NMDA receptor-mediated dendritic protein synthesis a potential mechanism for the regulation of synaptic strength

Project Details

Key findings

Data obtained from this project showed that changes in the strength of synaptic inputs (points of communication between neurones) in the hippocampus, a region of the brain associated with learning and memory could occur independently of the soma (cell body) but still in a protein synthesis-dependent manner. This indicated that protein synthesis required for changes in synaptic strength could occur "locally" in the vicinity of the synapse and did not require the soma.
StatusFinished
Effective start/end date1/04/0331/03/06

Funding

  • BBSRC: £227,664.00

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