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Investigating propagation of pathogenic alpha-synuclein in vitro and in vivo
Kunath, Tilo
(Principal Investigator)
School of Biological Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/09/16
→
30/07/21
Funding
UK-based charities:
£297,128.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Synucleins
Medicine & Life Sciences
100%
Synucleinopathies
Medicine & Life Sciences
50%
Human Embryonic Stem Cells
Medicine & Life Sciences
39%
Pluripotent Stem Cells
Medicine & Life Sciences
38%
Dopaminergic Neurons
Medicine & Life Sciences
37%
Clustered Regularly Interspaced Short Palindromic Repeats
Medicine & Life Sciences
37%
Gene Deletion
Medicine & Life Sciences
35%
Cell Line
Medicine & Life Sciences
31%
Research output
Research output per year
2018
2018
2022
2022
2
Article
Research output per year
Research output per year
An isogenic collection of pluripotent stem cell lines with elevated α-synuclein expression validated for neural induction and cortical neuron differentiation
Natalwala, A.
,
Behbehani, R.
,
Yapom, R.
&
Kunath, T.
,
30 May 2022
,
In:
Frontiers in Cell and Developmental Biology.
10
,
16 p.
, 898560.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Synucleins
100%
Pluripotent Stem Cells
77%
Lewy Body Disease
41%
Neurons
40%
Cell Line
39%
Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the
SNCA
gene
Chen, Y.
,
Singh Dolt, K.
,
Kriek, M.
,
Baker, T.
,
Downey, P.
,
Drummond, N. J.
,
Canham, M. A.
,
Natalwala, A.
,
Rosser, S.
&
Kunath, T.
,
25 Nov 2018
, (E-pub ahead of print)
In:
European Journal of Neuroscience.
15 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Synucleins
100%
Synucleinopathies
92%
Clustered Regularly Interspaced Short Palindromic Repeats
75%
Gene Deletion
71%
Dopaminergic Neurons
69%