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Mechanisms of R-loop formation in mammals: interplay with RNA polymerase II regulation and epigenetic modifications.
Skourti Stathaki, Konstantina
(Principal Investigator)
School of Biological Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/10/14
→
30/09/18
Funding
UK-based charities:
£250,000.00
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Locus Control Region
Biochemistry, Genetics and Molecular Biology
100%
R-Loop
Biochemistry, Genetics and Molecular Biology
100%
SALL4
Biochemistry, Genetics and Molecular Biology
100%
Cell Fate
Immunology and Microbiology
100%
DNA Base Composition
Immunology and Microbiology
100%
PRC1
Biochemistry, Genetics and Molecular Biology
75%
Derepression
Biochemistry, Genetics and Molecular Biology
50%
Null Cell
Immunology and Microbiology
33%
Research output
Research output per year
2019
2019
2021
2021
2
Article
Research output per year
Research output per year
SALL4 controls cell fate in response to DNA base composition
Pantier, R.,
Chhatbar, K.
, Quante, T., Skourti Stathaki, K.,
Cholewa-Waclaw, J.
, Alston, G.,
Alexander-Howden, B.
, Yang Lee, H.,
Cook, A. G.
, Spruijt, C. G., Vermeulen, M.,
Selfridge, J.
&
Bird, A. P.
,
18 Feb 2021
,
In:
Molecular Cell.
81
,
4
,
p. 845-858
14 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Cell Fate
100%
DNA Base Composition
100%
SALL4
100%
Null Cell
33%
Downregulation
33%
R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes
Skourti-Stathaki, K., Torlai Triglia, E., Warburton, M., Voigt, P.,
Bird, A.
& Pombo, A.,
7 Mar 2019
,
In:
Molecular Cell.
73
,
5
,
p. 930-945
21 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Locus Control Region
100%
R-Loop
100%
PRC1
75%
Derepression
50%
Polymerase
25%