Is sexual devlopment conserved between birds and mammals

  • Clinton, Mike (Principal Investigator)

Project Details

Key findings

We demonstrated for the first time that vertebrate somatic cells possess an inherent sex-identity. This finding overturned the dogma that the sexual phenotype was largely dependent on hormone action and showed that, in birds at least, sexual differentiation is cell autonomous. This research also resolved a centuries-old question regarding the nature of gynandromorph (half-sider) birds. We demonstrated conclusively that these birds were composed of normal diploid male and female cells.
StatusFinished
Effective start/end date1/05/0830/07/12

Funding

  • BBSRC: £492,825.00

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