Investigating the role of TGF¿¿ in the functional imprinting of pulmonary macrophages in health and disease

Research output

Research output per year 2017 2020 2022 2023 2023

• 9 Article
• 1 Chapter (peer-reviewed)

Research output per year

Research output per year

Search results

• 2023

  CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury

  Mckendrick, J. G., Jones, G.-R., Elder, S. S., Watson, E., T’jonck, W., Mercer, E., Magalhaes, M. S., Rocchi, C., Hegarty, L. M., Johnson, A. L., Schneider, C., Becher, B., Pridans, C., Mabbott, N., Liu, Z., Ginhoux, F., Bajenoff, M., Gentek, R., Bain, C. C. & Emmerson, E., 3 Nov 2023, In: Science Immunology. 8, 89

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Salivary Gland 100%
  • Tissue Repair 36%
  • Neck 9%
  • Immunocompetent Cell 9%

• The role of monocyte-derived macrophages in the lung: It’s all about context

  T’jonck, W. & Bain, C. C., 29 Apr 2023, In: International Journal of Biochemistry and Cell Biology. 159, p. 106421

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Infection 100%
  • Macrophage 100%
  • Infectious Agent 50%
  • Inflammation 50%
  • Homeostasis 33%
• 2022

  CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice

  Bain, C. C., Louwe, P. A., Steers, N., Bravo-Blas, A., Hegarty, L., Pridans, C., Milling, S., MacDonald, A. S., Ruckerl, D. & Jenkins, S. J., 4 Aug 2022, In: European Journal of Immunology. 52, 8, p. 1243-1257

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Microflora 100%
  • CD11c 100%
  • Growth Factor 16%
  • Transcription Factors 16%

• Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

  Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Sanchez Garcia, M. A., Lawson, H., Coelho, P., Murphy, F., Griffith, D., Zhang, A., Morrison, T., Ly, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R., Reyes, L., Cooper, G., Clark, S., Lewis, D. & Kelly, V. & 22 others, Spanos, C., Musgrave, K. M., Delaney, L., Harper, I., Scott, J., Parkinson, N., Rostron, A. J., Baillie, J. K., Clohisey, S., Pridans, C., Campana, L., Starkey Lewis, P., Simpson, A. J., Dockrell, D. H., Schwarze, J., Hirani, N., Ratcliffe, P. J., Pugh, C. W., Kranc, K., Forbes, S. J., Whyte, M. K. B. & Walmsley, S. R., 27 May 2022, In: Nature Immunology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Immune Response 100%
  • Immune Landscape 100%
  • Interferon Type I 50%
  • Systemic Inflammation 50%

• Pulmonary macrophages and SARS-Cov2 infection

  Bain, C. C., Rossi, A. G. & Lucas, C. D., 20 Apr 2022, International Review of Cell and Molecular Biology. Mariani, S. A., Cassetta, L. & Galluzzi, L. (eds.). Oxford, UK: Academic Press, Vol. 367. 1 p. (International Review of Cell and Molecular Biology).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  Open Access

  File

  • Infection 100%
  • COVID-19 100%
  • Macrophage 100%
  • Severe Acute Respiratory Syndrome 100%
  • Diseases 100%
• 2021

  The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair

  Mccowan, J., Fercoq, F., Kirkwood, P. M., T’jonck, W., Hegarty, L. M., Mawer, C. M., Cunningham, R., Mirchandani, A. S., Hoy, A., Humphries, D. C., Jones, G.-R., Hansen, C. G., Hirani, N., Jenkins, S. J., Henri, S., Malissen, B., Walmsley, S. R., Dockrell, D. H., Saunders, P. T. K. & Carlin, L. M. & 1 others, Bain, C. C., 19 Nov 2021, In: Science Immunology. 6, 65

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Transcription Factors 100%
  • Alveolar Macrophage 100%
  • Tissue Repair 100%
  • EGR2 100%
  • Infectious Agent 22%
• 2020

  Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

  Bain, C. C., Gibson, D. A., Steers, N. J., Boufea, K., Louwe, P. A., Doherty, C., González-huici, V., Gentek, R., Magalhaes-pinto, M., Shaw, T., Bajénoff, M., Bénézech, C., Walmsley, S. R., Dockrell, D. H., Saunders, P. T. K., Batada, N. N. & Jenkins, S. J., 26 Jun 2020, In: Science Immunology. 5, 48, eabc4466.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Peritoneal Macrophage 100%
  • Macrophage 100%
  • Peritonitis 28%
  • Dimorphism 28%
  • Gene Expression 14%

• Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing

  Ho, G.-T., Cartwright, J. A., Thompson, E. J., Bain, C. C. & Rossi, A. G., 31 Mar 2020, In: Inflammatory Bowel Diseases.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gut 100%
  • Inflammatory Bowel Disease 100%
  • Inflammation 100%
  • Programmed Cell Death 33%
  • Regeneration 33%
• 2018

  Origin, differentiation and function of intestinal macrophages

  Bain, C. & Schridde, A., 27 Nov 2018, (E-pub ahead of print) In: Frontiers in Immunology. 9, 2733.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Gastrointestinal Tract 25%
  • Inflammatory Bowel Disease 25%
  • Homeostasis 25%
  • Intestine 25%
• 2017

  Pro-inflammatory role of monocyte-derived CX3CR1int macrophages in Helicobacter hepaticus-induced colitis

  Bain, C., Oliphant, C. J., Thomson, C. A., Kullberg, M. C. & Mowat, A. M., 4 Dec 2017, (E-pub ahead of print) In: Infection and Immunity.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Helicobacter Hepaticus 100%