Research output per year
Research output per year
Project Details
Key findings
The octaheme protein from Shewanella oneidensis is a tetrathionate reductase apparently involved in anaerobic respiration. We probed the roles of active site residues using site-directed mutagenesis along with kinetic analysis, crystallographic structure determination and spectroscopy to show the key role of Cys64 in substrate binding and catalysis, including covalent modification of the cysteine.
| Status | Finished |
|---|---|
| Effective start/end date | 1/10/03 → 30/09/06 |
Funding
- BBSRC: £229,810.00
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Research output
- 2 Article
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An octaheme c-type cytochrome from Shewanella oneidensis can reduce nitrite and hydroxylamine
Atkinson, S., Mowat, C., Reid, G. & Chapman, S., Aug 2007, In: FEBS Letters. 581, 20, p. 3805-3808 4 p.Research output: Contribution to journal › Article › peer-review
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Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation
Mowat, C. G., Rothery, E., Miles, C. S., McIver, L., Doherty, M. K., Drewette, K., Taylor, P., Walkinshaw, M. D., Chapman, S. K. & Reid, G. A., Oct 2004, In: Nature Structural & Molecular Biology. 11, 10, p. 1023-1024 2 p.Research output: Contribution to journal › Article › peer-review