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Identification of convergent gene regulatory pathways as novel targets in Emery-Dreifuss muscular dystrophy
Schirmer, Eric
(Principal Investigator)
School of Biological Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/01/19
→
30/09/21
Funding
UK-based charities:
£145,185.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Genome Organization
Biochemistry, Genetics and Molecular Biology
100%
Metabolic Pathway
Biochemistry, Genetics and Molecular Biology
100%
Knockout Mouse
Biochemistry, Genetics and Molecular Biology
100%
Genomics
Biochemistry, Genetics and Molecular Biology
100%
Gene Expression
Biochemistry, Genetics and Molecular Biology
100%
DNA Template
Biochemistry, Genetics and Molecular Biology
100%
Muscular Dystrophy
Neuroscience
100%
MicroRNA
Biochemistry, Genetics and Molecular Biology
50%
Research output
Research output per year
2022
2022
2022
2
Article
Research output per year
Research output per year
Metabolic, fibrotic, and splicing pathways are all altered in Emery-Dreifuss muscular dystrophy spectrum patients to differing degrees
De Las Heras, J. I.
, Todorow, V., Krečinić-Balić, L., Hintze, S.,
Czapiewski, R.
,
Webb, S.
, Schoser, B., Meinke, P. &
Schirmer, E. C.
,
25 Oct 2022
,
In:
Human Molecular Genetics.
22 p.
, ddac264.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Metabolic Pathway
100%
DNA Template
100%
Muscular Dystrophy
100%
Gene Expression Profiling
50%
Expression Analysis
50%
Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
Czapiewski, R.
, Batrakou, D. G.,
de las Heras, J.
,
Nicholas Carter, R.
, Sivakumar, A., Sliwinska, M.,
Dixon, C.
,
Webb, S.
, Lattanzi, G., Morton, N. M. &
Schirmer, E. C.
,
13 Jan 2022
,
In:
Nature Communications.
13
,
1
,
18 p.
, 321.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Genome Organization
100%
Knockout Mouse
100%
Genomics
100%
MicroRNA
50%
Gene Expression
50%