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The functional role of macrophages in the progression and resolution of lung fibrosis
Forbes, Stuart
(Principal Investigator)
Iredale, John
(Co-investigator)
Sethi, Tariq
(Co-investigator)
Deanery of Clinical Sciences
Centre for Inflammation Research
Centre for Regenerative Medicine
University of Edinburgh
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
15/05/07
→
31/07/10
Funding
MRC:
£238,654.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Pulmonary Fibrosis
Medicine and Dentistry
100%
Regulatory Mechanism
Medicine and Dentistry
100%
Idiopathic Pulmonary Fibrosis
Medicine and Dentistry
52%
Monocyte
Medicine and Dentistry
50%
Macrophage
Medicine and Dentistry
50%
Transforming Growth Factor
Medicine and Dentistry
50%
Galectin 3
Medicine and Dentistry
50%
Lung
Immunology and Microbiology
50%
Research output
Research output per year
2011
2011
2012
2012
2
Article
Research output per year
Research output per year
Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3
Mackinnon, A. C.
,
Gibbons, M. A.
,
Farnworth, S. L.
,
Leffler, H.
,
Nilsson, U. J.
,
Delaine, T.
,
Simpson, A. J.
,
Forbes, S. J.
,
Hirani, N.
,
Gauldie, J.
&
Sethi, T.
,
1 Mar 2012
,
In:
American Journal of Respiratory and Critical Care Medicine.
185
,
5
,
p. 537-546
10 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Transforming Growth Factor
100%
Regulatory Mechanism
100%
Galectin 3
100%
Pulmonary Fibrosis
100%
Lung
100%
Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis
Gibbons, M. A.
,
MacKinnon, A. C.
,
Ramachandran, P.
,
Dhaliwal, K.
,
Duffin, R.
,
Phythian-Adams, A. T.
,
van Rooijen, N.
,
Haslett, C.
,
Howie, S. E.
,
Simpson, A. J.
,
Hirani, N.
,
Gauldie, J.
,
Iredale, J. P.
,
Sethi, T.
&
Forbes, S. J.
,
2011
,
In:
American Journal of Respiratory and Critical Care Medicine.
184
,
5
,
p. 569-81
13 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Regulatory Mechanism
100%
Pulmonary Fibrosis
100%
Macrophage
100%
Monocyte
100%
Therapeutic Procedure
50%