Research output per year
Research output per year
Research output
- 27 Article
- 27 results
Search results
-
2023
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
Gluszek-Kustusz, A., Craske, B., Legal, T., Mchugh, T. & Welburn, J. P. I., 2 Nov 2023, In: The EMBO journal. 42, 21, 18 p., e113647.Research output: Contribution to journal › Article › peer-review
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Direct recruitment of Mis18 to interphase spindle pole bodies promotes CENP-A chromatin assembly
London, N., Medina-Pritchard, B., Spanos, C., Rappsilber, J., Jeyaprakash, A. A. & Allshire, R. C., 9 Oct 2023, In: Current Biology. 33, 19, p. 4187-4201 22 p.Research output: Contribution to journal › Article › peer-review
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Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation
Lee, S. C., Adams, D. W., Ipsaro, J. J., Cahn, J., Lynn, J., Kim, H-S., Berube, B., Major, V., Calarco, J. P., LeBlanc, C., Bhattacharjee, S., Ramu, U., Grimanelli, D., Jacob, Y., Voigt, P., Joshua-Tor, L. & Martienssen, R. A., 14 Sept 2023, In: Cell. 186, 19Research output: Contribution to journal › Article › peer-review
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2022
H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function
Li, J., Bergmann, L., Rafael de Almeida, A., Webb, K. M., Gogol, MM., Voigt, P., Liu, Y., Liang, H. & Smolle, MM., 21 Mar 2022, In: Nucleic Acids Research. 50, 5, p. 2549-2565 17 p., gkac077.Research output: Contribution to journal › Article › peer-review
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The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication
Davarinejad, H., Huang, Y-C., Mermaz, B., Leblanc, C., Poulet, A., Thomson, G., Joly, V., Muñoz, M., Arvanitis-Vigneault, A., Valsakumar, D., Villarino, G., Ross, A., Rotstein, B. H., Alarcon, E. I., Brunzelle, J. S., Voigt, P., Dong, J., Couture, J-F. & Jacob, Y., 17 Mar 2022, In: Science. 375, 6586, p. 1281-1286 6 p.Research output: Contribution to journal › Article › peer-review
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2020
The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment
Legal, T., Hayward, D., Gluszek-Kustusz, A., Blackburn, E., Spanos, C., Rappsilber, J., Gruneberg, U. & Welburn, J. P. I., 25 Aug 2020, In: Journal of Cell Science. 133, 16, 11 p., jcs246025.Research output: Contribution to journal › Article › peer-review
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Spt6 is a maintenance factor for centromeric CENP-A
Bobkov, G., Huang, A., van den Berg, S. J. W., Mitra, S., Anselm, E., Lazou, V., Schunter, S., Feederle, R., Imhof, A., Lusser, A., Jansen, L. E. T. & Heun, P., 10 Jun 2020, In: Nature Communications. 11, 1, 2919.Research output: Contribution to journal › Article › peer-review
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Wash‐free, peptide‐based fluorogenic probes for microbial imaging
Baibek, A., Üçüncü, M., Blackburn, E. A., Bradley, M. & Lilienkampf, A., 7 May 2020, (E-pub ahead of print) In: Peptide Science. e24167.Research output: Contribution to journal › Article › peer-review
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Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1
Medina-Pritchard, B., Lazou, V., Zou, J., Byron, O., Abad Fernandez, M., Rappsilber, J., Heun, P. & Arulanandam, J., 5 Mar 2020, In: EMBO Journal. e103234.Research output: Contribution to journal › Article › peer-review
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ChromID identifies the protein interactome at chromatin marks
Villaseñor, R., Pfaendler, R., Ambrosi, C., Butz, S., Giuliani, S., Bryan, E., Sheahan, T. W., Gable, A. L., Schmolka, N., Manzo, M., Wirz, J., Feller, C., von Mering, C., Aebersold, R., Voigt, P. & Baubec, T., 2 Mar 2020, In: Nature Biotechnology. 38, 6, p. 728-736 9 p.Research output: Contribution to journal › Article › peer-review
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PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1
Belotserkovskaya, R., Raga Gil, E., Lawrence, N., Butler, R., Clifford, G., Wilson, M. D. & Jackson, S. P., 10 Feb 2020, In: Nature Communications. 11, p. 1-11 11 p., 819.Research output: Contribution to journal › Article › peer-review
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2019
Borealin–nucleosome interaction secures chromosome association of the chromosomal passenger complex
Abad, M. A., Ruppert, J., Buzuk, L., Wear, M., Zou, J., Webb, K., Kelly, D., Voigt, P., Rappsilber, J., Earnshaw, W. & Arulanandam, A., 30 Sept 2019, In: Journal of Cell Biology. 218, 12, p. 3912–3925 13 p.Research output: Contribution to journal › Article › peer-review
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Reconstitution of microtubule nucleation in vitro reveals novel roles for Mzt1
Leong, S. L., Lynch, E. M., Zou, J., Tay, Y. D., Borek, W. E., Tuijtel, M. W., Rappsilber, J. & Sawin, K. E., 8 Jul 2019, In: Current Biology. 29, 13, p. 2199-2207 9 p., E10.Research output: Contribution to journal › Article › peer-review
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2018
ALDH1 bio-activates nifuroxazide to eradicate ALDHHigh melanoma-initiating cells
Sarvi, S., Crispin, R., Lu, Y., Zeng, L., Hurley, T. D., Houston, D. R., von Kriegsheim, A., Chen, C-H., Mochly-Rosen, D., Ranzani, M., Mathers, M. E., Xu, X., Xu, W., Adams, D. J., Carragher, N. O., Fujita, M., Schuchter, L., Unciti-Broceta, A., Brunton, V. G. & Patton, E. E., 20 Dec 2018, In: Cell Chemical Biology. 25, 12, p. 1456-1469.e6 20 p.Research output: Contribution to journal › Article › peer-review
