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PROGRAMME GRANT
Hupp, Ted
(Principal Investigator)
Deanery of Molecular, Genetic and Population Health Sciences
Edinburgh Cancer Research Centre
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/09/06
→
29/02/12
Funding
UK-based charities:
£1,110,800.00
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
P53
Biochemistry, Genetics and Molecular Biology
100%
Protein
Biochemistry, Genetics and Molecular Biology
89%
Conformation
Biochemistry, Genetics and Molecular Biology
85%
Alpha Oxidation
Biochemistry, Genetics and Molecular Biology
85%
Dimerization
Biochemistry, Genetics and Molecular Biology
85%
Ubiquitination
Biochemistry, Genetics and Molecular Biology
85%
Mutant
Biochemistry, Genetics and Molecular Biology
85%
Cysteine
Biochemistry, Genetics and Molecular Biology
85%
Research output
Research output per year
2010
2010
2016
2016
2
Article
Research output per year
Research output per year
Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond
Clarke, D. J.
,
Murray, E.
,
Faktor, J.
,
Mohtar, A.
,
Vojtesek, B.
,
MacKay, C. L.
,
Smith, P. L.
&
Hupp, T. R.
,
May 2016
,
In:
BBA - Bioenergetics.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Alpha Oxidation
100%
Protein
100%
Cysteine
100%
Disulfide Bond
100%
Dimerization
100%
A Novel p53 Phosphorylation Site within the MDM2 Ubiquitination Signal: II. A model in which phosphorylation at Ser269 induces a mutant conformation to p53.
Fraser, J. A.
,
Madhumalar, A.
,
Blackburn, E.
,
Bramham, J.
,
Walkinshaw, M. D.
,
Verma, C.
&
Hupp, T. R.
,
Nov 2010
,
In:
Journal of Biological Chemistry.
285
,
48
,
p. 37773-37786
14 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Ubiquitination
100%
Conformation
100%
Mutant
100%
Phosphorylation
100%
P53
100%