PhD STUDENT - JOANNE SIMPSON - Supervisor MOHINI GRAY - Research output - University of Edinburgh Research Explorer

2015

A Highly Selective Fluorescent Probe for Direct Detection and Isolation of Mouse Embryonic Stem Cells

Chandran, Y., Kang, N.-Y., Park, S.-J., Alamudi, S. H., Kim, J.-Y., Sahu, S., Su, D., Lee, J., Vendrell, M. & Chang, Y.-T., 1 Nov 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 21

Research output: Contribution to journal › Article › peer-review

Open Access

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Hepatic progenitor cells of biliary origin with liver repopulation capacity

Lu, W.-Y., Bird, T. G., Boulter, L., Tsuchiya, A., Cole, A. M., Hay, T., Guest, R. V., Wojtacha, D., Man, T. Y., Mackinnon, A., Ridgway, R. A., Kendall, T., Williams, M. J., Jamieson, T., Raven, A., Hay, D. C., Iredale, J. P., Clarke, A. R., Sansom, O. J. & Forbes, S. J., Aug 2015, In: Nature Cell Biology. 17, 8, p. 971-983 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Recombinant Ad35 adenoviral proteins as potent modulators of human T cell activation

Hay, J., Carter, D., Lieber, A. & Astier, A. L., Mar 2015, In: Immunology . 144, 3, p. 453-460

Research output: Contribution to journal › Article › peer-review

Open Access

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A magnetic bead-based ligand binding assay to facilitate human kynurenine 3-monooxygenase drug discovery

Wilson, K., Mole, D. J., Homer, N. Z. M., Iredale, J. P., Auer, M. & Webster, S. P., Feb 2015, In: Journal of Biomolecular Screening. 20, 2, p. 292-298 7 p.

Research output: Contribution to journal › Article › peer-review

Toxicology of ZnO and TiO2 nanoparticles on hepatocytes: Impact on metabolism and bioenergetics

Filippi, C., Pryde, A., Cowan, P., Lee, T., Hayes, P., Donaldson, K., Plevris, J. & Stone, V., Feb 2015, In: Nanotoxicology. 9, p. 126-34 9 p.

Research output: Contribution to journal › Article › peer-review

Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

Hellyer, T. P., Morris, A. C., McAuley, D. F., Walsh, T. S., Anderson, N. H., Singh, S., Dark, P., Roy, A. I., Baudouin, S. V., Wright, S. E., Perkins, G. D., Kefala, K., Jeffels, M., McMullan, R., O'Kane, C. M., Spencer, C., Laha, S., Robin, N., Gossain, S. & Gould, K. & 10 others, Ruchaud-Sparagano, M.-H., Scott, J., Browne, E. M., MacFarlane, J. G., Wiscombe, S., Widdrington, J. D., Dimmick, I., Laurenson, I. F., Nauwelaers, F. & Simpson, A. J., Jan 2015, In: Thorax. 70, 1, p. 41-47 7 p.

Research output: Contribution to journal › Article › peer-review

Identification of small molecule inhibitors of RANKL and TNF signalling as anti-inflammatory and antiresorptive agents in mice

Coste, E., Greig, I. R., Mollat, P., Rose, L., Gray, M., Ralston, S. H. & van 't Hof, R. J., Jan 2015, In: Annals of the Rheumatic Diseases. 74, 1, p. 220-226

Research output: Contribution to journal › Article › peer-review

Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity

Zirngibl, M., Fuernrohr, B. G., Janko, C., Munoz, L. E., Voll, R. E., Gregory, C. D., Schett, G. & Herrmann, M., Jan 2015, In: Clinical & Experimental Immunology. 179, 1, p. 39-49 11 p.

Research output: Contribution to journal › Article › peer-review

2014

Emergency department management of early sepsis: a national survey of emergency medicine and intensive care consultants

Jiwaji, Z., Brady, S., McIntyre, L. A., Gray, A. & Walsh, T. S., Dec 2014, In: Emergency Medicine Journal. 31, 12, p. 1000-1005

Research output: Contribution to journal › Article › peer-review

Minimal oxidation and inflammogenicity of pristine graphene with residence in the lung

Schinwald, A., Murphy, F., Askounis, A., Koutsos, V., Sefiane, K., Donaldson, K. & Campbell, C. J., Dec 2014, In: Nanotoxicology. 8, 8, p. 824-832 9 p.

Research output: Contribution to journal › Article › peer-review

The Utility of the Additive EuroSCORE, RIFLE and AKIN Staging Scores in the Prediction and Diagnosis of Acute Kidney Injury after Cardiac Surgery

Duthie, F. A. I., McGeehan, P., Hill, S., Phelps, R., Kluth, D. C., Zamvar, V., Hughes, J. & Ferenbach, D. A., Dec 2014, In: Nephron Clinical Practice. 128, 1-2, p. 29-38 10 p.

Research output: Contribution to journal › Article › peer-review

The PROactive innovative conceptual framework on physical activity

PROactive consortium, Dobbels, F., de Jong, C., Drost, E., Elberse, J., Feridou, C., Jacobs, L., Rabinovich, R., Frei, A., Puhan, M. A., de Boer, W. I., van der Molen, T., Williams, K., Pinnock, H., Troosters, T., Karlsson, N., Kulich, K. & Rüdell, K., 1 Nov 2014, In: European Respiratory Journal. 44, 5, p. 1223-1233 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Poor symptom control is associated with reduced CT segmental airway lumen area in asthmatic smokers

Thomson, N. C., Chaudhuri, R., Spears, M., Messow, C.-M., MacNee, W., Connell, M., Murchison, J. T., Sproule, M. & McSharry, C., 30 Oct 2014, In: Chest Journal. 147, 3, p. 735-744

Research output: Contribution to journal › Article › peer-review

Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver

Macfarlane, D. P., Raubenheimer, P. J., Preston, T., Gray, C. D., Bastin, M. E., Marshall, I., Iredale, J. P., Andrew, R. & Walker, B. R., 1 Oct 2014, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 7, p. G760-768 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Chest CT Measures of Muscle and Adipose Tissue in COPD: Gender-based Differences in Content and in Relationships with Blood Biomarkers

ECLIPSE Investigators, Diaz, A. A., Zhou, L., Young, T. P., McDonald, M.-L., Harmouche, R., Ross, J. C., Estepar, R. S. J., Wouters, E. F. M., Coxson, H. O., MacNee, W., Rennard, S., Maltais, F., Kinney, G. L., Hokanson, J. E. & Washko, G. R., Oct 2014, In: Academic Radiology. 21, 10, p. 1255-1261 7 p.

Research output: Contribution to journal › Article › peer-review

Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma

Chaudhuri, R., McSharry, C., Brady, J., Grierson, C., Messow, C. M., Spears, M., Miele, G., Nocka, K., MacNee, W., Connell, M., Murchison, J. T., Sproule, M., Hilmi, O. J., Miller, D. K. & Thomson, N. C., Oct 2014, In: European Respiratory Journal. 44, 4, p. 895-904 10 p.

Research output: Contribution to journal › Article › peer-review

Mouse Kidney Transplantation: Models of Allograft Rejection

Tse, G. H., Hesketh, E. E., Clay, M., Borthwick, G., Hughes, J. & Marson, L. P., Oct 2014, In: Journal of Visualized Experiments. 92, e52163.

Research output: Contribution to journal › Article › peer-review

Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces

Lucendo-Villarin, B., Cameron, K., Szkolnicka, D., Travers, P., Khan, F., Walton, J. G., Iredale, J., Bradley, M. & Hay, D. C., 26 Sept 2014, In: Journal of Visualized Experiments (JoVE). 91, e51723.

Research output: Contribution to journal › Article › peer-review

Evaluating the role of inflammation in chronic airways disease: the ERICA study

ERICA Consortium, Mohan, D., Gale, N. S., McEniery, C. M., Bolton, C. E., Cockcroft, J. R., MacNee, W., Fuld, J., Lomas, D. A., Calverley, P. M. A., Shale, D. J., Miller, B. E., Wilkinson, I. B., Tal-Singer, R. & Polkey, M. I., Sept 2014, In: COPD: Journal of Chronic Obstructive Pulmonary Disease. 11, 5, p. 552-9 8 p.

Research output: Contribution to journal › Article › peer-review

Constitutive apoptosis in equine peripheral blood neutrophils in vitro

Brazil, T. J., Dixon, P. M., Haslett, C., Murray, J. & McGorum, B. C., 29 Aug 2014, In: Veterinary Journal. 202, 3, p. 536-542

Research output: Contribution to journal › Article › peer-review

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Controlled Exposures to Air Pollutants and Risk of Cardiac Arrhythmia

Langrish, J. P., Watts, S. J., Hunter, A. J., Shah, A., Bosson, J. A., Unosson, J., Barath, S., Lundback, M., Cassee, F. R., Donaldson, K., Sandstrom, T., Blomberg, A., Newby, D. E. & Mills, N. L., Jul 2014, In: Environmental Health Perspectives. 122, 7, p. 747-753 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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A specialist, second-tier response to out-of-hospital cardiac arrest: setting up TOPCAT2

Clarke, S., Lyon, R. M., Short, S., Crookston, C. & Clegg, G. R., May 2014, In: Emergency Medicine Journal. 31, 5, p. 405-7 3 p.

