Macrophage phenotypes in lung fibrosis and their regulation by hypoxia

2022

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Sanchez Garcia, M. A., Lawson, H., Coelho, P., Murphy, F., Griffith, D., Zhang, A., Morrison, T., Ly, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R., Reyes, L., Cooper, G., Clark, S., Lewis, D., Kelly, V., & 22 othersSpanos, C., Musgrave, K. M., Delaney, L., Harper, I., Scott, J., Parkinson, N., Rostron, A. J., Baillie, J. K., Clohisey, S., Pridans, C., Campana, L., Starkey Lewis, P., Simpson, A. J., Dockrell, D. H., Schwarze, J., Hirani, N., Ratcliffe, P. J., Pugh, C. W., Kranc, K., Forbes, S. J., Whyte, M. K. B. & Walmsley, S. R., 27 May 2022, In: Nature Immunology.

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2019

IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo

Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J., & 2 othersWhyte, M. K. B. & Walmsley, S. R., 15 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235–246 12 p.

Research output: Contribution to journal › Article › peer-review

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2017

Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo

Dickinson, R. S., Murphy, F., Doherty, C., Williams, S., Mirchandani, A., Willson, J. A., Scotti, J. S., Preston, G., Schofield, C. J., Whyte, M. K. B. & Walmsley, S. R., 26 Oct 2017, In: Wellcome Open Research . 2, p. 104

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Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism

Thompson, A. A. R., Dickinson, R. S., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J., Williams, L., Lewis, A., Mirchandani, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N. M., Forbes, S., Stimson, R. H., Hameed, A. G., Arnold, N., Preston, J. A., & 15 othersLawrie, A., Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R. R., Whyte, M. K. B. & Walmsley, S. R., 24 Feb 2017, In: Science Immunology. 2, 8, eaal2861.

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Macrophage phenotypes in lung fibrosis and their regulation by hypoxia

Research output

Search results

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo

Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo

Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism