Investigation of alpha-synuclein pathogenic mechanisms with human stem cells and neurons

Kunath, Tilo (Principal Investigator)

Status	Finished
Effective start/end date	1/11/12 → 31/10/15

Funding

MRC: £445,306.00

6 Article

An isogenic collection of pluripotent stem cell lines with elevated α-synuclein expression validated for neural induction and cortical neuron differentiation
Natalwala, A., Behbehani, R., Yapom, R. & Kunath, T., 30 May 2022, In: Frontiers in Cell and Developmental Biology. 10, 16 p., 898560.
Research output: Contribution to journal › Article › peer-review

Open Access
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Alpha synuclein aggregation drives ferroptosis: An interplay of iron, calcium and lipid peroxidation
Angelova, P. R., Choi, M. L., Berezhnov, A. V., Horrocks, M., Hughes, C. D., De, S., Rodrigues, M., Yapom, R., Little, D., Dolt, K., Kunath, T., Devine, M. J., Gissen, P., Shchepinov, M. S., Sylantyev, S., Pavlov, E. V., Klenerman, D., Abramov, A. Y. & Gandhi, S., 27 Apr 2020, In: Cell Death & Differentiation (CDD).
Research output: Contribution to journal › Article › peer-review

Open Access
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A synthetic cell permeable antioxidant protects neurons against acute oxidative stress
Drummond, N., Davies, N. O., Lovett, J., Miller, M., Cook, G., Becker, T., Becker, C. G., McPhail, D. & Kunath, T., 19 Sept 2017, (E-pub ahead of print) In: Scientific Reports. 7, 1, 11857.
Research output: Contribution to journal › Article › peer-review

Open Access
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