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Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation
Mitchell, A. R., Yuan, M., Morgan, H. P., McNae, I. W., Blackburn, E. A., LeBihan, T., Homem, R. A., Yu, M., Loake, G. J., Michels, P. A., Wear, M. A. & Walkinshaw, M. D., 31 Oct 2018, In: Biochemical Journal. 475, 20, p. 3275-3291 17 p.Research output: Contribution to journal › Article › peer-review
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An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor
Yuan, M., McNae, I. W., Chen, Y., Blackburn, E. A., Wear, M. A., Michels, P. A. M., Fothergill-Gilmore, L. A., Hupp, T. & Walkinshaw, M. D., 31 May 2018, In: Biochemical Journal. 475, 10, p. 1821-1837 17 p.Research output: Contribution to journal › Article › peer-review
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Molecular Dynamics Simulations of Site Point Mutations in the TPR domain of Cyclophilin 40 Identify Conformational States with Distinct Dynamic and Enzymatic Properties
Gur, M., Blackburn, E., Ning, J., Narayan, V., Ball, K., Walkinshaw, M. & Erman, B., 9 Apr 2018, (E-pub ahead of print) In: The Journal of Chemical Physics. 148, 145101.Research output: Contribution to journal › Article › peer-review
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2017
HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33
Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., Le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzàlez-cìscar, A., Errington, C., Vermeren, S., Astier, A. L., Wallace, W. A., & 4 others, 17 Oct 2017, In: Immunity. 47, 4, p. 739-751.e5 18 p.Research output: Contribution to journal › Article › peer-review
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Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition
Yuan, M., Vásquez-Valdivieso, M. G., McNae, I. W., Michels, P. A. M., Fothergill-Gilmore, L. A. & Walkinshaw, M. D., 13 Oct 2017, In: Journal of Molecular Biology. 429, 20, p. 3075-3089Research output: Contribution to journal › Article › peer-review
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Molecular Basis for Cdk1 Regulated Timing of Mis18 Complex Assembly and CENP-A Deposition
Spiller, F., Medina-Pritchard, B., Alba Abad, M., Wear, M., Molina, O., Earnshaw, W. & Arulanandam, A., 4 Apr 2017, In: EMBO Reports. e201643564.Research output: Contribution to journal › Article › peer-review
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Thermo-kinetic analysis space expansion for cyclophilin-ligand interactions; identification of a new non-peptide inhibitor using Biacore™ T200
Wear, M., Nowicki, M., Blackburn, E., McNae, I. & Walkinshaw, M., 23 Feb 2017, In: FEBS Open Bio.Research output: Contribution to journal › Article › peer-review
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Inhibition of antigen-specific and non-specific stimulation of bovine T and B cells by lymphostatin from attaching and effacing Escherichia coli
Cassady-Cain, R., Blackburn, E., Bell, C., Elshina, E., Hope, J. & Stevens, M., Feb 2017, In: Infection and Immunity. 85, 2, e00845-16 .Research output: Contribution to journal › Article › peer-review
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2016
Design of Nucleotide-Mimetic and Non-Nucleotide Inhibitors of the Translation Initiation Factor eIF4E: Synthesis, Structural and Functional Characterisation
Nowicki, M. W., Soukarieh, F., Bastide, A., Poyry, T., Jones, C., Dudek, K., Patwardhan, G., Meullenet, F., Oldham, N. J., Walkinshaw, M. D., Willis, A. E. & Fischer, P. M., 24 Aug 2016, (E-pub ahead of print) In: European Journal of Medicinal Chemistry. 124, p. 200-217 17 p.Research output: Contribution to journal › Article › peer-review
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Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli
Cassady-Cain, R. L., Blackburn, E. A., Alsarraf, H., Dedic, E., Bease, A. G., Böttcher, B., Jørgensen, R., Wear, M. & Stevens, M. P., 11 Mar 2016, In: Journal of Biological Chemistry. 291, 11, p. 5803-5816Research output: Contribution to journal › Article › peer-review
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2015
A streamlined, automated protocol for the production of milligram quantities of untagged recombinant rat lactate dehydrogenase A using ÄKTAxpress™
Nowicki, M., Blackburn, E., McNae, I. & Wear, M., 30 Dec 2015, In: PLoS ONE. 10, 12, e0146164.Research output: Contribution to journal › Article › peer-review
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Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90
Blackburn, E. A., Wear, M. A., Landré, V., Narayan, V., Ning, J., Erman, B., Ball, K. L. & Walkinshaw, M. D., 1 Oct 2015, In: Bioscience reports. 35, 5, e00258.Research output: Contribution to journal › Article › peer-review
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UFSRAT: Ultra-fast shape recognition with atom types -The discovery of novel bioactive small molecular scaffolds for FKBP12 and 11βHSD1
Shave, S., Blackburn, E. A., Adie, J., Houston, D. R., Auer, M., Webster, S. P., Taylor, P. & Walkinshaw, M. D., 6 Feb 2015, In: PLoS ONE. 10, 2, p. e0116570Research output: Contribution to journal › Article › peer-review
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