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Inflammatory mechanisms to suppress Treg cell function in cancer
Anderton, Stephen
(Principal Investigator)
Serrels, Alan
(Co-investigator)
Deanery of Clinical Sciences
Centre for Inflammation Research
Deanery of Molecular, Genetic and Population Health Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/11/16
→
30/04/20
Funding
UK-based charities:
£294,156.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Tumor Immunity
Medicine and Dentistry
100%
Focal Adhesion Kinase Inhibitor
Medicine and Dentistry
100%
Drive
Medicine and Dentistry
100%
Co-Stimulation
Medicine and Dentistry
100%
Focal Adhesion Kinase
Medicine and Dentistry
100%
T Cell
Medicine and Dentistry
100%
Focal Adhesion
Immunology and Microbiology
100%
Immune Evasion
Immunology and Microbiology
100%
Research output
Research output per year
2017
2017
2020
2020
2
Article
Research output per year
Research output per year
T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity
Canel, M.
,
Taggart, D.
,
Sims, A. H.
,
Lonergan, D. W.
,
Waizenegger, I. C.
&
Serrels, A.
,
21 Jan 2020
, (E-pub ahead of print)
In:
eLIFE.
9
, e48092.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
T Cell
100%
Focal Adhesion Kinase
100%
Co-Stimulation
100%
Focal Adhesion Kinase Inhibitor
100%
Tumor Immunity
100%
IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks
Serrels, B.
,
McGivern, N.
,
Canel, M.
,
Byron, A.
,
Johnson, S. C.
,
McSorley, H. J.
,
Quinn, N.
,
Taggart, D.
,
Von Kriegsheim, A.
,
Anderton, S. M.
,
Serrels, A.
&
Frame, M. C.
,
5 Dec 2017
,
In:
Science Signaling.
10
,
508
, eaan8355.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Interleukin 33
100%
Immune Evasion
100%
Focal Adhesion
100%
Focal Adhesion Kinase
100%
Squamous Cell Carcinoma Cell
40%