Research output per year
Research output per year
Project Details
Key findings
Findings below are for the Edinburgh component of this joint grant. The full programme was run from France, by F-Y Bouget, who reports to the ANR in France. The University of Warwick also contributed to another publication.
a.Detailed and conceptual mathematical models of the Ostreococcus clock gene circuit showed the advantages of complexity in clock gene circuits (which Ostreococus lacks) and in their light inputs (which it has).
Troein et al. Current Biology, 2009.
Troein et al. Plant Journal, 2011; Biomodels ID TroeinOstreoClock_Jan2011.
b. Data on the rhythmic transcriptome in Ostreococcus were used to constrain the most detailed mathematical model of starch metabolism yet published, using a novel modelling method: this showed how this very simple cell can help us to understand more plant science than more complex, higher plant systems.
Sorokina et al. BMC Systems Biology, 2011.
c.Establishing Ostreococcus as an experimental system in Edinburgh: this allowed the paradigm-shifting demonstration of transcription-independent circadian rhythms and their coupling or uncoupling from the transcriptional clock gene circuit.
O’Neill et al. Nature, 2011.
Van Ooijen et al. Current Biology, 2011.
a.Detailed and conceptual mathematical models of the Ostreococcus clock gene circuit showed the advantages of complexity in clock gene circuits (which Ostreococus lacks) and in their light inputs (which it has).
Troein et al. Current Biology, 2009.
Troein et al. Plant Journal, 2011; Biomodels ID TroeinOstreoClock_Jan2011.
b. Data on the rhythmic transcriptome in Ostreococcus were used to constrain the most detailed mathematical model of starch metabolism yet published, using a novel modelling method: this showed how this very simple cell can help us to understand more plant science than more complex, higher plant systems.
Sorokina et al. BMC Systems Biology, 2011.
c.Establishing Ostreococcus as an experimental system in Edinburgh: this allowed the paradigm-shifting demonstration of transcription-independent circadian rhythms and their coupling or uncoupling from the transcriptional clock gene circuit.
O’Neill et al. Nature, 2011.
Van Ooijen et al. Current Biology, 2011.
| Status | Finished |
|---|---|
| Effective start/end date | 1/12/07 → 31/05/11 |
Funding
- BBSRC: £418,372.00
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Proteasome Function Is Required for Biological Timing throughout the Twenty-Four Hour Cycle
van Ooijen, G., Dixon, L. E., Troein, C. & Millar, A. J., May 2011, In: Current Biology. 21, 10, p. 869-875 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Circadian rhythms persist without transcription in a eukaryote
O'Neill, J. S., van Ooijen, G., Dixon, L. E., Troein, C., Corellou, F., Bouget, F-Y., Reddy, A. B. & Millar, A. J., 2011, In: Nature. 469, 7331, p. 554-8 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Mathematical model of the clock gene circuit in the alga Ostreococcus tauri
Millar, A., 2011Research output: Other contribution
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ANR-BBSRC Systems Biology initiative Grantholders Workshop
Andrew Millar (Invited speaker)
Dec 2011Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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European Biological Rhythms Society conference
Andrew Millar (Member of programme committee)
Aug 2011Activity: Participating in or organising an event types › Participation in conference
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Society for Experimental Biology Annual Meeting, symposium on Algal Biology
Andrew Millar (Keynote/plenary speaker)
Jul 2011Activity: Participating in or organising an event types › Participation in conference