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The development of SERS-based protein-protein interaction assays to evaluate bioactivity of Antibody-conjugates in cell signalling
Hupp, Ted
(Principal Investigator)
Deanery of Molecular, Genetic and Population Health Sciences
Edinburgh Cancer Research Centre
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/09/13
→
31/08/17
Funding
BBSRC:
£93,520.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Nutlin
Biochemistry, Genetics and Molecular Biology
100%
Protein-Protein Interaction
Biochemistry, Genetics and Molecular Biology
52%
Protein Protein Interaction
Immunology and Microbiology
52%
Pyruvate Dehydrogenase
Biochemistry, Genetics and Molecular Biology
50%
Dihydrolipoamide Dehydrogenase
Biochemistry, Genetics and Molecular Biology
50%
PD-L1
Biochemistry, Genetics and Molecular Biology
50%
CD276
Biochemistry, Genetics and Molecular Biology
50%
Receptor Blocking
Biochemistry, Genetics and Molecular Biology
50%
Research output
Research output per year
2016
2016
2020
2020
2
Article
Research output per year
Research output per year
The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276
Li, R.
,
Zatloukalova, P.
,
Muller, P.
,
Gil mir, M.
,
Kote, S.
,
Wilkinson, S.
,
Kemp, A. J.
,
Hernychova, L.
,
Wang, Y.
,
Ball, K. L.
,
Tao, K.
,
Hupp, T. R.
&
Vojtesek, B.
,
31 Aug 2020
, (E-pub ahead of print)
In:
Cellular & Molecular Biology Letters.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
PD-L1
100%
Nutlin
100%
Receptor Blocking
100%
CD276
100%
Nutlin 3
100%
Rearrangement of Mitochondrial Pyruvate Dehydrogenase Subunit Dihydrolipoamide Dehydrogenase Protein-Protein Interactions by the MDM2 Ligand Nutlin-3.
Way, L.
,
Faktor, J.
,
Dvorakova, P.
,
Nicholson, J.
,
Vojtesek, B.
,
Graham, D.
,
Ball, K. L.
&
Hupp, T.
,
5 Sept 2016
,
In:
Proteomics.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Protein-Protein Interaction
100%
Dihydrolipoamide Dehydrogenase
100%
Nutlin
100%
Pyruvate Dehydrogenase
100%
Ligand
100%