Research output: Contribution to journal › Article › peer-review

Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo

Fallowfield, J. A., Hayden, A. L., Snowdon, V. K., Aucott, R. L., Stutchfield, B. M., Mole, D. J., Pellicoro, A., Gordon-Walker, T. T., Henke, A., Schrader, J., Trivedi, P. J., Princivalle, M., Forbes, S. J., Collins, J. E. & Iredale, J. P., Apr 2014, In: Hepatology. 59, 4, p. 1492–1504 13 p.

Research output: Contribution to journal › Article › peer-review

Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation

Brittan, M., Barr, L. C., Anderson, N., Conway-Morris, A., Duffin, R., Marwick, J. A., Rossi, F., Johnson, S., Dhaliwal, K., Hirani, N., Rossi, A. G. & Simpson, A. J., 31 Mar 2014, In: Journal of inflammation. 11, 1, 9.

Research output: Contribution to journal › Article › peer-review

Open Access

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Bacterial expression of human kynurenine 3-monooxygenase: Solubility, activity, purification

Wilson, K., Mole, D. J., Binnie, M., Homer, N. Z. M., Zheng, X., Yard, B. A., Iredale, J. P., Auer, M. & Webster, S. P., Mar 2014, In: Protein Expression and Purification. 95, p. 96-103 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist

Sarvi, S., Mackinnon, A. C., Avlonitis, N., Bradley, M., Rintoul, R. C., Rassl, D. M., Wang, W., Forbes, S. J., Gregory, C. D. & Sethi, T., Mar 2014, In: Cancer Research. 74, 5, p. 1554-1565 12 p.

Research output: Contribution to journal › Article › peer-review

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

Pellicoro, A., Ramachandran, P., Iredale, J. P. & Fallowfield, J. A., Mar 2014, In: Nature Reviews Immunology. 14, 3, p. 181-194 14 p.

Research output: Contribution to journal › Article › peer-review

Nutritional rehabilitation after ICU - does it happen: a qualitative interview and observational study

Merriweather, J., Smith, P. & Walsh, T., Mar 2014, In: Journal of Clinical Nursing. 23, 5-6, p. 654-62 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Surface functionalization affects the zeta potential, coronal stability and membranolytic activity of polymeric nanoparticles

Cho, W.-S., Thielbeer, F., Duffin, R., Johansson, E. M. V., Megson, I. L., MacNee, W., Bradley, M. & Donaldson, K., Mar 2014, In: Nanotoxicology. 8, 2, p. 202-211 10 p.

Research output: Contribution to journal › Article › peer-review

Effector and central memory T helper 2 cells respond differently to peptide immunotherapy

Mackenzie, K. J., Nowakowska, D. J., Leech, M. D., McFarlane, A. J., Wilson, C., Fitch, P. M., O'Connor, R. A., Howie, S. E. M., Schwarze, J. & Anderton, S. M., 25 Feb 2014, In: Proceedings of the National Academy of Sciences (PNAS). 111, 8, p. E784-E793 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Helminths and immunological tolerance

Johnston, C. J. C., McSorley, H. J., Anderton, S. M., Wigmore, S. J. & Maizels, R. M., 27 Jan 2014, In: Transplantation. 97, 2, p. 127-32 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages

Kallis, Y. N., Scotton, C. J., Mackinnon, A. C., Goldin, R. D., Wright, N. A., Iredale, J. P., Chambers, R. C. & Forbes, S. J., 27 Jan 2014, In: PLoS ONE. 9, 1, p. e86241

Research output: Contribution to journal › Article › peer-review

Open Access

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Dispatch-assisted CPR: Where are the hold-ups during calls to emergency dispatchers? A preliminary analysis of caller-dispatcher interactions during out-of-hospital cardiac arrest using a novel call transcription technique

Clegg, G. R., Lyon, R. M., James, S., Branigan, H. P., Bard, E. G. & Egan, G. J., Jan 2014, In: Resuscitation. 85, 1, p. 49-52

Research output: Contribution to journal › Article › peer-review

Paradoxical effects of heme arginate on survival of myocutaneous flaps

Edmunds, M.-C., Czopek, A., Wigmore, S. J. & Kluth, D. C., Jan 2014, In: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 306, 1, p. R10-R22 13 p.

