Research output per year
Research output per year
Project Details
Key findings
-Demonstrated for the first time that follicular dendritic cells alone are the important sites of TSE agent accumulation in lymphoid tissues.
-Demonstrated for the first time that the specific ablation of PrPC expression only on FDC blocked TSE agent accumulation in lymphoid tissues and subsequent neuroinvasion.
-Demonstrated for the first time that the specific ablation of PrPC expression only on FDC blocked TSE agent accumulation in lymphoid tissues and subsequent neuroinvasion.
| Status | Finished |
|---|---|
| Effective start/end date | 1/05/08 → 31/08/14 |
Funding
- BBSRC: £162,386.00
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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From scientific curiosity to public enemy number one in six short months
Mabbott, N., 14 Apr 2016, In: PLoS Pathogens. 12, 4, e1005371.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Prospects for safe and effective vaccines against prion diseases
Mabbott, N. A., Sept 2015, In: Expert Review of Vaccines. 14, 1, p. 1-4 4 p.Research output: Contribution to journal › Editorial › peer-review
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Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function
McCulloch, L., Brown, K. L. & Mabbott, N. A., Mar 2013, In: Immunology . 138, 3, p. 246-257 12 p.Research output: Contribution to journal › Article › peer-review