Project Details


We recently used next generation sequencing technology to sequence half a megabase of DNA, covering the TRAX/DISC locus in approximately 1500 individuals. After quality control, all variants with a minor allele frequency (MAF)

Layman's description

Variation in DNA sequences alter an individuals risk of developing mental illness. This project aims to identify more of the variation within and surrounding a set of genes implicated in mental illness. These genes are thought to be functionally related through their interaction with the schizophrenia-risk gene DISC1, study of which is already yielding biological insight into these illnesses.
Effective start/end date1/10/12 → …


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