Poly (A)-binding proteins highlighted the importance of regulated mRNA translation and stability in determing a functional materno-fetal interface

Gray, Niki (Principal Investigator)
Girardi, Guillermina (Co-investigator)
Norman, Jane (Co-investigator)

6 Article

6 results

2017
Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding
Smith, R. W. P., Anderson, R. C., Larralde, O., Smith, J. W. S., Gorgoni, B., Richardson, W. A., Malik, P., Graham, S. V. & Gray, N. K., 13 Jun 2017, In: Proceedings of the National Academy of Sciences (PNAS). 114, 24, p. 6310-6315
Research output: Contribution to journal › Article › peer-review

Open Access
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2016
Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation
Brook, M., Tomlinson, G. H., Miles, K., Smith, R. W. P., Rossi, A. G., Hiemstra, P. S., van 't Wout, E. F. A., Dean, J. L. E., Gray, N. K., Lu, W. & Gray, M., 19 Apr 2016, In: Proceedings of the National Academy of Sciences (PNAS). 113, 16, p. 4350-4355 6 p.
Research output: Contribution to journal › Article › peer-review

File
2014
Poly(A)-binding proteins are required for diverse biological processes in metazoans
Smith, R. W. P., Blee, T. K. P. & Gray, N. K., 1 Aug 2014, In: Biochemical Society Transactions. 42, 4, p. 1229-37 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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2012
The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover
Brook, M. & Gray, N. K., Aug 2012, In: Biochemical Society Transactions. 40, 4, p. 856-64 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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An integrated model for the nucleo-cytoplasmic transport of cytoplasmic poly(A)-binding proteins
Burgess, H. M. & Gray, N. K., May 2012, In: Communicative and Integrative Biology. 5, 3, p. 243-247 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities
Brook, M., McCracken, L., Reddington, J. P., Lu, Z-L., Morrice, N. A. & Gray, N. K., Feb 2012, In: Biochemical Journal. 441, 3, p. 803-812 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Poly (A)-binding proteins highlighted the importance of regulated mRNA translation and stability in determing a functional materno-fetal interface

Research output

Search results

Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding

Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation

Poly(A)-binding proteins are required for diverse biological processes in metazoans

The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover

An integrated model for the nucleo-cytoplasmic transport of cytoplasmic poly(A)-binding proteins

The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities