Mechanisms and consequences of T cell antigen receptor signalling for normal immune homeostasis and the development of autoimmune disease

Zamoyska, Rose (Principal Investigator)

School of Biological Sciences

Status	Finished
Effective start/end date	1/08/17 → 31/07/23

Funding

UK-based charities: £2,348,453.00

2 Article

Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion
Teagle, A. R., Castro-Sanchez, P., Brownlie, R. J., Logan, N., Kapoor, S. S., Wright, D., Salmond, R. J. & Zamoyska, R., 6 Dec 2023, In: Journal for immunotherapy of cancer. 11, 12, 15 p., e007614.
Research output: Contribution to journal › Article › peer-review

Open Access
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Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2
Bray, C., Wright, D., Haupt, S., Thomas, S., Stauss, H. & Zamoyska, R., 12 Nov 2018, In: Frontiers in Immunology. 9, 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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