Access

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2018

Manganese-enhanced T1 mapping in the myocardium of normal and infarcted hearts.

Spath, N., Lilburn, D., Gray, G., Le Page, L., Papanastasiou, G., Lennen, R. J., Janiczek, R. L., Dweck, M., Newby, D., Yang, P., Jansen, M., Semple, S. & Dweck, M., 25 Oct 2018, In: Contrast Media and Molecular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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High-Sensitivity Cardiac Troponin I and Clinical Risk Scores in Patients With Suspected Acute Coronary Syndrome

Chapman, A. R., Hesse, K., Andrews, J., Ken Lee, K., Anand, A., Shah, A. S. V., Sandeman, D., Ferry, A. V., Jameson, J., Piya, S., Stewart, S., Marshall, L., Strachan, F. E., Gray, A., Newby, D. E. & Mills, N. L., 16 Oct 2018, In: Circulation. 138, 16, p. 1654-1665

Research output: Contribution to journal › Article › peer-review

Open Access

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Comparison of International Guidelines for Assessment of Suspected Stable Angina: Insights From the PROMISE and SCOT-HEART

Adamson, P., Newby, D., Hill, C. L., Coles, A., Douglas, P. S. & Fordyce, C. B., Sept 2018, In: JACC: Cardiovascular Imaging. 11, 9, p. 1301-1310 10 p.

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Open Access

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Short-Term Hemodynamic Effects of Apelin in Patients With Pulmonary Arterial Hypertension

Brash, L., Barnes, G. D., Brewis, M. J., Church, A. C., Gibbs, S. J., Howard, L. S. G. E., Jayasekera, G., Johnson, M. K., McGlinchey, N., Onorato, J., Simpson, J., Stirrat, C., Thomson, S., Watson, G., Wilkins, M. R., Xu, C., Welsh, D. J., Newby, D. E. & Peacock, A. J., 28 Mar 2018, (E-pub ahead of print) In: JACC: Basic to Translational Science. 3, 2, p. 176-186 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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High-Sensitivity Cardiac Troponin I and the Diagnosis of Coronary Artery Disease in Patients With Suspected Angina Pectoris

Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S. V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J. R., Dweck, M. R., Mickley, H., Mills, N. L. & Newby, D. E., 14 Feb 2018, In: Circulation: Cardiovascular Quality and Outcomes. 11, 2, p. e004227

Research output: Contribution to journal › Article › peer-review

Open Access

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Impact of noncardiac findings in patients undergoing CT coronary angiography: a substudy of the Scottish computed tomography of the heart (SCOT-HEART) trial

Williams, M. C., Hunter, A., Shah, A. S. V., Dreisbach, J., Weir McCall, J. R., Macmillan, M. T., Kirkbride, R., Hawke, F., Baird, A., Mirsadraee, S., van Beek, E. J. R., Newby, D. E. & Roditi, G., 2 Jan 2018, In: European Radiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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2017

A 59-year-old woman with visible precordial pulsations

Moss, A. J., Pessotto, R. & Flapan, A. D., 3 Nov 2017, (E-pub ahead of print) In: Heart.

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Open Access

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End Stage Renal Disease-induced Hypercalcemia May Promote Aortic Valve Calcification via Annexin VI Enrichment of Valve Interstitial Cell Derived-Matrix Vesicles

Cui, L., Rashdan, N. A., Zhu, D., Milne, E., Ajuh, P., Milne, G., Helfrich, M., Lim, K., Prasad, S., Lerman, D., Vesey, A., Dweck, M., Jenkins, W., Newby, D., Farquharson, C. & Macrae, V. E., Nov 2017, In: Journal of Cellular Physiology. 232, 11, p. 2985-2995

Research output: Contribution to journal › Article › peer-review

Open Access

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Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair.

The MA3RS Study Investigators , Newby, D., Forsythe, R., McBride, O., Robson, J., Vesey, A., Chalmers, R., Burns, P., Garden, O. J., Semple, S., Dweck, M., Gray, C., MacGillivray, T., Wang, C., Koutraki, Y. G., Mitchard, N., Cooper, A., van Beek, E., McKillop, G., Ho, W., & 26 othersFraser, L., Cuthbert, H., Hoskins, P., Doyle, B., Conlisk, N., Stuart, W., Berry, C., Roditi, G., Murdoch, L., Holdsworth, R., Scott, E., Milne, L., Strachan, F., Wee, F., Oatey, K., Graham, C., Murray, G., Milne, G., Bucukoglu, M., Goodman, K., Kaczynski, J., Shah, A. S. V., Tambyraja, A., Brittenden, J., Lambie, R. & Norrie, J., 29 Aug 2017, In: Circulation. 136, 9, p. 787–797 11 p.

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Open Access

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Inhaled Nanoparticles Accumulate at Sites of Vascular Disease

Miller, M. R., Raftis, J. B., Langrish, J. P., Mclean, S. G., Samutrtai, P., Connell, S. P., Wilson, S., Vesey, A. T., Fokkens, P. H. B., Boere, A. J. F., Krystek, P., Campbell, C. J., Hadoke, P. W. F., Donaldson, K., Cassee, F. R., Newby, D. E., Duffin, R. & Mills, N. L., 23 May 2017, In: ACS Nano. 11, 5, p. 4542-4552 11 p.

Research output: Contribution to journal › Article › peer-review

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Adverse prognosis associated with asymmetric myocardial thickening in aortic stenosis

Kwiecinski, J., Chin, C. W. L., Everett, R. J., White, A. C., Semple, S., Yeung, E., Jenkins, W. J., Shah, A. S. V., Koo, M., Mirsadraee, S., Lang, C. C., Mills, N., Prasad, S. K., Jansen, M. A., Japp, A. G., Newby, D. E. & Dweck, M. R., 30 Mar 2017, (E-pub ahead of print) In: European Heart Journal - Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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PET Cell Tracking Using 18F-FLT is Not Limited by Local Reuptake of Free Radiotracer

MacAskill, M. G., Tavares, A. S., Wu, J., Lucatelli, C., Mountford, J. C., Baker, A. H., Newby, D. E. & Hadoke, P. W. F., 13 Mar 2017, In: Scientific Reports. 44233 .

Research output: Contribution to journal › Article › peer-review

Open Access

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A 49-year-old with chest pain and collapse

Moss, A. J., Lim, K. H. & Japp, A. G., 11 Mar 2017, In: Heart.

Research output: Contribution to journal › Article › peer-review

Open Access

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Duration of dual antiplatelet therapy in acute coronary syndrome

Wilson, S. J., Newby, D. E., Dawson, D., Irving, J. & Berry, C., 1 Mar 2017, (E-pub ahead of print) In: Heart.

Research output: Contribution to journal › Article › peer-review

Open Access

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Symptoms and Quality of Life in Patients with Suspected Angina Undergoing Coronary Computed Tomography Angiography

Scottish COmputed Tomography of the HEART (SCOT-HEART) Trial Investigators, Williams, M. C., Hunter, A., Shah, A., Assi, V., Lewis, S., Mangion, K., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J., Timmis, A. D., Newby, D. E. & Oatey, K., 28 Feb 2017, In: Heart.

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Open Access

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2016

Myocardial Fibrosis and Cardiac Decompensation in Aortic Stenosis

Chin, C. W. L., Everett, R., Kwiecinski, J., Vesey, A. T., Yeung, E., Esson, G., Jenkins, W., Koo, M., Mirsadraee, S., White, A. C., Japp, A. G., Prasad, S. K., Semple, S., Newby, D. E. & Dweck, M. R., 21 Dec 2016, (E-pub ahead of print) In: JACC: Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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Computed Tomography and Cardiac Magnetic Resonance in Ischemic Heart Disease

Dweck, M. R., Williams, M. C., Moss, A., Newby, D. E. & Fayad, Z. A., 14 Nov 2016, In: Journal of the American College of Cardiology. 68, 20, p. 2201-2216 16 p.

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Open Access

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Complementary role of cardiac CT in the assessment of aortic valve replacement dysfunction

Moss, A., Dweck, M. R., Dreisbach, J. G., Williams, M. C., Mak, S. M., Cartlidge, T., Nicol, E. D. & Morgan-Hughes, G. J., 2 Nov 2016, (E-pub ahead of print) In: Open heart. 3, 2, e000494.

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Open Access

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Smooth muscle enriched long non-coding RNA (SMILR) regulates cell proliferation

Ballantyne, M. D., Pinel, K., Dakin, R., Vesey, A. T., Diver, L., Mackenzie, R., Garcia, R., Welsh, P., Sattar, N., Hamilton, G., Joshi, N., Dweck, M. R., Miano, J. M., McBride, M. W., Newby, D. E., McDonald, R. A. & Baker, A. H., 24 May 2016, In: Circulation. 133, 21, p. 2050-2065 16 p.

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Open Access

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Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus

Venkatasubramanian, S., Noh, R. M., Daga, S., Langrish, J. P., Mills, N. L., Waterhouse, B. R., Hoffmann, E., Jacobson, E. W., Lang, N. N., Frier, B. M. & Newby, D. E., 17 May 2016, In: Open heart. 3, 1, e000402.

Research output: Contribution to journal › Article › peer-review

Open Access

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Monitoring the biological activity of abdominal aortic aneurysms Beyond Ultrasound

Forsythe, R. O., Newby, D. E. & Robson, J. M. J., 15 Feb 2016, (E-pub ahead of print) In: Heart.

Research output: Contribution to journal › Article › peer-review

Open Access

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Identification and prediction of coronary artery plaque rupture using 18F-fluoride positron emission tomography

Research output

Search results