Research output: Contribution to journal › Article › peer-review

Viral respiratory tract infections and asthma in early life: cause and effect?

Mackenzie, K. J., Anderton, S. M. & Schwarze, J., Jan 2014, In: Clinical & Experimental Allergy. 44, 1, p. 9-19 11 p.

Research output: Contribution to journal › Literature review › peer-review

2013

Open Access

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Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients

Morris, A. C., Anderson, N., Brittan, M., Wilkinson, T. S., McAuley, D. F., Antonelli, J., McCulloch, C., Barr, L. C., Dhaliwal, K., Jones, R. O., Haslett, C., Hay, A. W., Swann, D. G., Laurenson, I. F., Davidson, D. J., Rossi, A. G., Walsh, T. S. & Simpson, A. J., Nov 2013, In: British Journal of Anaesthesia. 111, 5, p. 778-787 10 p.

Research output: Contribution to journal › Article › peer-review

Distance learning improves attainment of professional milestones in the early years of surgical training

Smith, P. J. W., Wigmore, S. J., Paisley, A., Lamb, P., Richards, J. M. J., Robson, A. J., Revie, E., McKeown, D., Dewhurst, D. & Garden, O. J., Nov 2013, In: Annals of Surgery. 258, 5, p. 838-43 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Validity of physical activity monitors during daily life in patients with COPD

on behalf of the PROactive consortium., Rabinovich, R. A., Louvaris, Z., Raste, Y., Langer, D., Remoortel, H. V., Giavedoni, S., Burtin, C., Regueiro, E. M. G., Vogiatzis, I., Hopkinson, N. S., Polkey, M. I., Wilson, F. J., Macnee, W., Westerterp, K. R. & Troosters, T., Nov 2013, In: European Respiratory Journal. 42, 5, p. 1205-1215 11 p.

Research output: Contribution to journal › Article › peer-review

Effectiveness of telemonitoring integrated into existing clinical services on hospital admission for exacerbation of chronic obstructive pulmonary disease: researcher blind, multicentre, randomised controlled trial

Pinnock, H., Hanley, J., McCloughan, L., Todd, A., Krishan, A., Lewis, S., Stoddart, A., van der Pol, M., Macnee, W., Sheikh, A., Pagliari, C. & McKinstry, B., 17 Oct 2013, In: British Medical Journal (BMJ). 347, p. f6070

Research output: Contribution to journal › Article › peer-review

Open Access

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Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease

TESRA and ECLIPSE Investigators, Cheng, D. T., Kim, D. K., Cockayne, D. A., Belousov, A., Bitter, H., Cho, M. H., Duvoix, A., Edwards, L. D., Lomas, D. A., Miller, B. E., Reynaert, N., Tal-Singer, R., Wouters, E. F. M., Agustí, A., Fabbri, L. M., Rames, A., Visvanathan, S., Rennard, S. I. & Jones, P. & 6 others, Parmar, H., MacNee, W., Wolff, G., Silverman, E. K., Mayer, R. J. & Pillai, S. G., 15 Oct 2013, In: American Journal of Respiratory and Critical Care Medicine. 188, 8, p. 948-57 10 p.

Research output: Contribution to journal › Article › peer-review

A Comparative Study of 2 Computer-assisted Methods of Quantifying Brightfield Microscopy Images

Tse, G. H. & Marson, L. P., Oct 2013, In: Applied Immunohistochemistry & Molecular Morphology (AIMM). 21, 5, p. 464-470 7 p.

Research output: Contribution to journal › Article › peer-review

Cationic Host Defence Peptides: Potential as Antiviral Therapeutics

Gwyer Findlay, E., Currie, S. M. & Davidson, D. J., Oct 2013, In: BioDrugs. 27, 5, p. 479-493 15 p.

Research output: Contribution to journal › Literature review › peer-review

Open Access

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Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma

Thomson, N. C., Chaudhuri, R., Messow, C. M., Spears, M., Macnee, W., Connell, M., Murchison, J. T., Sproule, M. & McSharry, C., Oct 2013, In: Respiratory Medicine. 107, 10, p. 1501-8 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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PhD STUDENT - JOANNE SIMPSON - Supervisor MOHINI GRAY

Research output

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